MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Network Comparison Type	Gene	Value Type	Hugo	Interaction Map	red	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 3180 to 3229 of 66312 in total

Filtered  : 1

description	Rank	Network Comparison Type	Value Type	Hugo	Interaction Map	red	green	network_comparison
actin binding lim protein 2. [refseq;acc:nm_032432]	1937	Subtracted	Squared	ABLIM2	High confidence	28264.4	30386.4	2122
	2127		Measured		Low confidence	7670	7921.78	251.78
	2332	Divided	Squared		High confidence	28264.4	30386.4	1.07508
	3513				Low confidence	43742.1	42371.9	1.03234
	3597	Subtracted						1370.2
actin, alpha cardiac. [swissprot;acc:p04270]	914			ACTC1		45895	43771.9	2123.1
	966	Divided						1.0485
	3923	Subtracted	Rooted			72.384	74.3873	2.0033
	3960	Divided						1.02768
	3962		Ranked			200.879	198.479	1.01209
	3973	Subtracted						2.4
	4021	Divided	Measured			8073.06	8251.68	1.02213
	4148	Subtracted						178.62
actin, aortic smooth muscle (alpha-actin 2). [swissprot;acc:p03996]	917		Squared	ACTA2		45894.9	43772	2122.9
	967	Divided						1.0485
	3924	Subtracted	Rooted			72.3846	74.3879	2.0033
	3961	Divided						1.02768
	3964		Ranked			200.877	198.477	1.01209
	3974	Subtracted						2.4
	4022	Divided	Measured			8073.12	8251.74	1.02213
	4149	Subtracted						178.62
actin, cytoplasmic 2 (gamma-actin). [swissprot;acc:p02571]	1206		Squared	ACTG1	High confidence	28554.8	31619.6	3064.8
	1280		Measured			6036.22	6512.64	476.42
	1284		Rooted			63.0056	65.7244	2.7188
	1307	Divided						1.04315
	1354		Measured			6036.22	6512.64	1.07893
	1529		Ranked			216.762	213.031	1.01751
	1536	Subtracted						3.731
	1636	Divided	Squared			28554.8	31619.6	1.10733
	1671				Low confidence	45216.3	43374.8	1.04246
	1737	Subtracted						1841.5
	3385		Measured			8001.89	8213.1	211.21
	3418	Divided						1.0264
	3425	Subtracted	Rooted			72.1822	74.3776	2.1954
	3454	Divided						1.03041
	3630		Ranked			200.633	197.828	1.01418
	3638	Subtracted						2.805
actin, gamma-enteric smooth muscle (alpha-actin 3). [swissprot;acc:p12718]	916		Squared	ACTG2		45894.9	43772	2122.9
	965	Divided						1.0485
	3922	Subtracted	Rooted			72.3846	74.3879	2.0033
	3959	Divided						1.02768
	3961		Ranked			200.877	198.477	1.01209
	3972	Subtracted						2.4
	4020	Divided	Measured			8073.12	8251.74	1.02213
	4147	Subtracted						178.62
actin-binding lim protein 1 isoform a; lim actin-binding protein 1; limatin; actin-binding lim protein. [refseq;acc:nm_002313]	629		Rooted	ABLIM1	High confidence	60.0129	64.7371	4.7242
	633		Ranked			229.072	216.576	12.496
	640	Divided	Rooted			60.0129	64.7371	1.07872
	668		Ranked			229.072	216.576	1.0577
	776	Subtracted			Low confidence	208.488	203.181	5.307

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.