Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type Interaction Map Gene Rank green Filtered description Network Comparison Type network_comparison red
Results: HTML CSV LaTeX Showing element 2075 to 2124 of 3228 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Network Comparison Type  : Divided
Rank
green
description
network_comparison
red
2075 223.483 cd109; gov system alloantigens on platelets. [refseq;acc:nm_133493] 1.00803 221.703
2076 peptidyl-prolyl cis-trans isomerase nima-interacting 1 (ec 5.2.1.8) (rotamase pin1) (ppiase pin1). [swissprot;acc:q13526]
2077 iroquois-class homeodomain protein irx-4 (iroquois homeobox protein 4). [swissprot;acc:p78413]
2078 213.814 fidgetin-like 1. [refseq;acc:nm_022116] 1.00794 215.511
2079 214.28 phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing gamma polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-gamma) (ptdins-3-kinase c2 gamma) (pi3k-c2gamma). [swissprot;acc:o75747] 1.00787 215.967
2080 phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]
2081 dynamin 1-like protein isoform 3; dynamin-like protein. [refseq;acc:nm_005690]
2082 phosphoinositide-3-kinase, class 2, alpha polypeptide; c2-containing phosphatidylinositol kinase. [refseq;acc:nm_002645]
2083 213.579 vacuolar protein sorting 16 (hvps16). [swissprot;acc:q9h269] 1.00786 215.258
2084 224.293 glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (ec 2.6.1.16) (hexosephosphate aminotransferase 1) (d-fructose-6- phosphate amidotransferase 1) (gfat 1) (gfat1). [swissprot;acc:q06210] 1.00784 222.548
2085 224.32 isocitrate dehydrogenase [nad] subunit alpha, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:p50213] 1.00782 222.58
2086 isocitrate dehydrogenase [nad] subunit beta, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:o43837]
2087 isocitrate dehydrogenase [nad] subunit gamma, mitochondrial precursor (ec 1.1.1.41) (isocitric dehydrogenase) (nad+-specific icdh). [swissprot;acc:p51553]
2088 216.433 maguk p55 subfamily member 3 (mpp3 protein) (discs, large homolog 3). [swissprot;acc:q13368] 1.00781 218.124
2089 213.479 serologically defined colon cancer antigen 16. [refseq;acc:nm_006649] 1.0078 215.144
2090 224.344 glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (ec 2.6.1.16) (hexosephosphate aminotransferase 2) (d-fructose-6- phosphate amidotransferase 2) (gfat 2) (gfat2). [swissprot;acc:o94808] 1.00779 222.609
2091 210.052 rna, u transporter 1; snurportin-1. [refseq;acc:nm_005701] 1.00775 211.679
2092 210.369 evolutionarily conserved signaling intermediate in toll pathway; ecsit. [refseq;acc:nm_016581] 1.00772 211.992
2093 208.387 ribokinase (ec 2.7.1.15). [swissprot;acc:q9h477] 1.00771 209.994
2094 205.747 pms1 protein homolog 2 (dna mismatch repair protein pms2). [swissprot;acc:p54278] 1.00765 207.321
2095 227.53 polymerase (dna directed) sigma; topoisomerase-related function protein 4-1; polymerase (dna-directed) sigma. [refseq;acc:nm_006999] 1.00763 229.266
2096 216.089 limkain beta 2. [refseq;acc:nm_025140] 1.00756 217.723
2097 213.39 delta-interacting protein a (hepatitis delta antigen interacting protein a). [swissprot;acc:q15834] 1.00745 214.979
