MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	network_comparison	green	Interaction Map	description	Network Comparison Type	Value Type	red	Rank	Gene

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0
network_comparison  : 0
green  : 0
Network Comparison Type  : Subtracted
red  : 0

Interaction Map	description	Value Type	Rank
High confidence	brca1 associated protein. [refseq;acc:nm_006768]	Measured	502
		Ranked
		Squared
		Rooted
	h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Measured	501
		Squared
		Rooted
	histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured	495
		Squared
		Rooted
	histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured	494
		Squared
		Rooted
	histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured	497
		Squared
		Rooted
	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Measured	499
		Ranked	501
		Squared	499
		Rooted
	mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured	496
		Squared
		Rooted
	rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	Measured	500
		Squared
		Rooted
	translin-associated protein x (translin-associated factor x). [swissprot;acc:q99598]	Measured	498
		Squared
		Rooted
Low confidence	cobw-like protein. [refseq;acc:nm_018491]	Measured	839
		Ranked
		Squared
		Rooted
	gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Measured	838
		Ranked
		Squared
		Rooted
	gamma-glutamyltransferase. [sptrembl;acc:q14390]	Measured	841
		Ranked
		Squared
		Rooted
	gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	Measured	842
		Ranked
		Squared
		Rooted
	gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]	Measured	837
		Ranked
		Squared
		Rooted
	gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	Measured	843

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.