Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison

Results: HTML CSV LaTeX

Showing element 2182 to 2231 of 14920 in total

Network Comparison Type

: Divided
Interaction Map

: High confidence

Rank	description	Value Type	Filtered	red	green	network_comparison
273	sorcin (22 kda protein) (cp-22) (v19). [swissprot;acc:p30626]	Measured	0	1410.81	1582.65	1.1218
	vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670]	Rooted		24.598	26.8697	1.09235
	wiskott-aldrich syndrome protein family member 3 (wasp-family protein member 3) (verprolin homology domain-containing protein 3). [swissprot;acc:q9upy6]	Ranked		12748.1	11770.9	1.08302
274	60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	Squared		4214.44	5226.4	1.24012
	brain protein 16. [refseq;acc:nm_016458]	Measured		2155.75	2418.14	1.12172
	chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286]	Measured	1	3119.98	2579.49	1.20953
	disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	Ranked	0	10432.4	11298.4	1.08301
	grb2-related adaptor protein 2 (gads protein) (growth factor receptor binding protein) (grblg) (grf40 adaptor protein) (grf-40) (grb-2-like protein) (grb2l) (grbx) (p38) (hematopoietic cell-associated adaptor protein grpl) (adapter protein grid) (sh3-sh2-sh3 adaptor mona). [swissprot;acc:o75791]	Rooted	1	66.1063	74.1068	1.12102
	nadph-cytochrome p450 reductase (ec 1.6.2.4) (cpr) (p450r). [swissprot;acc:p16435]	Ranked		241.373	267.352	1.10763
	rev1-like; rev1 protein; rev1 (yeast homolog)- like. [refseq;acc:nm_016316]	Squared		16120.1	20665.7	1.28198
	testis-specific chromodomain protein y protein 2. [swissprot;acc:q9y6f7]	Rooted	0	32.8979	30.1206	1.09221
275	ccaat displacement protein (cdp) (cut-like 1). [swissprot;acc:p39880]	Rooted	1	66.1048	74.0977	1.12091
	cholinephosphate cytidylyltransferase b (ec 2.7.7.15) (phosphorylcholine transferase b) (ctp:phosphocholine cytidylyltransferase b) (ct b) (cct b) (cct-beta). [swissprot;acc:q9y5k3]	Ranked	1	241.373	267.352	1.10763
	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]	Ranked	0	10783	11674.1	1.08264
	pnas-18. [sptrembl;acc:q9bzu3]	Squared	0	14643.9	11814.6	1.23947
	protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873]	Squared	1	16120.1	20665.7	1.28198
	regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795]	Measured	1	3119.98	2579.49	1.20953
	swi/snf-related matrix-associated actin-dependent regulator of chromatin c2 isoform a; mammalian chromatin remodeling complex brg1-associated factor 170; chromatin remodeling complex baf170 subunit; swi3-like protein; swi/snf complex 170 kda subunit. [refseq;acc:nm_003075]	Measured	0	717.401	804.725	1.12172
	testis-specific chromodomain y protein 1. [swissprot;acc:q9y6f8]	Rooted	0	32.8937	30.117	1.0922
276	60s ribosomal protein l32. [swissprot;acc:p02433]	Ranked	1	241.13	266.969	1.10716
	60s ribosomal protein l9. [swissprot;acc:p32969]	Ranked	0	10741.6	9922.33	1.08257
	60s ribosomal protein l9. [swissprot;acc:p32969]	Rooted		26.3707	28.8011	1.09216
	apoptosis inhibitor fksg2. [swissprot;acc:q9hau6]	Measured		10817.1	12125.1	1.12092
	cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551]	Squared		14470.6	11676.7	1.23927
	homeobox protein cux-2 (cut-like 2) (fragment). [swissprot;acc:o14529]	Rooted	1	66.1046	74.0964	1.1209
	protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22]	Squared		16120.1	20665.7	1.28198
	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]	Measured		3119.98	2579.49	1.20953
277	40s ribosomal protein s29. [swissprot;acc:p30054]	Ranked		241.849	267.642	1.10665
	60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	Ranked	0	11096.8	10251.6	1.08245
	adenylosuccinate synthase-like 1. [refseq;acc:nm_152328]	Rooted		24.1033	22.0791	1.09168
	disks large-associated protein 2 (dap-2) (sap90/psd-95-associated protein 2) (sapap2) (psd-95/sap90 binding protein 2) (fragment). [swissprot;acc:q9p1a6]	Measured		870.93	975.647	1.12024
	purine nucleoside phosphorylase (ec 2.4.2.1) (inosine phosphorylase) (pnp). [swissprot;acc:p00491]	Squared		21885.1	17682.1	1.2377
	regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081]	Measured	1	3119.98	2579.49	1.20953
	ribosomal protein s6 kinase, 52kda, polypeptide 1; ribosomal protein s6 kinase, 52kd, polypeptide 1. [refseq;acc:nm_012424]	Rooted		65.9938	73.9449	1.12048
	u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621]	Squared		16120.1	20665.7	1.28198
278	40s ribosomal protein s11. [swissprot;acc:p04643]	Ranked		241.399	267.088	1.10642
	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	Ranked	0	11644	10763.4	1.08181
	bystin. [swissprot;acc:q13895]	Squared		26569.7	32857.7	1.23666
	cylindromatosis (turban tumor syndrome); cylindromatosis 1, turban tumor syndrome. [refseq;acc:nm_015247]	Rooted		34.0153	31.1803	1.09092
	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]	Squared	1	16120.1	20665.7	1.28198
	ribosomal protein s6 kinase-like 1. [refseq;acc:nm_031464]	Rooted	1	65.9938	73.9449	1.12048
	rna-binding protein nova-1 (neuro-oncological ventral antigen 1) (onconeural ventral antigen-1) (paraneoplastic ri antigen) (ventral neuron-specific protein 1). [swissprot;acc:p51513]	Measured	0	2162.33	1932	1.11922
	transcription factor lbx1. [swissprot;acc:p52954]	Measured	1	3119.98	2579.49	1.20953
279	anaphase promoting complex subunit 11 (hepatocellular carcinoma associated ring finger protein) (hspc214). [swissprot;acc:q9nyg5]	Ranked	0	10614.2	9812.39	1.08171
	cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [refseq;acc:nm_006614]	Measured		545.902	610.424	1.11819
	dipeptidyl aminopeptidase-like protein 6 (dipeptidylpeptidase vi) (dipeptidylpeptidase 6) (dipeptidyl peptidase iv like protein) (dipeptidyl aminopeptidase-related protein) (dppx). [swissprot;acc:p42658]	Rooted		33.1655	30.4161	1.09039
	dj947l8.1.1 (novel cub and sushi (scr repeat) domain protein) (fragment). [sptrembl;acc:q9h4v7]	Squared		229.508	283.721	1.23621
	histone acetyltransferase type b subunit 2 (retinoblastoma binding protein p46) (retinoblastoma-binding protein 7) (rbbp-7). [swissprot;acc:q16576]	Ranked	1	252.644	228.42	1.10605
	mosaic protein lgn. [swissprot;acc:p81274]	Measured		3119.98	2579.49	1.20953
	musashi 2 isoform a. [refseq;acc:nm_138962]	Squared		15569.5	19953.6	1.28158

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/