MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	Gene	network_comparison	red	Network Comparison Type	Interaction Map	Rank	description

Results: HTML CSV LaTeX

Showing element 1 to 32 of 32 in total

Rank  : 8

Filtered	Value Type	green	network_comparison	red	Network Comparison Type	Interaction Map	description
0	Measured	43	4300000	0.00001	Divided	High confidence	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
		6410	75.4118	85		Low confidence	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
		7500.75	2393.82	5106.93	Subtracted	High confidence	nucleoporin nup43 (p42). [swissprot;acc:q8nfh3]
		8770.72	1232.83	7537.89		Low confidence	zinc finger protein 277. [swissprot;acc:q9nrm2]
	Ranked	13216	1.68629	22286	Divided		homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]
			9070		Subtracted	High confidence	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
		19873	8983.6	10889.4		Low confidence	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
		21888	1.89918	11525	Divided	High confidence	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
	Squared	0.00001	159148	1.59148			ero1-like. [refseq;acc:nm_014584]
		19295.9	11098	1.73869		Low confidence	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
		61843.5	16419.5	45424	Subtracted		similar to zinc finger protein 277. [sptrembl;acc:q8wwa6]
		386144	28560	414704		High confidence	transcription initiation factor tfiid 135 kda subunit (tafii-135) (tafii135) (tafii-130) (tafii130). [swissprot;acc:o00268]
	Rooted	0.00001	360555	3.60555	Divided	Low confidence	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			905539	9.05539		High confidence	ero1-like. [refseq;acc:nm_014584]
		56.7758	15.3379	72.1137	Subtracted		nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]
		111.067	15.292	126.359		Low confidence	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]
1	Measured	339.5	3.39764	1153.5	Divided	High confidence	db83 protein. [swissprot;acc:p57088]
		5058.5	1.54317	3278		Low confidence	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]
		28492	7307	21185	Subtracted	High confidence	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]
		39358.1	6246.7	33111.4		Low confidence	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]
	Ranked	240	1.325	318	Divided		oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]
		247.246	58.226	305.472	Subtracted		thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
		322	1.49767	215	Divided	High confidence	hbs1-like. [refseq;acc:nm_006620]
		362	74	288	Subtracted		junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]
	Squared	27.2805	11.544	314.926	Divided		db83 protein. [swissprot;acc:p57088]
		6056.43	2.38136	2543.26		Low confidence	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]
		192141	85915	106226	Subtracted		mitochondrial solute carrier protein. [refseq;acc:nm_145305]
		354894	104591	250303		High confidence	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]
	Rooted	18.4255	1.84327	33.9632	Divided		db83 protein. [swissprot;acc:p57088]
		45.9728	18.8343	27.1385	Subtracted	Low confidence	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]
		47.6922	1.49674	31.8641	Divided		thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
		168.796	23.245	145.551	Subtracted	High confidence	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [swissprot;acc:q9h999]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.