MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	Value Type	Network Comparison Type	green	description	red	Interaction Map	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

Rank	Value Type	green	description	red	Interaction Map	Filtered	network_comparison
1	Measured	0.00001	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	364	High confidence	0	36400000
					Low confidence
		543.5	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	2399.5		1	4.4149
		2394.5	rad50-interacting protein 1. [refseq;acc:nm_021930]	450.5	High confidence		5.31521
	Ranked	24	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	10			2.4
		32	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	16	Low confidence		2
		14977	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	5865		0	2.55362
		15915	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	4294	High confidence		3.70633
	Squared	1.87479	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	0.00001	Low confidence		187479
		7.16592	cab2. [refseq;acc:nm_033419]		High confidence		716592
		69.9153	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	1362.75	Low confidence	1	19.4914
		1357.07	rad50-interacting protein 1. [refseq;acc:nm_021930]	48.0356	High confidence		28.2513
	Rooted	0.00001	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	19.0788		0	1907880
					Low confidence
		23.3131	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	48.9847		1	2.10117
		48.9336	rad50-interacting protein 1. [refseq;acc:nm_021930]	21.225	High confidence		2.30547
2	Measured	89	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	0.00001	Low confidence	0	8900000
		174	cab2. [refseq;acc:nm_033419]		High confidence		17400000
		543.5	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	2399.5	Low confidence	1	4.4149
		2394.5	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	450.5	High confidence		5.31521
	Ranked	28	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	15			1.86667
		330	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	223	Low confidence		1.47982
		14977	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	5865	High confidence	0	2.55362
		21883	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]	8906	Low confidence		2.45711
	Squared	0.00001	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	5.61325	High confidence		561325
		1.87479	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	0.00001	Low confidence		187479
		69.9153	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	1362.75		1	19.4914
		1357.07	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	48.0356	High confidence		28.2513
	Rooted	0.00001	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]	12.4097		0	1240970
		9.43398	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	0.00001	Low confidence		943398
		23.3131	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	48.9847		1	2.10117
		48.9336	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	21.225	High confidence		2.30547
3	Measured	89	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	0.00001	Low confidence	0	8900000
		109	pyridoxine 5'-phosphate oxidase. [refseq;acc:nm_018129]		High confidence		10900000
		543.5	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	2399.5	Low confidence	1	4.4149
		698.5	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	2597.5	High confidence		3.71868
	Ranked	28	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	15			1.86667
		330	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	223	Low confidence		1.47982
		11083.9	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]	4475.84	High confidence	0	2.47638
		20617	neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531]	9607	Low confidence		2.14604
	Squared	0.00001	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	5.61325	High confidence		561325
		1.87479	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	0.00001	Low confidence		187479
		69.9153	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	1362.75		1	19.4914
		115.48	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	1596.92	High confidence		13.8285
	Rooted	0.00001	transducin beta-like 1y protein (transducin-beta-like 1, y-linked). [swissprot;acc:q9bq87]	12.4097		0	1240970
		9.43398	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	0.00001	Low confidence		943398
		23.3131	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	48.9847		1	2.10117
		26.4292	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	50.9657	High confidence		1.92839
4	Measured	89	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]	0.00001	Low confidence	0	8900000
			homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]		High confidence

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.