Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 2151 to 2200 of 3730 in total 
Value Type	Ranked
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	green	red	network_comparison	
1649	neurotrypsin precursor (ec 3.4.21.-) (motopsin) (leydin). [source:swissprot;acc:p56730]	215.942	219.062	1.01445	
1650	ring finger protein 44. [source:refseq;acc:nm_014901]	215.942	219.062	1.01445	
1651	phosphatidylinositol 3-kinase regulatory alpha subunit (pi3-kinase p85-alpha subunit) (ptdins-3-kinase p85-alpha) (pi3k). [source:swissprot;acc:p27986]	215.942	219.062	1.01445	
1652	ring finger protein 38. [source:refseq;acc:nm_022781]	215.942	219.062	1.01445	
1653	phosphatidylinositol 3-kinase regulatory gamma subunit (pi3-kinase p85-gamma subunit) (ptdins-3-kinase p85-gamma) (p55pik). [source:swissprot;acc:q92569]	215.942	219.062	1.01445	
1654	sterol regulatory element binding protein cleavage-activating protein (srebp cleavage-activating protein) (scap). [source:swissprot;acc:q12770]	215.942	219.062	1.01445	
1655	atp synthase beta chain, mitochondrial precursor (ec 3.6.3.14). [source:swissprot;acc:p06576]	215.942	219.062	1.01445	
1656	phosphatidylinositol 3-kinase regulatory beta subunit (pi3-kinase p85-beta subunit) (ptdins-3-kinase p85-beta). [source:swissprot;acc:o00459]	215.942	219.062	1.01445	
1657	cleavage and polyadenylation specific factor 5, 25 kd subunit; pre-mrna cleavage factor im (25kd); pre-mrna cleavage factor im, 25kd subunit. [source:refseq;acc:nm_007006]	216.195	219.314	1.01443	
1658	atp synthase alpha chain, mitochondrial precursor (ec 3.6.3.14). [source:swissprot;acc:p25705]	214.826	217.925	1.01443	
1659	28s ribosomal protein s18a, mitochondrial precursor (mrp-s18-a) (mrps18a) (mrp-s18-3). [source:swissprot;acc:q9nvs2]	214.826	217.925	1.01443	
1660	early endosome antigen 1, 162kd; early endosome-associated protein. [source:refseq;acc:nm_003566]	231.933	228.654	1.01434	
1661	adenylosuccinate synthase-like 1. [source:refseq;acc:nm_152328]	201.551	204.437	1.01432	
1662	transcription factor-like protein mrgx (morf-related gene x protein) (mortality factor 4-like 2) (msl3-2 protein). [source:swissprot;acc:q15014]	231.747	228.477	1.01431	
1663	tryptophan 2,3-dioxygenase (ec 1.13.11.11) (tryptophan pyrrolase) (tryptophanase) (tryptophan oxygenase) (tryptamin 2,3-dioxygenase) (trpo). [source:swissprot;acc:p48775]	215.26	218.335	1.01429	
1664	transcription factor-like protein morf4 (mortality factor 4) (cellular senescence-related protein 1) (sen1). [source:swissprot;acc:q9y690]	231.74	228.484	1.01425	
1665	adenylosuccinate synthetase (ec 6.3.4.4) (imp--aspartate ligase) (adss) (ampsase). [source:swissprot;acc:p30520]	201.564	204.433	1.01423	
1666	karyopherin beta 2b, transportin; importin 3. [source:refseq;acc:nm_013433]	215.612	218.679	1.01422	
1667	cathepsin b precursor (ec 3.4.22.1) (cathepsin b1) (app secretase). [source:swissprot;acc:p07858]	211.898	214.898	1.01416	
1668	survival motor neuron protein (component of gems 1) (gemin1). [source:swissprot;acc:q16637]	231.729	228.496	1.01415	
1669	ras-related c3 botulinum toxin substrate 1 (p21-rac1) (ras-like protein tc25). [source:swissprot;acc:p15154]	231.729	228.496	1.01415	
1670	ras-related c3 botulinum toxin substrate 3 (p21-rac3). [source:swissprot;acc:o14658]	231.729	228.496	1.01415	
1671	nucleoporin 54kda; nucleoporin p54. [source:refseq;acc:nm_017426]	231.729	228.496	1.01415	
1672	ras-related c3 botulinum toxin substrate 2 (p21-rac2) (small g protein) (gx). [source:swissprot;acc:p15153]	231.729	228.496	1.01415	
1673	dna replication licensing factor mcm5 (cdc46 homolog) (p1-cdc46). [source:swissprot;acc:p33992]	231.729	228.496	1.01415	
