MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Value Type	Interaction Map	Gene	green	Filtered	Rank	description	Network Comparison Type	network_comparison	red

Results: HTML CSV LaTeX

Showing element 2480 to 2529 of 3228 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided

green	Rank	description	network_comparison	red
224.699	1238	keratin associated protein 4.3 (fragment). [sptrembl;acc:q9byr4]	1.02437	219.354
	1239	keratin associated protein 2-4; keratin associated protein 2.4. [refseq;acc:nm_033184]
	1243	keratin associated protein 1.5. [refseq;acc:nm_031957]
	1245	keratin, ultra high-sulfur matrix protein b (uhs keratin b) (uhs kerb). [swissprot;acc:o75690]
	1246	keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [swissprot;acc:p26371]
	1248	keratin associated protein 4.4. [refseq;acc:nm_032524]
	1256	keratin associated protein 1-3; keratin associated protein 1.3. [refseq;acc:nm_030966]
224.7	1240	keratin associated protein 4-14; keratin associated protein 4.14. [refseq;acc:nm_033059]
	1241	keratin associated protein 4.9 (fragment). [sptrembl;acc:q9byq8]
	1242	keratin associated protein 4-12; keratin associated protein 4.12. [refseq;acc:nm_031854]
	1244	star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [swissprot;acc:p59095]
	1247	star-related lipid transfer protein 5 (stard5) (start domain- containing protein 5). [swissprot;acc:q9nsy2]
	1249	alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [swissprot;acc:q9nvd7]
	1250	pinch protein (particularly interesting new cys-his protein) (lim and senescent cell antigen-like domains 1). [swissprot;acc:p48059]
	1251	integrin-linked protein kinase 1 (ec 2.7.1.-) (ilk-1) (59 kda serine/threonine protein kinase) (p59ilk). [swissprot;acc:q13418]
	1252	star-related lipid transfer protein 4 (stard4) (start domain- containing protein 4). [swissprot;acc:q96dr4]
	1253	ras suppressor protein 1 (rsu-1) (rsp-1). [swissprot;acc:q15404]
	1254	ras-gtpase-activating protein binding protein 1 (gap sh3-domain binding protein 1) (g3bp-1). [swissprot;acc:q13283]
	1255	ras-gtpase-activating protein binding protein 2 (gap sh3-domain binding protein 2) (g3bp-2). [swissprot;acc:q9un86]
	1257	espin. [refseq;acc:nm_031475]
	1258	cytochrome p450 2d6 (ec 1.14.14.1) (cypiid6) (p450-db1) (debrisoquine 4-hydroxylase). [swissprot;acc:p10635]
	1259	pleckstrin homology domain containing, family c (with ferm domain) member 1; mitogen inducible 2; kindlin 2. [refseq;acc:nm_006832]
	1260	lim and senescent cell antigen-like domains 2; ilk-binding protein. [refseq;acc:nm_017980]
	1261	d(4) dopamine receptor (d(2c) dopamine receptor). [swissprot;acc:p21917]
224.723	1235	keratin associated protein 9-4; keratin associated protein 9.4. [refseq;acc:nm_033191]	1.02447	219.356
224.767	1565	eukaryotic translation initiation factor 3 subunit 11 (eif-3 p25) (eif3k) (muscle specific gene m9 protein) (ptd001) (hspc029) (arg134). [swissprot;acc:q9ubq5]	1.01646	221.128
	1566	erythroid differentiation and denucleation factor 1. [swissprot;acc:o60584]
	1567	bardet-biedl syndrome 7 protein isoform a; bbs2-like 1. [refseq;acc:nm_176824]
	1568	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
	1569	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]
	1570	protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]
	1571	eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]
	1572	putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]
224.869	2256	seven in absentia homolog 2. [refseq;acc:nm_005067]	1.00592	223.546
224.902	1612	enthoprotin; epsin 4; clathrin interacting protein localized in the trans-golgi region. [refseq;acc:nm_014666]	1.0157	221.426
224.943	2246	mitochondrial ribosomal protein l18. [refseq;acc:nm_014161]	1.0061	223.58
224.958	859	60s ribosomal protein l39. [swissprot;acc:p02404]	1.04031	234.025
	860	60s ribosomal protein l18a. [swissprot;acc:q02543]
	861	40s ribosomal protein s19. [swissprot;acc:p39019]
	862	60s ribosomal protein l31. [swissprot;acc:p12947]
224.989	2112	dna-directed rna polymerases iii 12.5 kda polypeptide (ec 2.7.7.6) (rna polymerase iii c11 subunit) (hsc11p) (hrpc11) (my010 protein). [swissprot;acc:q9y2y1]	1.00705	223.415
225.005	2234	seven in absentia homolog 1. [refseq;acc:nm_003031]	1.00625	223.608
225.008	2070	rac gtpase activating protein 1; gtpase activating protein. [refseq;acc:nm_013277]	1.0081	223.199
225.163	1689	dead-box protein 4 (vasa homolog). [swissprot;acc:q9nqi0]	1.01383	228.277
225.164	2543	tubulin tyrosine ligase-like protein hottl (hqp0207). [swissprot;acc:q9y4r7]	1.00195	224.726
225.17	1893	gdp-mannose pyrophosphorylase b isoform 1; mannose-1-phosphate guanylyltransferase; amphoterin induced gene 3. [refseq;acc:nm_013334]	1.01045	222.842
	1894	gdp-mannose pyrophosphorylase a; mannose-1-phosphate guanylyltransferase (gdp). [refseq;acc:nm_013335]
225.185	1620	transcription initiation factor iib (general transcription factor tfiib) (s300-ii). [swissprot;acc:q00403]	1.01521	228.611
	1621	thyroid receptor interacting protein 3 (trip-3) (fragment). [swissprot;acc:q15649]
	1622	nhp2-like protein 1 (high mobility group-like nuclear protein 2 homolog 1) ([u4/u6.u5] tri-snrnp 15.5 kda protein) (otk27). [swissprot;acc:p55769]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.