MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Value Type	Gene	Hugo	Interaction Map	description	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 223 to 272 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Value Type	Hugo	description
2811	Squared	VEGFB	vascular endothelial growth factor b precursor (vegf-b) (vegf related factor) (vrf). [swissprot;acc:p49765]
	Rooted
2812	Measured	MOBKL2A	mob-lak. [refseq;acc:nm_130807]
	Ranked
	Squared
	Rooted
2813	Measured	HDAC3	histone deacetylase 3 (hd3) (rpd3-2). [swissprot;acc:o15379]
	Ranked
	Squared
	Rooted
2814	Measured	SPSB1	spry domain-containing socs box protein ssb-1. [refseq;acc:nm_025106]
	Ranked
	Squared
	Rooted
2815	Measured	NMUR1	g protein-coupled receptor 66. [refseq;acc:nm_006056]
	Ranked
	Squared
	Rooted
2816	Measured	TIGD1	tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]
	Ranked
	Squared
	Rooted
2817	Measured	TBCA	tubulin-specific chaperone a (tubulin-folding cofactor a) (cfa) (tcp1-chaperonin cofactor a). [swissprot;acc:o75347]
	Ranked
	Squared
	Rooted
2818	Measured	UGT2B7	udp-glucuronosyltransferase 2b7 precursor, microsomal (ec 2.4.1.17) (udpgt) (3,4-catechol estrogen specific) (udpgth-2). [swissprot;acc:p16662]
	Ranked
	Squared
	Rooted
2819	Measured	no value	udp-glucuronosyltransferase 2b11 precursor, microsomal (ec 2.4.1.17) (udpgt). [swissprot;acc:o75310]
	Ranked
	Squared
	Rooted
2820	Measured		peregrin (bromodomain and phd finger-containing protein 1) (br140 protein). [swissprot;acc:p55201]
	Ranked
	Squared
	Rooted
2821	Measured	ATP6V0E2	vacuolar proton-atpase subunit. [sptrembl;acc:q8nhe4]
	Ranked
	Squared
	Rooted
2822	Measured	SLC30A1	zinc transporter 1 (znt-1). [swissprot;acc:q9y6m5]
	Ranked
	Squared
	Rooted
2823	Measured	NFRKB	nuclear factor related to kappa b binding protein. [refseq;acc:nm_006165]
	Ranked
	Squared
	Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.