2098 178.831 ret finger protein 2 (leukemia associated protein 5) (b-cell chronic lymphocytic leukemia tumor suppressor leu5) (putative tumor suppressor rfp2) (tripartite motif protein 13). [swissprot;acc:o60858] 1.00741 177.515
2099 213.27 ubiquitin-like protein smt3a. [swissprot;acc:p55854] 1.00737 211.71
2100 ubiquitin-like protein smt3b (sentrin 2) (hsmt3). [swissprot;acc:p55855]
2101 acrc protein; putative nuclear protein. [refseq;acc:nm_052957]
2102 210.263 eukaryotic translation initiation factor 5a (eif-5a) (eif-4d) (rev- binding factor). [swissprot;acc:p10159] 1.00736 208.727
2103 216.236 transketolase (ec 2.2.1.1) (tk). [swissprot;acc:p29401] 1.00731 214.666
2104 207.813 thymidylate kinase (ec 2.7.4.9) (dtmp kinase). [swissprot;acc:p23919] 1.00729 209.328
2105 210.111 eif-5a2 protein. [refseq;acc:nm_020390] 208.591
2106 196.061 insulin gene enhancer protein isl-1 (islet-1). [swissprot;acc:p20663] 1.00728 197.489
2107 217.801 lim domain only 7; zinc-finger domain-containing protein; lomp protein; f-box only protein 20; f-box protein fbx20. [refseq;acc:nm_005358] 1.00727 216.23
2108 217.93 argininosuccinate lyase (ec 4.3.2.1) (arginosuccinase) (asal). [swissprot;acc:p04424] 1.00726 216.36
2109 217.47 ran-binding protein 2 (ranbp2) (nuclear pore complex protein nup358) (nucleoporin nup358) (358 kda nucleoporin) (p270). [swissprot;acc:p49792] 1.00718 219.032
2110 209.607 conserved oligomeric golgi complex component 6. [swissprot;acc:q9y2v7] 1.00712 211.099
2111 217.511 ran-binding protein 2-like 1 isoform 2; sperm membrane protein bs-63; ran-binding protein 2-like 1. [refseq;acc:nm_032260] 1.00706 219.047
2112 224.989 dna-directed rna polymerases iii 12.5 kda polypeptide (ec 2.7.7.6) (rna polymerase iii c11 subunit) (hsc11p) (hrpc11) (my010 protein). [swissprot;acc:q9y2y1] 1.00705 223.415
2113 217.533 ran-binding protein 2-like 1 isoform 2; sperm membrane protein bs-63; ran-binding protein 2-like 1. [refseq;acc:nm_032260] 1.007 219.055
2114 213.14 triacylglycerol lipase, gastric precursor (ec 3.1.1.3) (gastric lipase) (gl). [swissprot;acc:p07098] 214.632
2115 ba304i5.1 (novel lipase) (fragment). [sptrembl;acc:q96lg2]
2116 lysosomal acid lipase/cholesteryl ester hydrolase precursor (ec 3.1.1.13) (lal) (acid cholesteryl ester hydrolase) (sterol esterase) (lipase a) (cholesteryl esterase). [swissprot;acc:p38571]
2117 seryl-trna synthetase, mitochondrial precursor (ec 6.1.1.11) (serine--trna ligase) (serrsmt). [swissprot;acc:q9np81]
2118 seryl-trna synthetase (ec 6.1.1.11) (serine--trna ligase) (serrs). [swissprot;acc:p49591]
2119 222.788 potassium channel modulatory factor 1; potassium channel modulatory factor; differentially expressed in branching tubulogenesis 91; zinc finger, zz domain containing 1. [refseq;acc:nm_020122] 1.00696 221.248
2120 solute carrier family 23, member 1 (sodium-dependent vitamin c transporter 1) (hsvct1) (na(+)/l-ascorbic acid transporter 1) (yolk sac permease-like molecule 3). [swissprot;acc:q9uhi7]
2121 heterogeneous nuclear ribonucleoprotein a3 (hnrnp a3) (d10s102). [swissprot;acc:p51991]
2122 207.911 galectin-9 (hom-hd-21) (ecalectin). [swissprot;acc:o00182] 206.473
2123 222.788 adp-ribosylation factor 4. [swissprot;acc:p18085] 221.248
2124 fused toes homolog; likely ortholog of mouse fused toes. [refseq;acc:nm_022476]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/