Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered green Gene Value Type network_comparison Rank Interaction Map description Network Comparison Type red
Results: HTML CSV LaTeX Showing element 501 to 550 of 38536 in total
Filtered  : 0
Network Comparison Type  : Divided
green
Value Type
network_comparison
Rank
Interaction Map
description
red
12.7411 Rooted 1.73139 31 Low confidence synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296] 7.3589
12.753 1.24434 120 selenoprotein t. [swissprot;acc:q9nzj3] 10.2488
12.7728 1.04784 540 mitochondrial carrier protein mgc4399. [refseq;acc:nm_032315] 12.1897
12.8712 1.02033 697 cln3 protein (battenin) (batten disease protein). [swissprot;acc:q13286] 13.1329
12.8903 1.03648 384 High confidence 60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914] 13.3606
12.9333 1.12923 205 Low confidence transcription factor dp-1 (e2f dimerization partner 1) (drtf1- polypeptide-1) (drtf1). [swissprot;acc:q14186] 14.6047
12.9538 1.41698 67 alpha 2 globin. [refseq;acc:nm_000517] 18.3553
12.9627 1.41651 68 hemoglobin gamma-a and gamma-g chains. [swissprot;acc:p02096] 18.3618
12.9659 1.41635 69 myoglobin. [swissprot;acc:p02144] 18.3642
13.034 1.22258 124 High confidence f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755] 10.6611
13.1421 Squared 1.08499 390 alpha-nac protein. [sptrembl;acc:q9h009] 12.1126
13.1443 1.08826 387 nascent-polypeptide-associated complex alpha polypeptide. [refseq;acc:nm_005594] 12.0783
13.1909 Rooted 1319090 93 cab2. [refseq;acc:nm_033419] 0.00001
13.3054 1.17432 147 Low confidence cg4853 gene product. [refseq;acc:nm_145313] 15.6248
13.373 1.02724 433 High confidence rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150] 13.7373
13.4012 1.01149 760 Low confidence cyclin h (mo15-associated protein) (p37) (p34). [swissprot;acc:p51946] 13.5552
13.448 Squared 2.55866 83 mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932] 34.4089
13.4716 Rooted 1.15887 164 piwi-like 2; miwi like. [refseq;acc:nm_018068] 15.6118
13.5207 1.38596 69 High confidence cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] 18.7392
13.5494 1.11829 224 Low confidence protein transport protein sec24c (sec24-related protein c). [swissprot;acc:p53992] 15.1522
13.5647 1.80277 40 High confidence cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336] 24.454
13.6105 1.35766 76 testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562] 10.025
13.6518 1.11204 344 Low confidence espin. [refseq;acc:nm_031475] 15.1813
13.7156 1.08451 405 poly(rc)-binding protein 2 (alpha-cp2) (hnrnp-e2). [swissprot;acc:q15366] 12.6468
13.7907 1.10039 358 estrogen-related receptor gamma (estrogen receptor related protein 3) (err gamma-2). [swissprot;acc:o75454] 15.1752
13.8207 Squared 1.38377 218 High confidence testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562] 19.1247
13.8963 Rooted 1.03439 394 tbp-associated factor 9l; neuronal cell death-related protein; taf9-like rna polymerase ii, tata box binding protein (tbp)-associated factor, 31 kd; neuronal cell death-related gene in neuron-7; transcription associated factor tafii31l; transcription initiation factor iid, 31kd subunit. [refseq;acc:nm_015975] 13.4343
13.9084 1.17928 143 importin 4. [refseq;acc:nm_024658] 16.4019
13.9284 1.12149 232 gaba-a receptor-associated protein. [sptrembl;acc:q9by60] 15.6205
14.0846 1.2322 121 myosin vi. [swissprot;acc:q9um54] 17.3551
123 Low confidence
14.1963 1.09552 267 High confidence transcription factor mafk (erythroid transcription factor nf-e2 p18 subunit). [swissprot;acc:o60675] 12.9585
14.2577 1.09465 268 transcription factor mafg (v-maf musculoaponeurotic fibrosarcoma oncogene homolog g) (hmaf). [swissprot;acc:o15525] 13.0249
14.3004 1.13534 195 Low confidence adapter-related protein complex 1 sigma 1b subunit (sigma-adaptin 1b) (adaptor protein complex ap-1 sigma-1b subunit) (golgi adaptor ha1/ap1 adaptin sigma-1b subunit) (clathrin assembly protein complex 1 sigma- 1b small chain) (sigma 1b subunit of ap-1 clathrin) (dc22). [swissprot;acc:p56377] 16.2358
14.3151 1.11026 246 High confidence maguk p55 subfamily member 2 (mpp2 protein) (discs, large homolog 2). [swissprot;acc:q14168] 12.8935
14.3181 1.02893 637 Low confidence dynactin 1 (150 kda dynein-associated polypeptide) (dp-150) (dap-150) (p150-glued) (p135). [swissprot;acc:q14203] 14.7323
14.3236 1.12835 208 stromal membrane-associated protein; stromal membrane-associated protein smap1a. [refseq;acc:nm_021940] 16.162
14.3333 Measured 1.3721 121 High confidence 4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404] 19.6667
14.4058 Rooted 1.82337 25 Low confidence potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281] 7.90063
39 High confidence
14.4887 1.35259 84 Low confidence dynamin-like 120 kda protein, mitochondrial precursor (optic atrophy 1 gene protein). [swissprot;acc:o60313] 19.5973
14.4914 1.16292 159 helicase/primase complex protein. [refseq;acc:nm_138336] 16.8523
14.5086 1.05434 332 High confidence basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811] 15.297
14.5738 1.26912 115 estrogen-related receptor gamma (estrogen receptor related protein 3) (err gamma-2). [swissprot;acc:o75454] 18.4959
14.6565 1.08063 408 Low confidence glycerol kinase (ec 2.7.1.30) (atp:glycerol 3-phosphotransferase) (glycerokinase) (gk). [swissprot;acc:p32189] 15.8382
14.6595 1.07978 410 glycerol kinase, testis specific 1 (ec 2.7.1.30) (atp:glycerol 3- phosphotransferase) (glycerokinase) (gk). [swissprot;acc:q14409] 15.829
14.6672 1.07735 419 glycerol kinase, testis specific 2 (ec 2.7.1.30) (atp:glycerol 3- phosphotransferase) (glycerokinase) (gk). [swissprot;acc:q14410] 15.8017
14.6994 1.16915 152 f-actin capping protein alpha-2 subunit (capz alpha-2). [swissprot;acc:p47755] 17.1858
14.7003 1.05005 349 High confidence guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8] 15.4361
14.7392 1.67654 45 elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897] 8.79142

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/