MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	green	Value Type	network_comparison	Gene	Rank	Interaction Map	description	red	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 951 to 1000 of 77072 in total

Filtered  : 0

green	Value Type	network_comparison	Rank	Interaction Map	description	red	Network Comparison Type
12.1701	Rooted	0.3373	455	High confidence	signal-induced proliferation-associated 1-like 1. [refseq;acc:nm_015556]	12.5074	Subtracted
		1.02772	432				Divided
12.1722		1.3321	86		mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	9.13761
			89	Low confidence
		3.03459	170	High confidence			Subtracted
			272	Low confidence
12.2043		1.15882	165		transcription factor bteb4 (basic transcription element binding- protein 4) (bte-binding protein 4) (krueppel-like factor 16) (novel sp1-like zinc finger transcription factor 2) (transcription factor nslp2). [swissprot;acc:q9bxk1]	10.5317	Divided
		1.6726	432				Subtracted
12.2755		0.4846	711		amiloride-sensitive sodium channel gamma-subunit (epithelial na+ channel gamma subunit) (gamma enac) (nonvoltage-gated sodium channel 1 gamma subunit) (scneg) (gamma nach). [swissprot;acc:p51170]	11.7909
		1.0411	570				Divided
12.2759		0.4852	710		amiloride-sensitive cation channel 3 isoform a; testis sodium channel 1; proton-gated cation channel subunit; modulatory subunit of asic2a; amiloride-sensitive cation channel 3, testis. [refseq;acc:nm_004769]	11.7907	Subtracted
		1.04115	569				Divided
12.2882		1.44818	60	High confidence	selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611]	8.48528
			63	Low confidence
		1.58009	51	High confidence	nanos (fragment). [sptrembl;acc:q8wy41]	19.4165
		3.80292	144		selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611]	8.48528	Subtracted
			225	Low confidence
		7.1283	57	High confidence	nanos (fragment). [sptrembl;acc:q8wy41]	19.4165
12.2937	Squared	1.90407	120		syntaxin 1a (neuron-specific antigen hpc-1). [swissprot;acc:q16623]	6.45653	Divided
		5.83717	406				Subtracted
12.3076	Rooted	1.27875	106	Low confidence	solute carrier family 26, member 11. [refseq;acc:nm_173626]	15.7383	Divided
		3.4307	244				Subtracted
12.3132		1.35362	80		alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [swissprot;acc:q9nvd7]	16.6674	Divided
		4.3542	189				Subtracted
12.3994		0.6538	660		amiloride-sensitive sodium channel delta-subunit (epithelial na+ channel delta subunit) (delta enac) (nonvoltage-gated sodium channel 1 delta subunit) (scned) (delta nach). [swissprot;acc:p51172]	11.7456
		1.05566	498				Divided
12.4394		0.4918	432	High confidence	secreted modular calcium-binding protein 1. [refseq;acc:nm_022137]	11.9476	Subtracted
			708	Low confidence
		1.04116	372	High confidence			Divided
			568	Low confidence
12.4629		0.0399	488	High confidence	pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790]	12.5028	Subtracted
		1.0032	487				Divided
12.49		3.94968	22		succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor (cybs) (succinate-ubiquinone reductase membrane anchor subunit) (qps2) (cii-4) (succinate dehydrogenase complex subunit d) (succinate-ubiquinone oxidoreductase cytochrome b small subunit). [swissprot;acc:o14521]	3.16228
		9.32772	34				Subtracted
12.5026		1.0586	368		40s ribosomal protein s28. [swissprot;acc:p25112]	13.5612
		1.08467	285				Divided
12.5624	Squared	7.83299	41		dystrophin. [swissprot;acc:p11532]	98.4011
		85.8387	290				Subtracted
12.5698	Rooted	2.29492	17	Low confidence	ptd016 protein. [refseq;acc:nm_016125]	5.47723	Divided
			30	High confidence
		7.09257		Low confidence			Subtracted
			58	High confidence
12.6095		1.43581	63		dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]	18.1049	Divided
		5.4954	85				Subtracted
12.6188	Squared	2.13426	99	Low confidence	zona pellucida sperm-binding protein 3 precursor (zona pellucida glycoprotein zp3) (zona pellucida protein c) (sperm receptor) (zp3a/zp3b). [swissprot;acc:p21754]	26.9318	Divided
		14.313	744				Subtracted
12.6735	Rooted	1.119	221		alanine-glyoxylate aminotransferase 2-like 1. [refseq;acc:nm_031279]	14.1816	Divided
		1.5081	466				Subtracted
12.7302	Squared	2.12849	101		b24o18.3 (pom121 membrane glycoprotein (rat homolog)-like 2). [sptrembl;acc:q96kw2]	27.0961	Divided
		14.3659	743				Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.