Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description green Filtered red Interaction Map Value Type network_comparison Network Comparison Type Gene Rank
Results: HTML CSV LaTeX Showing element 451 to 500 of 2121 in total
green  : 0
Filtered  : 1
red  : 0
network_comparison  : 0
Network Comparison Type  : Subtracted
description
Interaction Map
Value Type
Rank
double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279] Low confidence Rooted 5048
doublesex and mab-3 related transcription factor 3; testis-specific protein; dmrt-like family a3. [refseq;acc:nm_021240] High confidence Measured 3187
Ranked
Squared
Rooted
dual specificity protein phosphatase 11 (ec 3.1.3.48) (rna/rnp complex-intereracting phosphatase) (phosphatase that interacts with rna/rnp complex 1). [swissprot;acc:o75319] Measured 2926
Ranked
Squared
Rooted
dynein 2 light intermediate chain. [refseq;acc:nm_016008] Measured 2962
Ranked
Squared
Rooted
dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46] Measured 3029
Ranked
Squared
Rooted
ecotropic virus integration 1 site protein. [swissprot;acc:q03112] Measured 3170
Ranked
Squared
Rooted
ell-associated factor 2; uncharacterized bone marrow protein bm040; testosterone regulated apoptosis inducer and tumor suppressor. [refseq;acc:nm_018456] Measured 2921
Ranked
Squared
Rooted
elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897] Measured 3027
Ranked
Squared
Rooted
endosome-associated fyve-domain protein. [refseq;acc:nm_014733] Measured 3200
Ranked
Squared
Rooted
enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800] Measured 3090
Ranked
Squared
Rooted
enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910] Measured 3098
Ranked
Squared
Rooted
ergic-53 protein precursor (er-golgi intermediate compartment 53 kda protein) (lectin, mannose-binding 1) (gp58) (intracellular mannose specific lectin mr60). [swissprot;acc:p49257] Measured 3177
Ranked
Squared
Rooted
erythroid differentiation-related factor 1. [refseq;acc:nm_015608] Measured 3095
Ranked
Squared
Rooted
eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765] Measured 2868

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/