MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 4608 to 4657 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

Rank	description	Value Type	Network Comparison Type	red	green	network_comparison
576	limkain b1. [refseq;acc:nm_019081]	Squared	Subtracted	31994	36719.6	4725.6
577	60s ribosomal protein l15. [swissprot;acc:p39030]	Ranked		217.862	230.978	13.116
	acid ceramidase precursor (ec 3.5.1.23) (acylsphingosine deacylase) (n-acylsphingosine amidohydrolase) (ac) (putative 32 kda heart protein) (php32). [swissprot;acc:q13510]	Squared	Divided	36109.8	42811.6	1.1856
	band 4.1-like protein 3 (4.1b) (differentially expressed in adenocarcinoma of the lung protein 1) (dal-1). [swissprot;acc:q9y2j2]	Measured	Subtracted	7813.45	8570.07	756.62
	enteropeptidase precursor (ec 3.4.21.9) (enterokinase). [swissprot;acc:p98073]	Ranked	Divided	224.606	210.944	1.06477
	gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928]	Measured		6739.81	7644.62	1.13425
	homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444]	Rooted		121.695	131.815	1.08316
	nadph-cytochrome p450 reductase (ec 1.6.2.4) (cpr) (p450r). [swissprot;acc:p16435]		Subtracted	50.3803	45.4193	4.961
	putative adenosylhomocysteinase 3 (ec 3.3.1.1) (s-adenosyl-l- homocysteine hydrolase) (adohcyase). [swissprot;acc:q96hn2]	Squared		31994	36719.6	4725.6
578	cellular repressor of e1a-stimulated genes. [refseq;acc:nm_003851]
	cholinephosphate cytidylyltransferase b (ec 2.7.7.15) (phosphorylcholine transferase b) (ctp:phosphocholine cytidylyltransferase b) (ct b) (cct b) (cct-beta). [swissprot;acc:q9y5k3]	Rooted		50.3803	45.4193	4.961
	forkhead box protein g1c (forkhead-related protein fkhl3) (hfk3) (fragment). [swissprot;acc:q14488]	Measured	Divided	6739.81	7644.62	1.13425
	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	Rooted		121.695	131.815	1.08316
	importin alpha-6 subunit (karyopherin alpha-5 subunit). [swissprot;acc:o15131]	Squared		23534.9	27890.2	1.18506
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Ranked	Subtracted	15	28	13
	protein 4.1 (band 4.1) (p4.1) (epb4.1) (4.1r). [swissprot;acc:p11171]	Measured		7813.35	8569.96	756.61
	splicing factor 3b subunit 2 (spliceosome associated protein 145) (sap 145) (sf3b150) (pre-mrna splicing factor sf3b 145 kda subunit). [swissprot;acc:q13435]	Ranked	Divided	224.606	210.944	1.06477
579	band 4.1-like protein 1 (neuronal protein 4.1) (4.1n). [swissprot;acc:q9h4g0]	Measured	Subtracted	7813.34	8569.95	756.61
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked		15	28	13
	disks large-associated protein 3 (dap-3) (sap90/psd-95-associated protein 3) (sapap3) (psd-95/sap90 binding protein 3) (fragment). [swissprot;acc:o95886]	Squared		31994	36719.6	4725.6
	gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3]	Measured	Divided	6739.82	7644.62	1.13425
	homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016]	Rooted		121.695	131.815	1.08316
	preimplantation protein 3; likely ortholog of preimplantation protein 3. [refseq;acc:nm_015387]		Subtracted	63.1463	68.1044	4.9581
	voltage-gated potassium channel beta-3 subunit (k+ channel beta-3 subunit) (kv-beta-3). [swissprot;acc:o43448]	Squared	Divided	23526.4	27879.4	1.18503
	zinc finger protein t86. [swissprot;acc:o00488]	Ranked		246.805	231.796	1.06475
580	band 4.1-like protein 2 (generally expressed protein 4.1) (4.1g). [swissprot;acc:o43491]	Measured	Subtracted	7813.36	8569.97	756.61
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Ranked		15	28	13
	dnaj homolog subfamily b member 11 precursor (er-associated dnaj protein 3) (erj3) (er-associated hsp40 co-chaperone) (hdj9) (pwp1- interacting protein 4). [swissprot;acc:q9ubs4]	Rooted		63.1463	68.1044	4.9581
	gamma-aminobutyric-acid receptor alpha-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p47869]	Measured	Divided	6739.83	7644.63	1.13425
	homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067]	Rooted		121.695	131.815	1.08316
	kininogen precursor (alpha-2-thiol proteinase inhibitor) [contains: bradykinin]. [swissprot;acc:p01042]	Squared	Subtracted	31994	36719.6	4725.6
	yip1 interacting factor homolog; yip1p-interacting factor; putative rab5-interacting protein; putative transmembrane protein 54tmp. [refseq;acc:nm_020470]		Divided	23526.4	27879.3	1.18502
	zinc ribbon domain containing, 1; transcription-associated zinc ribbon protein; rna polymerase i small specific subunit rpa12. [refseq;acc:nm_014596]	Ranked		236.751	252.038	1.06457
581	cytohesin 4. [swissprot;acc:q9uia0]		Subtracted	15	28	13
	disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	Squared		31994	36719.6	4725.6
	galectin-9 (hom-hd-21) (ecalectin). [swissprot;acc:o00182]	Measured		7810.11	8566.29	756.18
	gamma-aminobutyric-acid receptor alpha-6 subunit precursor (gaba(a) receptor). [swissprot;acc:q16445]		Divided	6739.82	7644.63	1.13425
	homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719]	Rooted		121.695	131.815	1.08316
	imp2 inner mitochondrial membrane protease-like; inner mitochondrial membrane peptidase 2 like. [refseq;acc:nm_032549]		Subtracted	59.7294	64.6872	4.9578
	t-cell leukemia homeobox protein 3 (homeobox protein hox-11l2). [swissprot;acc:o43711]	Ranked	Divided	237.28	252.492	1.06411
	voltage-gated potassium channel beta-1 subunit (k+ channel beta-1 subunit) (kv-beta-1). [swissprot;acc:q14722]	Squared		23526.4	27879.3	1.18502
582	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Ranked	Subtracted	15	28	13
	ferritin light chain (ferritin l subunit). [swissprot;acc:p02792]	Squared		31994	36719.6	4725.6
	gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507]	Measured	Divided	6739.82	7644.62	1.13425
	homeobox protein barh-like 1. [swissprot;acc:q9hbu1]	Ranked		237.28	252.492	1.06411
	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	Rooted		121.695	131.815	1.08316
	microsomal signal peptidase 18 kda subunit (ec 3.4.-.-) (spase 18 kda subunit) (spc18) (endopeptidase sp18). [swissprot;acc:p21378]		Subtracted	59.7294	64.6872	4.9578
	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	Measured		6834.54	7590.49	755.95
	similar to putative transmembrane protein; homolog of yeast golgi membrane protein yif1p (yip1p-interacting factor). [refseq;acc:nm_033557]	Squared	Divided	23526.4	27879.3	1.18502
583	aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [swissprot;acc:o95154]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.