Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Gene description green Rank red Value Type network_comparison Interaction Map Network Comparison Type
Results: HTML CSV LaTeX Showing element 1 to 50 of 77072 in total
Filtered  : 0
description
green
Rank
red
Value Type
network_comparison
Interaction Map
Network Comparison Type
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 17.0804 537 16.298 Rooted 1.04801 Low confidence Divided
634 0.7824 Subtracted
18.0183 53 11.844 1.5213 High confidence Divided
69 6.1743 Subtracted
851.77 131 645.504 Measured 1.31954 Low confidence Divided
273 206.266 Subtracted
934.348 37 334.401 2.79409 High confidence Divided
45 599.947 Subtracted
1034.13 37 101.05 Squared 10.2338 Divided
131 933.08 Subtracted
1268.51 146 775.72 1.63527 Low confidence Divided
319 492.79 Subtracted
13590.3 600 13205.3 Ranked 385
629 1.02915 Divided
13895.8 172 15260.6 1364.8 High confidence Subtracted
242 1.09822 Divided
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829] 39.5126 726 39.0982 Rooted 0.4144 Low confidence Subtracted
768 1.0106 Divided
4869.42 627 4825.89 Measured 43.53 Subtracted
778 1.00902 Divided
10050.9 627 10347.7 Ranked 1.02953
641 296.8 Subtracted
40451 536 40270.8 Squared 180.2
815 1.00447 Divided
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] 0.344399 26 44.3683 128.828 High confidence
336 44.0239 Subtracted
3.80565 26 13.7805 Rooted 3.62106 Divided
28 9.97485 Subtracted
9.42485 131 11.365 1.20585 Low confidence Divided
376 1.94015 Subtracted
26.1599 19 305.45 Measured 11.6763 High confidence Divided
115 279.29 Subtracted
181.734 171 222.779 1.22585 Low confidence Divided
635 41.045 Subtracted
296.481 697 307.765 Squared 1.03806 Divided
749 11.284 Subtracted
14695.2 220 13533.1 Ranked 1162.1
384 1.08587 Divided
18499.2 28 12941.7 5557.5 High confidence Subtracted
47 1.42943 Divided
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832] 23.2445 793 23.11 Rooted 1.00582 Low confidence
797 0.1345 Subtracted
32.0298 335 30.7424 1.2874 High confidence
370 1.04188 Divided
1609.88 762 1593.68 Measured 16.2 Low confidence Subtracted
771 1.01017 Divided
2642.79 380 2683.61 40.82 High confidence Subtracted
451 1.01545 Divided
6490.54 584 6603.33 Squared 112.79 Low confidence Subtracted
763 1.01738 Divided

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/