Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene Hugo description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 2108 to 2157 of 8289 in total
Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1
Rank
Hugo
description
Interaction Map
red
green
network_comparison
1054 RUNX2 runt-related transcription factor 2 (core-binding factor, alpha 1 subunit) (cbf-alpha 1) (acute myeloid leukemia 3 protein) (oncogene aml-3) (polyomavirus enhancer binding protein 2 alpha a subunit) (pebp2-alpha a) (pea2-alpha a) (sl3-3 enhancer factor 1 alpha a subunit) (sl3/akv core-binding factor alpha a subunit) (osteoblast- specific transcription factor 2) (osf-2). [swissprot;acc:q13950] Low confidence 210.793 205.841 1.02406
1055 ASNSD1 hcv ns3-transactivated protein 1. [refseq;acc:nm_019048] High confidence 219.01 212.468 1.03079
NME3 nucleoside diphosphate kinase 3 (ec 2.7.4.6) (ndk 3) (ndp kinase 3) (nm23-h3) (dr-nm23). [swissprot;acc:q13232] Low confidence 199.656 194.966 1.02406
1056 ATP6V1A vacuolar atp synthase catalytic subunit a, ubiquitous isoform (ec 3.6.3.14) (v-atpase a subunit 1) (vacuolar proton pump alpha subunit 1) (v-atpase 69 kda subunit 1) (isoform va68). [swissprot;acc:p38606] High confidence 219.01 212.468 1.03079
FARS2 phenylalanine-trna synthetase. [refseq;acc:nm_006567] Low confidence 202.569 197.815 1.02403
1057 ASNS asparagine synthetase [glutamine-hydrolyzing] (ec 6.3.5.4) (glutamine- dependent asparagine synthetase) (ts11 cell cycle control protein). [swissprot;acc:p08243] High confidence 219.01 212.468 1.03079
FARSB phenylalanyl-trna synthetase beta chain (ec 6.1.1.20) (phenylalanine-- trna ligase beta chain) (phers) (hspc173). [swissprot;acc:q9nsd9] Low confidence 202.569 197.815 1.02403
1058 ATXN2L ataxin 2 related protein isoform a; ataxin-2 domain protein. [refseq;acc:nm_007245] High confidence 228.105 221.293 1.03078
TRAPPC1 bet5 homolog (multiple myeloma protein 2) (mum-2). [swissprot;acc:q9y5r8] Low confidence 198.804 194.142 1.02401
1059 no value ataxin 2; olivopontocerebellar ataxia 2, autosomal dominant. [refseq;acc:nm_002973] High confidence 228.105 221.293 1.03078
SLC7A4 cationic amino acid transporter-4 (cat-4) (cat4). [swissprot;acc:o43246] Low confidence 200.552 195.852 1.024
1060 NLK nemo-like kinase; likely ortholog of mouse nemo like kinase. [refseq;acc:nm_016231] High confidence 218.162 211.648 1.03078
SYT12 synaptotagmin xii (sytxii). [swissprot;acc:q8iv01] Low confidence 203.527 198.76 1.02398
1061 ERC1 elks protein. [refseq;acc:nm_015064] High confidence 218.162 211.648 1.03078
YBX2 germ cell specific y-box binding protein; contrin. [refseq;acc:nm_015982] Low confidence 204.104 199.324 1.02398
1062 no value dna-crosslink repair gene snm1. [refseq;acc:nm_014881] 203.048 198.295 1.02397
ZNF174 zinc finger protein 174 (aw-1). [swissprot;acc:q15697] High confidence 269.963 278.239 1.03066
1063 no value t-cell activation protein phosphatase 2c. [refseq;acc:nm_139283] Low confidence 203.048 198.295 1.02397
zinc finger imprinted 2. [swissprot;acc:q9nzv7] High confidence 269.96 278.232 1.03064
1064 COQ7 ubiquinone biosynthesis protein coq7 homolog (coenzyme q biosynthesis protein 7 homolog) (timing protein clk-1 homolog). [swissprot;acc:q99807] Low confidence 201.995 197.269 1.02396
ZNF24 zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028] High confidence 269.955 278.221 1.03062
