MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 2530 to 2579 of 29840 in total

Interaction Map  : High confidence

Rank	description	Value Type	Network Comparison Type	Filtered	red	green	network_comparison
159	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	Ranked	Divided	0	5813.32	6706.32	1.15361
	dihydrofolate reductase (ec 1.5.1.3). [swissprot;acc:p00374]		Subtracted		11971.7	10412.4	1559.3
	doc-1 related protein (doc-1r). [swissprot;acc:o75956]			1	312	284	28
	huntingtin interacting protein 1 related (hip1-related) (hip 12). [swissprot;acc:o75146]	Squared			76296.4	58801.6	17494.8
	lipocalin-interacting membrane receptor. [refseq;acc:nm_018113]	Measured	Divided	0	734.025	574.372	1.27796
	mto1 protein homolog (cgi-02). [swissprot;acc:q9y2z2]		Subtracted		1002.2	793.818	208.382
	myosin heavy chain, cardiac muscle beta isoform (myhc-beta). [swissprot;acc:p12883]			1	9035	7279.6	1755.4
	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]	Rooted	Divided	0	52.3183	44.8382	1.16682
	myosin vi. [swissprot;acc:q9um54]		Subtracted		17.3551	14.0846	3.2705
	necdin. [swissprot;acc:q99608]	Measured	Divided	1	23693.7	18263	1.29736
	regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6]	Ranked			249.663	298.263	1.19466
	rna-binding protein. [refseq;acc:nm_019027]	Rooted			52.7642	61.9019	1.17318
	septin 6. [swissprot;acc:q14141]	Squared			88953.6	124854	1.40359
	ubiquitin activating enzyme e1-like protein. [refseq;acc:nm_006395]	Rooted	Subtracted		113.983	101.979	12.004
	udp-glucuronosyltransferase 2b4 precursor, microsomal (ec 2.4.1.17) (udpgt) (hyodeoxycholic acid) (hlug25) (udpgth-1). [swissprot;acc:p06133]	Squared	Divided	0	6123.28	3763.18	1.62716
160	apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576]	Rooted		1	52.7642	61.9019	1.17318
	atp-dependent dna helicase ii, 70 kda subunit (lupus ku autoantigen protein p70) (ku70) (70 kda subunit of ku antigen) (thyroid-lupus autoantigen) (tlaa) (ctc box binding factor 75 kda subunit) (ctcbf) (ctc75). [swissprot;acc:p12956]		Subtracted	0	21.8452	18.5801	3.2651
	bystin. [swissprot;acc:q13895]	Measured			2930.88	3135.76	204.88
	ccr4-not transcription complex, subunit 7 (ccr4-associated factor 1) (caf1) (btg1 binding factor 1). [swissprot;acc:q9uiv1]	Ranked	Divided		11732	13530.6	1.15331
	dj756n5.1.1 (continues in em:al133324 as dj1161h23.3) (fragment). [sptrembl;acc:q9h430]	Measured	Subtracted	1	9035	7279.6	1755.4
	e1a binding protein p400; p400 swi2/snf2-related protein; cagh32 protein; trinucleotide repeat containing 12. [refseq;acc:nm_015409]	Rooted	Divided	0	34.3021	29.5305	1.16158
	estradiol 17 beta-dehydrogenase 1 (ec 1.1.1.62) (17-beta-hsd 1) (placental 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-hsd) (e2dh). [swissprot;acc:p14061]	Squared	Subtracted		14907.5	15522.7	615.2
	glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]		Divided		6123.28	3763.18	1.62716
	guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471]	Ranked		1	249.663	298.263	1.19466
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	Squared			173408	242989	1.40126
	huntingtin interacting protein c. [refseq;acc:nm_012272]	Measured		0	1653.74	1296.38	1.27566
	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	Rooted	Subtracted	1	43.4291	31.7159	11.7132
	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]	Measured	Divided		23693.7	18263	1.29736
	neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	Ranked	Subtracted		312	284	28
	putative nucleoside diphosphate kinase (ec 2.7.4.6) (ndk) (ndp kinase). [swissprot;acc:o60361]			0	10060.2	11616.4	1556.2
	t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368]	Squared		1	42788.3	60162.6	17374.3
161	60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	Rooted		0	19.3128	16.0484	3.2644
	adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]	Squared			50.7031	647.816	597.113
	adp-ribosylation factor 3. [swissprot;acc:p16587]	Rooted	Divided		14.8377	17.2252	1.16091
	cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936]	Ranked			5781.93	6660.63	1.15197
	glutamine synthetase (ec 6.3.1.2) (glutamate--ammonia ligase). [swissprot;acc:p15104]	Measured	Subtracted		1230.54	1026.18	204.36
	glycine cleavage system h protein, mitochondrial precursor. [swissprot;acc:p23434]		Divided		903.767	1152.06	1.27473
	homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483]	Squared		1	173408	242989	1.40126
	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]	Measured			23693.7	18263	1.29736
	myosin heavy chain, skeletal muscle, extraocular (myhc-eo). [swissprot;acc:q9ukx3]		Subtracted		9035	7279.6	1755.4
	neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]	Ranked			312	284	28
	ns1-associated protein 1. [refseq;acc:nm_006372]	Rooted	Divided		52.7642	61.9019	1.17318
	potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183]		Subtracted		43.4519	31.7522	11.6997
	protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236]	Ranked		0	15245.4	16788.5	1543.1
	rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736]		Divided	1	249.663	298.263	1.19466
	trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase (ec 2.1.1.61). [swissprot;acc:o75648]	Squared	Subtracted		52591.3	69845.1	17253.8
	udp-glucuronosyltransferase 2b10 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:p36537]		Divided	0	6123.28	3763.18	1.62716
162	60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	Measured	Subtracted		1753.85	1956.36	202.51
	aquaporin-cd (aqp-cd) (water channel protein for renal collecting duct) (adh water channel) (aquaporin 2) (collecting duct water channel protein) (wch-cd). [swissprot;acc:p41181]	Rooted			21.0926	17.849	3.2436
	arsenical pump-driving atpase (ec 3.6.3.16) (arsenite-translocating atpase) (arsenical resistance atpase) (arsenite-transporting atpase) (arsa) (asna-i). [swissprot;acc:o43681]	Squared			1662.68	2253.78	591.1

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.