Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 230 to 279 of 8289 in total
Value Type  : Measured
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Interaction Map
red
green
network_comparison
115 melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] Low confidence 11285.3 10318.5 1.0937
116 hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04] High confidence 21185 28492 1.34491
117 melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] Low confidence 11285.3 10318.5 1.0937
pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23] High confidence 21185 28492 1.34491
118 necdin. [swissprot;acc:q99608] Low confidence 11285.3 10318.5 1.0937
pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [swissprot;acc:q9h999] High confidence 21185 28492 1.34491
119 melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] Low confidence 11285.3 10318.5 1.0937
mitochondrial solute carrier protein. [refseq;acc:nm_145305] High confidence 21185 28492 1.34491
120 high-mobility group 20b; sox-like transcriptional factor; swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e, member 1-related. [refseq;acc:nm_006339] 5136.78 6895.98 1.34247
melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] Low confidence 11285.3 10318.5 1.0937
121 melanoma antigen, family b, 6. [refseq;acc:nm_173523]
transcription factor jun-b. [swissprot;acc:p17275] High confidence 5579.18 7488.4 1.3422
122 high-mobility group 20a. [refseq;acc:nm_018200] 5140.14 6893.53 1.34112
melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] Low confidence 11285.3 10318.5 1.0937
123 cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936] High confidence 24260.3 18172.1 1.33503
melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] Low confidence 11285.3 10318.5 1.0937
124 melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8] High confidence 24255.7 18168.9 1.33501
125 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732] Low confidence 11285.3 10318.5 1.0937
microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492] High confidence 24255.7 18168.9 1.33501
126 cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326] 24250 18164.9 1.33499
melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365] Low confidence 11285.3 10318.5 1.0937
127 melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
transcription factor jun-d. [swissprot;acc:p17535] High confidence 5638.2 7523.39 1.33436
128 luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019] 4355.61 5810.82 1.3341
melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363] Low confidence 11285.3 10318.5 1.0937
129 luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032] High confidence 4358.13 5811.49 1.33348
melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366] Low confidence 11285.3 10318.5 1.0937
130 forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457] High confidence 2234.68 2978.53 1.33287
melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1] Low confidence 11285.3 10318.5 1.0937
131 forkhead box protein p1 (hspc215). [swissprot;acc:q9h334] High confidence 2234.73 2978.57 1.33285
trophinin. [swissprot;acc:q12816] Low confidence 11285.3 10318.5 1.0937
132 dual specificity mitogen-activated protein kinase kinase 4 (ec 2.7.1.-) (map kinase kinase 4) (jnk activating kinase 1) (c-jun n- terminal kinase kinase 1) (jnkk) (sapk/erk kinase 1) (sek1). [swissprot;acc:p45985] 5948.88 5441.83 1.09318
forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1] High confidence 2236.61 2980.35 1.33253
133 gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278] 23421.5 17580.4 1.33225
ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464] Low confidence 7013 7662.77 1.09265
134 ba127l20.1 (novel glutathione-s-transferase). [sptrembl;acc:q9h4y5] 6670.21 7286.66 1.09242
gaba-a receptor-associated protein. [sptrembl;acc:q9by60] High confidence 21785.2 16426.1 1.32626
135 apg3p; pc3-96 protein. [refseq;acc:nm_022488]
high-mobility group 20a. [refseq;acc:nm_018200] Low confidence 7248.24 7916.96 1.09226
136 nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952] High confidence 3620.77 4763.34 1.31556
ribosomal protein s6 kinase, 52kda, polypeptide 1; ribosomal protein s6 kinase, 52kd, polypeptide 1. [refseq;acc:nm_012424] Low confidence 7020.48 7667.34 1.09214
137 ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511] High confidence 3620.77 4763.34 1.31556
t-box transcription factor tbx19 (t-box protein 19). [swissprot;acc:o60806] Low confidence 6139.6 6699.58 1.09121
138 glutathione transferase omega 1 (ec 2.5.1.18) (gsto 1-1). [swissprot;acc:p78417] 6709 7313.38 1.09008
kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592] High confidence 2755.15 2094.3 1.31555
139 60s ribosomal protein l37a. [swissprot;acc:p12751] Low confidence 5762.4 6277.91 1.08946
potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183] High confidence 2759.61 2099.49 1.31442
140 kv channel interacting protein 2 isoform 4; a-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit. [refseq;acc:nm_173193] 2760.28 2100.27 1.31425

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/