MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	Network Comparison Type	Value Type	Interaction Map	green	description	network_comparison	red	Filtered

Results: HTML CSV LaTeX

Showing element 1127 to 1176 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	green	description	network_comparison	red
1127	232.837	nucleolar protein nop5 (nucleolar protein 5) (nop58) (hspc120). [swissprot;acc:q9y2x3]	1.02741	239.219
1128	215.399	homeobox protein six1 (sine oculis homeobox homolog 1). [swissprot;acc:q15475]	1.02733	221.286
1129	215.401	homeobox protein six2 (sine oculis homeobox homolog 2). [swissprot;acc:q9npc8]	1.02732	221.285
1130	215.4	proliferation-associated protein 2g4 (cell cycle protein p38-2g4 homolog) (hg4-1). [swissprot;acc:q9uq80]
1131	212.675	vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670]	1.02731	218.484
1132		apoptosis inhibitor 5; fibroblast growth factor 2-interacting factor 2; api5-like 1. [refseq;acc:nm_006595]
1133		sec13-related protein. [swissprot;acc:p55735]
1134		vacuolar atp synthase subunit g 3 (ec 3.6.3.14) (v-atpase g subunit 3) (vacuolar proton pump g subunit 3) (v-atpase 13 kda subunit 3). [swissprot;acc:q96lb4]
1135		vacuolar atp synthase subunit b, brain isoform (ec 3.6.3.14) (v-atpase b2 subunit) (vacuolar proton pump b isoform 2) (endomembrane proton pump 58 kda subunit) (ho57). [swissprot;acc:p21281]
1136		yeast sec31p homolog. [refseq;acc:nm_014933]
1137		vacuolar atp synthase subunit g 1 (ec 3.6.3.14) (v-atpase g subunit 1) (vacuolar proton pump g subunit 1) (v-atpase 13 kda subunit 1) (vacuolar atp synthase subunit m16). [swissprot;acc:o75348]
1138		vacuolar atp synthase subunit e (ec 3.6.3.14) (v-atpase e subunit) (vacuolar proton pump e subunit) (v-atpase 31 kda subunit) (p31). [swissprot;acc:p36543]
1139		ganglioside-induced differentiation-associated protein 1-like 1. [refseq;acc:nm_024034]
1140		dead (asp-glu-ala-asp) box polypeptide 39 isoform 1; nuclear rna helicase, decd variant of dead box family. [refseq;acc:nm_005804]
1141		ganglioside-induced differentiation-associated protein 1. [refseq;acc:nm_018972]
1142		vacuolar atp synthase subunit d (ec 3.6.3.14) (v-atpase d subunit) (vacuolar proton pump d subunit) (v-atpase 28 kda accessory protein). [swissprot;acc:q9y5k8]
1143		secretory pathway component sec31b-1. [refseq;acc:nm_015490]
1144		vacuolar atp synthase subunit h (ec 3.6.3.14) (v-atpase h subunit) (vacuolar proton pump h subunit) (v-atpase 50/57 kda subunits) (vacuolar proton pump subunit sfd) (cgi-11). [swissprot;acc:q9ui12]
1145		vacuolar atp synthase subunit f (ec 3.6.3.14) (v-atpase f subunit) (vacuolar proton pump f subunit) (v-atpase 14 kda subunit). [swissprot;acc:q16864]	1.0273	218.481
1146	212.676	vacuolar atp synthase subunit b, kidney isoform (ec 3.6.3.14) (v- atpase b1 subunit) (vacuolar proton pump b isoform 1) (endomembrane proton pump 58 kda subunit). [swissprot;acc:p15313]		218.483
1147	203.109	peroxisomal membrane protein pex14 (peroxin-14) (peroxisomal membrane anchor protein pex14) (pts1 receptor docking protein). [swissprot;acc:o75381]	1.02729	208.651
1148	203.518	ubiquitin. [swissprot;acc:p02248]	1.02724	209.061
1149	233.185	bystin. [swissprot;acc:q13895]	1.0271	239.505
1150	215.522	sorting nexin 1. [swissprot;acc:q13596]	1.02694	209.868
1151	204.925	metaxin 1. [swissprot;acc:q13505]	1.02693	199.552
1152	216.143	epidermal growth factor receptor pathway substrate 8-like protein 1 isoform c; epidermal growth factor receptor pathway substrate 8-related protein 1; eps8-related protein 1. [refseq;acc:nm_139204]	1.02682	221.939
1153	216.146	epidermal growth factor receptor kinase substrate eps8. [swissprot;acc:q12929]	1.02676	221.93
1154	230.242	inorganic pyrophosphatase (ec 3.6.1.1) (pyrophosphate phospho- hydrolase) (ppase). [swissprot;acc:q15181]	1.02646	224.307
1155		inorganic pyrophosphatase 2 isoform 1. [refseq;acc:nm_176869]
1156		aryl-hydrocarbon interacting protein-like 1. [swissprot;acc:q9nzn9]
1157		ah receptor-interacting protein (aip) (immunophilin homolog ara9) (hbv-x associated protein 2). [swissprot;acc:o00170]
1158	216.167	epidermal growth factor receptor pathway substrate 8-like protein 2; eps8-related protein 2; epidermal growth factor receptor pathway substrate 8-related protein 2. [refseq;acc:nm_022772]	1.02641	221.877
1159	165.898	proline synthetase co-transcribed bacterial homolog protein. [swissprot;acc:o94903]		170.28
1160	214.041	2-oxoglutarate dehydrogenase e1 component, mitochondrial precursor (ec 1.2.4.2) (alpha-ketoglutarate dehydrogenase). [swissprot;acc:q02218]	1.02633	208.55
1161	215.097	kappa b-ras 1. [refseq;acc:nm_020345]	1.02632	220.758
1162		i-kappa-b-interacting ras-like protein 2. [refseq;acc:nm_017595]
1163		snare associated protein snapin. [refseq;acc:nm_012437]
1164	213.818	transducin-like enhancer protein 4. [swissprot;acc:q04727]	1.02628	219.438
1165	213.785	transducin-like enhancer protein 3 (esg3). [swissprot;acc:q04726]	1.02627	219.401
1166	213.759	transducin-like enhancer protein 2 (esg2). [swissprot;acc:q04725]		219.374
1167	213.784	homeobox protein engrailed-2 (hu-en-2). [swissprot;acc:p19622]	1.02626	219.399
1168		cpg binding protein (protein containing phd finger and cxxc domain 1). [swissprot;acc:q9p0u4]
1169		activator of basal transcription 1; tata-binding protein-binding protein; basal transcriptional activator. [refseq;acc:nm_013375]
1170		cytokine-like nuclear factor n-pac. [refseq;acc:nm_032569]
1171		hect type e3 ubiquitin ligase. [refseq;acc:nm_015052]
1172	213.767	transducin-like enhancer protein 1 (esg1). [swissprot;acc:q04724]	1.02623	219.375
1173	235.246	candidate tumor suppressor in ovarian cancer 2. [refseq;acc:nm_080822]	1.02619	229.243
1174	192.849	coatomer epsilon subunit (epsilon-coat protein) (epsilon-cop). [swissprot;acc:o14579]	1.02599	187.964
1175	212.672	vacuolar atp synthase 16 kda proteolipid subunit (ec 3.6.3.14). [swissprot;acc:p27449]	1.02593	218.186
1176		sarcoglycan zeta; zeta-sarcoglycan. [refseq;acc:nm_139167]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.