Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1625 to 1674 of 3228 in total 
Value Type	Measured
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	green	network_comparison	
1625	zinc finger protein 277. [source:swissprot;acc:q9nrm2]	4102.1	4392.15	1.07071	
1626	phospholipase d2 (ec 3.1.4.4) (pld 2) (choline phosphatase 2) (phosphatidylcholine-hydrolyzing phospholipase d2) (pld1c) (hpld2). [source:swissprot;acc:o14939]	6157.13	6591.53	1.07055	
1627	6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [source:swissprot;acc:o95336]	6038.46	6463.9	1.07046	
1628	glycine cleavage system h protein, mitochondrial precursor. [source:swissprot;acc:p23434]	5920.55	6337.28	1.07039	
1629	dimeric dihydrodiol dehydrogenase; 3-deoxyglucosone reductase. [source:refseq;acc:nm_014475]	6158.32	6590.99	1.07026	
1630	c-terminal binding protein 2 (ctbp2). [source:swissprot;acc:p56545]	9903.22	9253.79	1.07018	
1631	brachyury protein (t protein). [source:swissprot;acc:o15178]	6179.59	6613.15	1.07016	
1632	t-box transcription factor tbx19 (t-box protein 19). [source:swissprot;acc:o60806]	6179.59	6613.15	1.07016	
1633	b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [source:refseq;acc:nm_181844]	9899.79	9251.2	1.07011	
1634	pas domain containing serine/threonine kinase; pas-serine/threonine kinase. [source:refseq;acc:nm_015148]	9899.73	9251.16	1.07011	
1635	b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [source:swissprot;acc:p41182]	9899.73	9251.16	1.07011	
1636	zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [source:swissprot;acc:o43623]	9899.73	9251.16	1.07011	
1637	proteasome subunit alpha type 6 (ec 3.4.25.1) (proteasome iota chain) (macropain iota chain) (multicatalytic endopeptidase complex iota chain) (27 kda prosomal protein) (pros-27) (p27k). [source:swissprot;acc:p34062]	6112.4	6540.73	1.07008	
1638	c-terminal binding protein 1 (ctbp1). [source:swissprot;acc:q13363]	9895.77	9248.18	1.07002	
1639	putative inorganic polyphosphate/atp-nad kinase (ec 2.7.1.23) (poly(p)/atp nad kinase). [source:swissprot;acc:o95544]	5939.71	6354.79	1.06988	
1640	adenylosuccinate lyase (ec 4.3.2.2) (adenylosuccinase) (asl) (asase). [source:swissprot;acc:p30566]	7444.28	7964	1.06981	
1641	ba271b5.1 (similar to ribosomal protein s7). [source:sptrembl;acc:q9h1s9]	5782.92	6186.39	1.06977	
1642	40s ribosomal protein s7 (s8). [source:swissprot;acc:p23821]	5782.92	6186.39	1.06977	
1643	26s proteasome-associated pad1 homolog. [source:refseq;acc:nm_005805]	5782.92	6186.39	1.06977	
1644	apolipoprotein b-100 precursor (apo b-100) [contains: apolipoprotein b-48 (apo b-48)]. [source:swissprot;acc:p04114]	5782.92	6186.39	1.06977	
1645	proto-oncogene tyrosine-protein kinase fes/fps (ec 2.7.1.112) (c-fes). [source:swissprot;acc:p07332]	6079.19	6503.12	1.06973	
1646	molybdenum cofactor synthesis protein 2 large subunit (molybdopterin synthase large subunit) (mpt synthase large subunit) (mocs2b) (moco1- b). [source:swissprot;acc:o96007]	6079.19	6503.12	1.06973	
1647	anaphase-promoting complex subunit 10; anaphase-promoting complex 10. [source:refseq;acc:nm_014885]	6079.19	6503.12	1.06973	
1648	60s ribosomal protein l29 (cell surface heparin binding protein hip). [source:swissprot;acc:p47914]	6079.19	6503.12	1.06973	
1649	proto-oncogene tyrosine-protein kinase fer (ec 2.7.1.112) (p94-fer) (c-fer). [source:swissprot;acc:p16591]	6079.19	6503.12	1.06973	
