MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Gene	red	green	Value Type	Rank	Interaction Map	description	Filtered	network_comparison

Results: HTML CSV LaTeX

Showing element 558 to 607 of 3228 in total

Network Comparison Type  : Divided
Value Type  : Measured
Interaction Map  : High confidence
Filtered  : 1

red	green	Rank	description	network_comparison
3119.98	2579.49	276	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]	1.20953
		277	regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081]
		278	transcription factor lbx1. [swissprot;acc:p52954]
		279	mosaic protein lgn. [swissprot;acc:p81274]
		280	regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6]
		281	guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471]
		282	rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736]
3153.1	3762.56	317	adiponectin receptor 2. [refseq;acc:nm_024551]	1.19329
3199.4	3870.8	273	eukaryotic translation initiation factor 5 (eif-5). [swissprot;acc:p55010]	1.20985
3349.9	4362.61	144	sad1/unc-84 protein-like 1. [swissprot;acc:o94901]	1.30231
3370.46	3444.18	2547	3-phosphoinositide dependent protein kinase-1 (ec 2.7.1.37) (hpdk1). [swissprot;acc:o15530]	1.02187
3377.01	3411.47	2641	dna-repair protein complementing xp-g cells (xeroderma pigmentosum group g complementing protein) (dna excision repair protein ercc-5). [swissprot;acc:p28715]	1.0102
3432.96	4081.21	326	atp-dependent rna helicase ddx24 (dead-box protein 24). [swissprot;acc:q9gzr7]	1.18883
3436.65	3531.96	2491	hepatocyte nuclear factor 4-gamma (hnf-4-gamma). [swissprot;acc:q14541]	1.02773
		2492	growth arrest and dna-damage-inducible protein gadd45 gamma (cytokine responsive protein cr6). [swissprot;acc:o95257]
		2493	growth arrest and dna-damage-inducible protein gadd45 alpha (dna- damage inducible transcript 1) (ddit1). [swissprot;acc:p24522]
		2494	hepatocyte nuclear factor 4-alpha (hnf-4-alpha) (transcription factor hnf-4) (transcription factor 14). [swissprot;acc:p41235]
		2495	growth arrest and dna-damage-inducible protein gadd45 beta (negative growth-regulatory protein myd118) (myeloid differentiation primary response protein myd118). [swissprot;acc:o75293]
3494.31	4129.6	335	probable atp-dependent 61 kda nucleolar rna helicase (dead-box protein 21). [swissprot;acc:q9ny93]	1.18181
3496.21	3652.28	2321	dna polymerase epsilon p17 subunit (dna polymerase epsilon subunit 3) (chromatin accessibility complex 17) (huchrac17) (chrac-17). [swissprot;acc:q9nrf9]	1.04464
3544.03	3359.43	2099	methionine aminopeptidase 1 (ec 3.4.11.18) (metap 1) (map 1) (peptidase m 1). [swissprot;acc:p53582]	1.05495
		2100	methionine aminopeptidase 2 (ec 3.4.11.18) (metap 2) (peptidase m 2) (initiation factor 2 associated 67 kda glycoprotein) (p67) (p67eif2). [swissprot;acc:p50579]
3559.49	3360.39	1988	protein translation factor sui1 homolog gc20. [swissprot;acc:o60739]	1.05925
3560.24	3364.84	2023	protein translation factor sui1 homolog (sui1iso1). [swissprot;acc:p41567]	1.05807
3560.63	3381.34	2152	40s ribosomal protein s23. [swissprot;acc:p39028]	1.05302
		2153	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]
3568.18	3675.65	2485	zinc finger protein 174 (aw-1). [swissprot;acc:q15697]	1.03012
3568.45	3675.97	2484	zinc finger imprinted 2. [swissprot;acc:q9nzv7]	1.03013
3568.8	3676.38	2483	zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022]	1.03014
	3676.39	2481	zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58]	1.03015
3568.84	3676.43	2477	zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028]
3568.95	3676.56	2480	zinc finger protein 305. [swissprot;acc:o43309]
3568.96	3676.57	2478	zinc finger protein 232. [swissprot;acc:q9uny5]
3568.99	3676.6	2479	zinc finger protein 99. [refseq;acc:nm_032164]
	3676.61	2482	zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771]
3569.06	3392.22	2163	dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [swissprot;acc:p24928]	1.05213
3569.07	3676.7	2476	zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6]	1.03016
3573.66	3682.14	2475	zinc finger protein 444; endothelial zinc finger protein 2. [refseq;acc:nm_018337]	1.03036
3582.57	3357.6	1756	40s ribosomal protein s29. [swissprot;acc:p30054]	1.067
3583.56	4194.95	369	ccaat-box-binding transcription factor (ccaat-binding factor) (cbf). [swissprot;acc:q03701]	1.17061
3586.3	3414.4	2186	60s ribosomal protein l12 like protein. [sptrembl;acc:o60886]	1.05035
3586.31	3414.41	2187	dj999l4.1 (novel protein similar to ribosomal protein l12 (rpl12)). [sptrembl;acc:q9nq02]
3586.32	3414.42	2185	60s ribosomal protein l12. [swissprot;acc:p30050]
3590.56	3422.6	2211	40s ribosomal protein s20. [swissprot;acc:p17075]	1.04907
3591.95	3375.34	1840	cholinephosphate cytidylyltransferase a (ec 2.7.7.15) (phosphorylcholine transferase a) (ctp:phosphocholine cytidylyltransferase a) (ct a) (cct a) (cct-alpha). [swissprot;acc:p49585]	1.06417
		1841	fad synthetase. [refseq;acc:nm_025207]
		1842	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2 (paps synthethase 2) (papss 2) (sulfurylase kinase 2) (sk2) (sk 2) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o95340]
		1843	ligatin (hepatocellular carcinoma-associated antigen 56). [swissprot;acc:p41214]
		1844	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 1 (paps synthethase 1) (papss 1) (sulfurylase kinase 1) (sk1) (sk 1) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [swissprot;acc:o43252]
		1845	nadph-cytochrome p450 reductase (ec 1.6.2.4) (cpr) (p450r). [swissprot;acc:p16435]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.