1674	survival of motor neuron protein-interacting protein 1 (smn- interacting protein 1) (component of gems 2) (gemin2). [source:swissprot;acc:o14893]	231.729	228.496	1.01415	
1675	probable atp-dependent rna helicase ddx20 (dead-box protein 20) (dead- box protein dp 103) (component of gems 3) (gemin3). [source:swissprot;acc:q9uhi6]	231.729	228.496	1.01415	
1676	importin beta-2 subunit (karyopherin beta-2 subunit) (transportin) (m9 region interaction protein) (mip). [source:swissprot;acc:q92973]	215.645	218.691	1.01413	
1677	glutathione s-transferase p (ec 2.5.1.18) (gst class-pi) (gstp1-1). [source:swissprot;acc:p09211]	221.732	218.654	1.01408	
1678	serine/threonine protein kinase 23 (ec 2.7.1.37) (muscle-specific serine kinase 1) (mssk-1). [source:swissprot;acc:q9upe1]	213.889	216.899	1.01407	
1679	gtp binding protein 2. [source:refseq;acc:nm_019096]	213.889	216.899	1.01407	
1680	cyclic-amp-dependent transcription factor atf-6 beta (activating transcription factor 6 beta) (atf6-beta) (camp responsive element binding protein-like 1) (camp response element binding protein-related protein) (creb-rp) (g13 protein). [source:swissprot;acc:q99941]	213.889	216.899	1.01407	
1681	dna segment on chromosome 6(unique) 2654 expressed sequence; dna segment on chromosome x (unique) 2654 expressed sequence. [source:refseq;acc:nm_012135]	213.889	216.899	1.01407	
1682	sfrs protein kinase 2 isoform b. [source:refseq;acc:nm_182691]	213.889	216.899	1.01407	
1683	cyclic-amp-dependent transcription factor atf-6 alpha (activating transcription factor 6 alpha) (atf6-alpha). [source:swissprot;acc:p18850]	213.889	216.899	1.01407	
1684	sfrs protein kinase 1; sr protein kinase 1. [source:refseq;acc:nm_003137]	213.889	216.899	1.01407	
1685	xap-5 protein (hxc-26 protein). [source:swissprot;acc:q14320]	213.889	216.899	1.01407	
1686	putative sialoglycoprotease type 2. [source:refseq;acc:nm_022353]	217.704	220.75	1.01399	
1687	atp synthase delta chain, mitochondrial precursor (ec 3.6.3.14). [source:swissprot;acc:p30049]	212.386	215.345	1.01393	
1688	transcription factor-like protein mrg15 (morf-related gene 15 protein) (mortality factor 4-like 1) (msl3-1 protein) (hspc008/hspc061). [source:swissprot;acc:q9ubu8]	231.703	228.523	1.01392	
1689	dead-box protein 4 (vasa homolog). [source:swissprot;acc:q9nqi0]	225.163	228.277	1.01383	
1690	40s ribosomal protein s24 (s19). [source:swissprot;acc:p16632]	227.184	224.091	1.0138	
1691	translation initiation factor if-2. [source:swissprot;acc:o60841]	214.315	217.263	1.01376	
1692	rna-binding protein 9 (rna binding motif protein 9) (hexaribonucleotide binding protein 2) (repressor of tamoxifen transcriptional activity). [source:swissprot;acc:o43251]	215.551	218.515	1.01375	
1693	inosine-5'-monophosphate dehydrogenase 2 (ec 1.1.1.205) (imp dehydrogenase 2) (impdh-ii) (impd 2). [source:swissprot;acc:p12268]	215.971	218.937	1.01373	
1694	gmp synthase [glutamine-hydrolyzing] (ec 6.3.5.2) (glutamine amidotransferase) (gmp synthetase). [source:swissprot;acc:p49915]	215.971	218.937	1.01373	
1695	inosine-5'-monophosphate dehydrogenase 1 (ec 1.1.1.205) (imp dehydrogenase 1) (impdh-i) (impd 1). [source:swissprot;acc:p20839]	215.971	218.937	1.01373	
1696	polyadenylate-binding protein 3 (poly(a)-binding protein 3) (pabp 3) (testis-specific poly(a)-binding protein). [source:swissprot;acc:q9h361]	214.69	217.624	1.01367	
1697	hskin17 protein. [source:refseq;acc:nm_012311]	214.69	217.624	1.01367	
1698	carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [source:swissprot;acc:p43155]	214.69	217.624	1.01367	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/