1650	molybdenum cofactor synthesis protein 3 (molybdopterin synthase sulfurylase) (mpt synthase sulfurylase). [source:swissprot;acc:o95396]	6079.19	6503.12	1.06973	
1651	cbf1 interacting corepressor. [source:refseq;acc:nm_004882]	5944.24	6358.1	1.06962	
1652	evolutionarily conserved g-patch domain containing. [source:refseq;acc:nm_018025]	5944.24	6358.1	1.06962	
1653	transcription factor mafg (v-maf musculoaponeurotic fibrosarcoma oncogene homolog g) (hmaf). [source:swissprot;acc:o15525]	7433.73	7950.61	1.06953	
1654	transcription factor maff (v-maf musculoaponeurotic fibrosarcoma oncogene homolog f) (u-maf). [source:swissprot;acc:q9ulx9]	7433.73	7950.61	1.06953	
1655	40s ribosomal protein s26. [source:swissprot;acc:p02383]	5488.7	5131.89	1.06953	
1656	mitochondrial import inner membrane translocase subunit tim22. [source:swissprot;acc:q9y584]	5488.7	5131.89	1.06953	
1657	atp synthase mitochondrial f1 complex assembly factor 2. [source:refseq;acc:nm_145691]	5488.7	5131.89	1.06953	
1658	transcription factor mafk (erythroid transcription factor nf-e2 p18 subunit). [source:swissprot;acc:o60675]	7433.73	7950.61	1.06953	
1659	ubiquinol-cytochrome c reductase complex 14 kda protein (ec 1.10.2.2) (complex iii subunit vi) (qp-c). [source:swissprot;acc:p14927]	5488.7	5131.89	1.06953	
1660	cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [source:refseq;acc:nm_006614]	7433.73	7950.61	1.06953	
1661	neural cell adhesion molecule l1 precursor (n-cam l1) (cd171 antigen). [source:swissprot;acc:p32004]	7433.73	7950.61	1.06953	
1662	transcription initiation factor tfiid 31 kda subunit (tafii-31) (tafii-32) (tafii32). [source:swissprot;acc:q16594]	7433.73	7950.61	1.06953	
1663	nuclear factor erythroid 2 related factor 1 (nf-e2 related factor 1) (nfe2-related factor 1) (nuclear factor, erythroid derived 2, like 1) (transcription factor 11) (transcription factor hbz17) (transcription factor lcr-f1) (locus control region-factor 1). [source:swissprot;acc:q14494]	7433.73	7950.61	1.06953	
1664	nuclear factor (erythroid-derived 2)-like 3; nf-e2-related factor 3. [source:refseq;acc:nm_004289]	7433.73	7950.61	1.06953	
1665	fatty acid-binding protein, adipocyte (afabp) (adipocyte lipid-binding protein) (albp) (a-fabp). [source:swissprot;acc:p15090]	5791.14	6193.02	1.0694	
1666	fatty acid-binding protein, epidermal (e-fabp) (psoriasis-associated fatty acid-binding protein homolog) (pa-fabp). [source:swissprot;acc:q01469]	5791.14	6193.02	1.0694	
1667	fatty acid-binding protein, brain (b-fabp) (brain lipid-binding protein) (blbp) (mammary derived growth inhibitor related). [source:swissprot;acc:o15540]	5791.14	6193.02	1.0694	
1668	wd-repeat protein 4. [source:swissprot;acc:p57081]	5791.14	6193.02	1.0694	
1669	myelin p2 protein. [source:swissprot;acc:p02689]	5791.14	6193.02	1.0694	
1670	kelch-like protein 8. [source:swissprot;acc:q9p2g9]	5791.14	6193.02	1.0694	
1671	phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [source:swissprot;acc:p11086]	5791.14	6193.02	1.0694	
1672	beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [source:refseq;acc:nm_031938]	5791.14	6193.02	1.0694	
1673	beta-carotene 15, 15'-dioxygenase; beta-carotene 15,15'-monooxygenase. [source:refseq;acc:nm_017429]	5791.14	6193.02	1.0694	
1674	fatty acid-binding protein, heart (h-fabp) (muscle fatty acid-binding protein) (m-fabp) (mammary-derived growth inhibitor) (mdgi). [source:swissprot;acc:p05413]	5791.14	6193.02	1.0694	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/