MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	green	red	network_comparison	Gene	Interaction Map	Network Comparison Type	Rank	description

Results: HTML CSV LaTeX

Showing element 1 to 32 of 32 in total

Rank  : 8

Filtered	Value Type	green	red	network_comparison	Interaction Map	Network Comparison Type	description
0	Measured	43	0.00001	4300000	High confidence	Divided	synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
		6410	85	75.4118	Low confidence		ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
		7500.75	5106.93	2393.82	High confidence	Subtracted	nucleoporin nup43 (p42). [swissprot;acc:q8nfh3]
		8770.72	7537.89	1232.83	Low confidence		zinc finger protein 277. [swissprot;acc:q9nrm2]
	Ranked	13216	22286	1.68629		Divided	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]
				9070	High confidence	Subtracted	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
		19873	10889.4	8983.6	Low confidence		ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
		21888	11525	1.89918	High confidence	Divided	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
	Squared	0.00001	1.59148	159148			ero1-like. [refseq;acc:nm_014584]
		19295.9	1.73869	11098	Low confidence		ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
		61843.5	45424	16419.5		Subtracted	similar to zinc finger protein 277. [sptrembl;acc:q8wwa6]
		386144	414704	28560	High confidence		transcription initiation factor tfiid 135 kda subunit (tafii-135) (tafii135) (tafii-130) (tafii130). [swissprot;acc:o00268]
	Rooted	0.00001	3.60555	360555	Low confidence	Divided	homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
			9.05539	905539	High confidence		ero1-like. [refseq;acc:nm_014584]
		56.7758	72.1137	15.3379		Subtracted	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]
		111.067	126.359	15.292	Low confidence		nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]
1	Measured	339.5	1153.5	3.39764	High confidence	Divided	db83 protein. [swissprot;acc:p57088]
		5058.5	3278	1.54317	Low confidence		phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]
		28492	21185	7307	High confidence	Subtracted	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]
		39358.1	33111.4	6246.7	Low confidence		deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]
	Ranked	240	318	1.325		Divided	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]
		247.246	305.472	58.226		Subtracted	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
		322	215	1.49767	High confidence	Divided	hbs1-like. [refseq;acc:nm_006620]
		362	288	74		Subtracted	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]
	Squared	27.2805	314.926	11.544		Divided	db83 protein. [swissprot;acc:p57088]
		6056.43	2543.26	2.38136	Low confidence		phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]
		192141	106226	85915		Subtracted	mitochondrial solute carrier protein. [refseq;acc:nm_145305]
		354894	250303	104591	High confidence		deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]
	Rooted	18.4255	33.9632	1.84327		Divided	db83 protein. [swissprot;acc:p57088]
		45.9728	27.1385	18.8343	Low confidence	Subtracted	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]
		47.6922	31.8641	1.49674		Divided	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
		168.796	145.551	23.245	High confidence	Subtracted	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [swissprot;acc:q9h999]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.