MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Interaction Map	Gene	green	Rank	Filtered	description	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 486 to 535 of 3228 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided

green	Rank	description	network_comparison	red
46	150	myosin vb (myosin 5b) (fragment). [swissprot;acc:q9ulv0]	1.19565	55
	151	myosin vc (myosin 5c). [swissprot;acc:q9nqx4]
	152	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]
49	140	ras-related gtp binding a; ras-related gtp-binding protein. [refseq;acc:nm_006570]	1.20408	59
	141	ras-related gtp binding c; rag c protein. [refseq;acc:nm_022157]
	142	ras-related gtp binding b short isoform; gtp-binding protein ragb. [refseq;acc:nm_006064]
	143	anillin, actin binding protein (scraps homolog, drosophila); anillin (drosophila scraps homolog), actin binding protein. [refseq;acc:nm_018685]
75.3531	14	cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936]	1.32952	56.6768
75.3948	15	microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8]	1.32914	56.7244
75.3954	16	microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492]	1.32913	56.7252
75.447	17	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	1.32866	56.7841
78.8995	322	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	1.09948	86.7483
83.0461	48	gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278]	1.26868	65.4586
97.4011	592	protein phosphatase 1, regulatory subunit 7; sds22. [refseq;acc:nm_002712]	1.06298	91.63
98.0548	168	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	1.18722	82.5916
	169	apg3p; pc3-96 protein. [refseq;acc:nm_022488]
101.613	397	t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368]	1.08932	110.689
105	49	beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]	1.26667	133
	50	beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]
	51	spermatogenesis associated 6. [refseq;acc:nm_019073]
	52	amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433]
110.265	83	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	1.24949	88.2482
	84	hepatocellular carcinoma-associated protein hca3. [refseq;acc:nm_138703]
	85	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]
	86	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
	87	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
	88	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
	89	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
	90	necdin. [swissprot;acc:q99608]
	91	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
	92	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]
	93	melanoma antigen, family b, 6. [refseq;acc:nm_173523]
	94	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
	95	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]
	96	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
	97	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]
	98	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]
	99	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
	100	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]
	101	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]
	102	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]
	103	trophinin. [swissprot;acc:q12816]
112.329	850	cleavage and polyadenylation specific factor 4, 30kd subunit; cleavage-polyadenylation specificity factor, 30kd; no arches-like (zebrafish) zinc finger protein; cleavage-polyadenylation specificity factor. [refseq;acc:nm_006693]	1.04161	107.842
	851	trs85 homolog. [swissprot;acc:q9y2l5]
112.772	853	wd-repeat protein wdc146. [swissprot;acc:q9c0j8]	1.0414	108.289
	854	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]
114	126	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	1.21277	94
	127	putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453]
	128	associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]
	129	neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.