Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 2130 to 2179 of 3228 in total 
Value Type	Measured
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	green	network_comparison	
2130	ba508n22.1 (hspc025) (fragment). [source:sptrembl;acc:q9hcw5]	5328.73	5616.59	1.05402	
2131	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [source:swissprot;acc:p50851]	5328.73	5616.59	1.05402	
2132	protein c20orf45 (cgi-107). [source:swissprot;acc:q9y3b1]	5328.73	5616.59	1.05402	
2133	eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [source:swissprot;acc:q9y262]	5328.73	5616.59	1.05402	
2134	putative rna-binding protein 7 (rna binding motif protein 7). [source:swissprot;acc:q9y580]	5328.73	5616.59	1.05402	
2135	exocyst complex component sec6. [source:swissprot;acc:o60645]	7387.42	7785.45	1.05388	
2136	60s ribosomal protein l19. [source:swissprot;acc:p14118]	3687.49	3499.2	1.05381	
2137	sh3 domain-binding glutamic acid-rich protein (sh3bgr protein) (21- glutamic acid-rich protein) (21-garp). [source:swissprot;acc:p55822]	5859.1	6173.7	1.05369	
2138	oxidation resistance 1. [source:refseq;acc:nm_181354]	5859.1	6173.7	1.05369	
2139	lats, large tumor suppressor, homolog 2; lats (large tumor suppressor, drosophila) homolog 2. [source:refseq;acc:nm_014572]	5859.1	6173.7	1.05369	
2140	dymeclin. [source:refseq;acc:nm_017653]	5859.1	6173.7	1.05369	
2141	sh3 domain-binding glutamic acid-rich-like protein. [source:swissprot;acc:o75368]	5859.1	6173.7	1.05369	
2142	lats homolog 1. [source:refseq;acc:nm_004690]	5859.1	6173.7	1.05369	
2143	sh3 domain-binding glutamic acid-rich-like protein 2 (fovea-associated sh3 domain binding protein). [source:swissprot;acc:q9ujc5]	5859.1	6173.7	1.05369	
2144	nuclear receptor coactivator 7; estrogen receptor associated protein 140 kda. [source:refseq;acc:nm_181782]	5859.1	6173.7	1.05369	
2145	dj132f21.2 (contains a novel protein similar to the l82e from drosophila) (fragment). [source:sptrembl;acc:q9h125]	5859.1	6173.7	1.05369	
2146	tbc1 domain family protein c22orf4-like (fragment). [source:swissprot;acc:q9nu19]	5859.1	6173.7	1.05369	
2147	tbc1 domain family protein c22orf4. [source:swissprot;acc:q8wua7]	5859.1	6173.7	1.05369	
2148	deoxycytidylate deaminase (ec 3.5.4.12) (dcmp deaminase). [source:swissprot;acc:p32321]	4644.58	4892.06	1.05328	
2149	importin beta-2 subunit (karyopherin beta-2 subunit) (transportin) (m9 region interaction protein) (mip). [source:swissprot;acc:q92973]	5778.62	6086.03	1.0532	
2150	karyopherin beta 2b, transportin; importin 3. [source:refseq;acc:nm_013433]	5779.82	6086.64	1.05308	
2151	early endosome antigen 1, 162kd; early endosome-associated protein. [source:refseq;acc:nm_003566]	4871.11	5129.63	1.05307	
2152	40s ribosomal protein s23. [source:swissprot;acc:p39028]	3560.63	3381.34	1.05302	
2153	28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [source:swissprot;acc:o15235]	3560.63	3381.34	1.05302	
2154	acyl-coenzyme a oxidase 2, peroxisomal (ec 1.3.3.6) (branched-chain acyl-coa oxidase) (brcacox) (trihydroxycoprostanoyl-coa oxidase) (thccox) (thca-coa oxidase). [source:swissprot;acc:q99424]	6884.69	7247.36	1.05268	
2155	centaurin gamma 2. [source:swissprot;acc:q9upq3]	5701.81	6000.03	1.0523	
