MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Interaction Map	Filtered	Gene	Rank	green	description	red	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 282 to 331 of 3228 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided

Rank	green	description	red	network_comparison
282	228.297	chromatin assembly factor 1 subunit c (caf-1 subunit c) (chromatin assembly factor i p48 subunit) (caf-i 48 kda subunit) (caf-ip48) (retinoblastoma binding protein p48) (retinoblastoma-binding protein 4) (rbbp-4) (msi1 protein homolog). [swissprot;acc:q09028]	252.39	1.10553
283	267.346	60s ribosomal protein l11. [swissprot;acc:p39026]	241.828	1.10552
284	203.235	crk-associated substrate (p130cas) (breast cancer anti-estrogen resistance 1 protein). [swissprot;acc:p56945]	224.657	1.10541
285	203.242	t-complex protein 1, delta subunit (tcp-1-delta) (cct-delta) (stimulator of tar rna binding). [swissprot;acc:p50991]	224.647	1.10532
286	203.251	enhancer of filamentation 1 (hef1) (crk-associated substrate-related protein) (cas-l) (casl) (pp105) (neural precursor cell expressed developmentally down-regulated 9). [swissprot;acc:q14511]	224.633	1.1052
287	266.079	40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47]	240.758	1.10517
288	266.078	40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750]
289	246.892	hpaii tiny fragments locus 9c. [refseq;acc:nm_022727]	272.781	1.10486
290	210.064	ribonucleoside-diphosphate reductase m2 chain (ec 1.17.4.1) (ribonucleotide reductase small chain). [swissprot;acc:p31350]	231.969	1.10428
291	228.037	nuclear transcription factor y subunit beta (nf-y protein chain b) (nf-yb) (ccaat-binding transcription factor subunit a) (cbf-a) (caat- box dna binding protein subunit b). [swissprot;acc:p25208]	251.679	1.10368
292	266.414	40s ribosomal protein s15a. [swissprot;acc:p39027]	241.411	1.10357
293	265.717	60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	240.782	1.10356
294		brca2 and cdkn1a-interacting protein isoform bccipalpha; brca2 and cdkn1a-interacting protein; cdk inhibitor p21 binding protein; bccipalpha; bccipbeta; tok-1alpha; tok-1beta. [refseq;acc:nm_016567]
295	202.423	multisynthetase complex auxiliary component p43 [contains: endothelial-monocyte activating polypeptide ii (emap-ii) (small inducible cytokine subfamily e member 1)]. [swissprot;acc:q12904]	223.273	1.103
296	266.12	mitochondrial ribosomal protein l4 isoform a. [refseq;acc:nm_015956]	241.282	1.10294
297	259.984	60s ribosomal protein l7. [swissprot;acc:p18124]	235.727	1.1029
298	243.588	calpain 2, large [catalytic] subunit precursor (ec 3.4.22.17) (calcium-activated neutral proteinase) (canp) (m-type) (m-calpain) (millimolar-calpain) (calpain large polypeptide l2). [swissprot;acc:p17655]	268.632	1.10281
299	243.592	calpain 1, large [catalytic] subunit (ec 3.4.22.17) (calcium-activated neutral proteinase) (canp) (mu-type) (mucanp) (micromolar-calpain). [swissprot;acc:p07384]	268.635
300	166.351	metalloprotease 1; metalloprotease 1 (pitrilysin family). [refseq;acc:nm_014889]	150.959	1.10196
301	166.372	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	150.982	1.10193
302	267.008	60s ribosomal protein l26. [swissprot;acc:q02877]	242.326	1.10185
303	266.999	60s ribosomal protein l35. [swissprot;acc:p42766]	242.333	1.10179
304	266.986	40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	242.339	1.1017
305		mitochondrial ribosomal protein l2. [refseq;acc:nm_015950]
306	266.673	60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	242.153	1.10126
307		serine racemase (ec 5.1.1.-). [swissprot;acc:q9gzt4]
308		60s ribosomal protein l34. [swissprot;acc:p49207]
309		protein transport protein sec61 alpha subunit isoform 2 (sec61 alpha- 2). [swissprot;acc:q9y2r3]
310		protein transport protein sec61 alpha subunit isoform 1 (sec61 alpha- 1). [swissprot;acc:p38378]
311	267.151	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	242.627	1.10108
312	266.663	60s ribosomal protein l3-like. [swissprot;acc:q92901]	242.195	1.10103
313	211.207	ribonucleotide reductase m2 b (tp53 inducible); p53-inducible ribonucleotide reductase small subunit 2 homolog. [refseq;acc:nm_015713]	232.473	1.10069
314	268.604	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	244.126	1.10027
315		methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]
316	267.017	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	242.694	1.10022
317	204.044	splicing factor 3b subunit 3 (spliceosome associated protein 130) (sap 130) (sf3b130) (pre-mrna splicing factor sf3b 130 kda subunit). [swissprot;acc:q15393]	224.445	1.09998
318	266.18	mitochondrial 60s ribosomal protein l3 (l3mt). [swissprot;acc:p09001]	242.011	1.09987
319	264.729	60s ribosomal protein l19. [swissprot;acc:p14118]	240.73	1.09969
320	265.96	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [swissprot;acc:p12830]	241.892	1.0995
321	265.959	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [sptrembl;acc:q9br02]		1.09949
322	78.8995	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	86.7483	1.09948
323	265.945	60s ribosomal protein l23a. [swissprot;acc:p29316]	241.884	1.09947
324	268.195	40s ribosomal protein s23. [swissprot;acc:p39028]	243.944	1.09941
325		28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]
326	265.924	60s ribosomal protein l5. [swissprot;acc:p46777]	241.899	1.09932
327	267.962	dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [swissprot;acc:p24928]	243.817	1.09903
328	235.183	atp-dependent rna helicase ddx24 (dead-box protein 24). [swissprot;acc:q9gzr7]	258.437	1.09888
329	284	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	312	1.09859
330		chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]
331		doc-1 related protein (doc-1r). [swissprot;acc:o75956]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.