1065 ABCF2 atp-binding cassette, sub-family f, member 2 (iron inhibited abc transporter 2) (hussy-18). [swissprot;acc:q9ug63] Low confidence 201.115 196.411 1.02395
ZSCAN12 zinc finger protein 305. [swissprot;acc:o43309] High confidence 269.954 278.219 1.03062
1066 YPEL2 yippee-like protein 2 (digeorge syndrome-related protein fksg4). [swissprot;acc:q96qa6] Low confidence 187.762 183.372 1.02394
ZNF18 zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022] High confidence 269.956 278.223 1.03062
1067 YPEL4 yippee-like protein 5. [swissprot;acc:q96ns1] Low confidence 187.77 183.38 1.02394
ZNF215 zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58] High confidence 269.956 278.223 1.03062
1068 UTP3 disrupter of silencing 10. [refseq;acc:nm_020368] Low confidence 199.958 195.283 1.02394
ZNF274 zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6] High confidence 269.953 278.215 1.03061
1069 YPEL3 yippee-like protein 3 (digeorge syndrome-related protein fksg5). [swissprot;acc:q9bsj4] Low confidence 187.761 183.371 1.02394
ZNF232 zinc finger protein 232. [swissprot;acc:q9uny5] High confidence 269.954 278.218 1.03061
1070 SH3GL2 sh3-containing grb2-like protein 2 (sh3 domain protein 2a) (endophilin 1) (een-b1). [swissprot;acc:q99962] Low confidence 203.828 199.067 1.02392
ZNF394 zinc finger protein 99. [refseq;acc:nm_032164] High confidence 269.954 278.218 1.03061
1071 no value dna-directed rna polymerase i 16 kda polypeptide (ec 2.7.7.6) (rpa16). [swissprot;acc:q9y2s0] 231.277 238.356
TRIT1 trna isopentenylpyrophosphate transferase. [refseq;acc:nm_017646] Low confidence 200.19 195.515 1.02391
1072 RWDD1 rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952] 203.286 198.543 1.02389
ZNF213 zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771] High confidence 269.954 278.217 1.03061
1073 HNRPUL1 e1b-55kda-associated protein 5 isoform a. [refseq;acc:nm_007040] Low confidence 210.723 205.809 1.02388
WBP2 ww domain binding protein 2 (wbp-2). [swissprot;acc:q969t9] High confidence 216.901 210.485 1.03048
1074 COPB2 coatomer beta' subunit (beta'-coat protein) (beta'-cop) (p102). [swissprot;acc:p35606] 174.387 179.697 1.03045
FDX1 adrenodoxin, mitochondrial precursor (adrenal ferredoxin) (hepatoredoxin) (ferredoxin 1). [swissprot;acc:p10109] Low confidence 191.57 187.103 1.02387
1075 no value adenosine deaminase (ec 3.5.4.4) (adenosine aminohydrolase). [swissprot;acc:p00813] 202.317 197.601
COPG coatomer gamma subunit (gamma-coat protein) (gamma-cop). [swissprot;acc:q9y678] High confidence 174.387 179.697 1.03045
1076 COPZ1 coatomer zeta-1 subunit (zeta-1 coat protein) (zeta-1 cop) (cgi-120) (hspc181). [swissprot;acc:q9y3c3]
SGCZ sarcoglycan zeta; zeta-sarcoglycan. [refseq;acc:nm_139167] Low confidence 206.757 201.939 1.02386
1077 ARCN1 coatomer delta subunit (delta-coat protein) (delta-cop) (archain). [swissprot;acc:p48444] High confidence 174.387 179.697 1.03045
FZD5 frizzled 5 precursor (frizzled-5) (fz-5) (hfz5) (fze5). [swissprot;acc:q13467] Low confidence 206.587 201.773 1.02386
1078 KDELR2 er lumen protein retaining receptor 2 (kdel receptor 2) (elp-1). [swissprot;acc:p33947] 202.92 198.191
PPIE peptidyl-prolyl cis-trans isomerase e (ec 5.2.1.8) (ppiase e) (rotamase e) (cyclophilin e) (cyclophilin 33). [swissprot;acc:q9unp9] High confidence 174.387 179.697 1.03045
1079 COPZ2 coatomer zeta-2 subunit (zeta-2 coat protein) (zeta-2 cop). [swissprot;acc:q9p299]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/