2156	general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [source:swissprot;acc:o60763]	5701.81	6000.03	1.0523	
2157	centaurin gamma 1. [source:swissprot;acc:q99490]	5701.81	6000.03	1.0523	
2158	centaurin gamma 3. [source:swissprot;acc:q96p47]	5701.81	6000.03	1.0523	
2159	serine/threonine-protein kinase receptor r2 precursor (ec 2.7.1.37) (skr2) (activin receptor-like kinase 4) (alk-4) (actr-ib). [source:swissprot;acc:p36896]	5379.49	5660.18	1.05218	
2160	activin a receptor, type ic; activin receptor-like kinase 7. [source:refseq;acc:nm_145259]	5379.55	5660.25	1.05218	
2161	neuronal calcium sensor 1 (ncs-1) (frequenin homolog) (frequenin-like protein) (frequenin-like ubiquitous protein). [source:swissprot;acc:p36610]	5379.33	5660	1.05218	
2162	tgf-beta receptor type i precursor (ec 2.7.1.37) (tgfr-1) (tgf-beta type i receptor) (serine/threonine-protein kinase receptor r4) (skr4) (activin receptor-like kinase 5) (alk-5). [source:swissprot;acc:p36897]	5379.03	5659.64	1.05217	
2163	dna-directed rna polymerase ii largest subunit (ec 2.7.7.6) (rpb1). [source:swissprot;acc:p24928]	3569.06	3392.22	1.05213	
2164	ubiquinone biosynthesis monooxgenase coq6 (ec 1.14.13.-) (cgi-10). [source:swissprot;acc:q9y2z9]	6952.66	7315.06	1.05212	
2165	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase). [source:refseq;acc:nm_003679]	6952.66	7315.06	1.05212	
2166	squalene monooxygenase (ec 1.14.99.7) (squalene epoxidase) (se). [source:swissprot;acc:q14534]	6952.66	7315.06	1.05212	
2167	mitochondrial 60s ribosomal protein l3 (l3mt). [source:swissprot;acc:p09001]	3641.62	3461.4	1.05207	
2168	hydroxyacid oxidase 1 (ec 1.1.3.15) (haox1) (glycolate oxidase) (gox). [source:swissprot;acc:q9ujm8]	4561.75	4799.24	1.05206	
2169	60s ribosomal protein l5. [source:swissprot;acc:p46777]	3639.65	3459.64	1.05203	
2170	exonuclease 1 isoform b; rad2 nuclease family member, homolog of s. cerevisiae exonuclease 1. [source:refseq;acc:nm_006027]	5825.61	6126.74	1.05169	
2171	phd finger protein 9. [source:refseq;acc:nm_018062]	5825.61	6126.74	1.05169	
2172	small optic lobes homolog; small optic lobes, drosophila, homolog of. [source:refseq;acc:nm_005632]	5825.61	6126.74	1.05169	
2173	epithelial-cadherin precursor (e-cadherin) (uvomorulin) (cadherin-1) (cam 120/80). [source:swissprot;acc:p12830]	3641.4	3462.96	1.05153	
2174	c367g8.3 (novel protein similar to rpl23a (60s ribosomal protein l23a)) (60s ribosomal protein l23a like). [source:sptrembl;acc:q9br02]	3641.45	3463.02	1.05152	
2175	60s ribosomal protein l23a. [source:swissprot;acc:p29316]	3642.13	3463.88	1.05146	
2176	potassium voltage-gated channel subfamily a member 2 (potassium channel kv1.2) (rbk2) (hbk5) (ngk1) (mk2) (hukiv). [source:swissprot;acc:p16389]	6674.58	7015.93	1.05114	
2177	elav-like protein 3 (hu-antigen c) (huc) (paraneoplastic cerebellar degeneration-associated antigen) (paraneoplastic limbic encephalitis antigen 21). [source:swissprot;acc:q14576]	5887.43	6187.82	1.05102	
2178	elav-like protein 1 (hu-antigen r) (hur). [source:swissprot;acc:q15717]	5893.23	6193.33	1.05092	
2179	elav-like protein 4 (paraneoplastic encephalomyelitis antigen hud) (hu-antigen d). [source:swissprot;acc:p26378]	5896.51	6196.59	1.05089	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/