Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1975 to 2024 of 33156 in total
Network Comparison Type  : Divided
Filtered  : 1
Rank
description
Value Type
Interaction Map
red
green
network_comparison
247 solute carrier family 2, facilitated glucose transporter, member 8 (glucose transporter type 8) (glucose transporter type x1). [swissprot;acc:q9ny64] Squared Low confidence 51235.5 46861.2 1.09335
wiskott-aldrich syndrome protein (wasp). [swissprot;acc:p42768] Measured High confidence 6416.68 7865.15 1.22574
248 apobec-1 complementation factor isoform 1; apobec-1 stimulating protein; apo-b rna editing protein. [refseq;acc:nm_014576] Ranked 237.302 212.41 1.11719
jagged 1 precursor (jagged1) (hj1). [swissprot;acc:p78504] Rooted Low confidence 66.0195 69.7877 1.05708
myosin xv (unconventional myosin-15). [swissprot;acc:q9ukn7] Squared High confidence 8875.01 6768.05 1.31131
programmed cell death 4 isoform 1; programmed cell death 4; nuclear antigen h731. [refseq;acc:nm_014456] Low confidence 50352.9 46063.3 1.09312
proto-oncogene c-crk (p38) (adapter molecule crk). [swissprot;acc:p46108] Measured High confidence 6417.18 7859.6 1.22477
rabaptin, rab gtpase binding effector protein 1; rabaptin-5; neurocrescin. [refseq;acc:nm_004703] Low confidence 7615.71 8095.68 1.06302
retinal short-chain dehydrogenase/reductase 3. [refseq;acc:nm_016246] Ranked 162.755 155.476 1.04682
u6 snrna-associated sm-like protein lsm5. [swissprot;acc:q9y4y9] Rooted High confidence 56.0466 63.4808 1.13264
249 apg3p; pc3-96 protein. [refseq;acc:nm_022488] Measured Low confidence 10547.4 9924.56 1.06276
dual oxidase 1 precursor; nadph thyroid oxidase 1; flavoprotein nadph oxidase; nicotinamide adenine dinucleotide phosphate oxidase. [refseq;acc:nm_017434] Ranked 210.487 201.076 1.0468
glycogen phosphorylase, muscle form (ec 2.4.1.1) (myophosphorylase). [swissprot;acc:p11217] Squared High confidence 8875.01 6768.05 1.31131
myocyte-specific enhancer factor 2c. [swissprot;acc:q06413] Rooted Low confidence 66.0195 69.7877 1.05708
ns1-associated protein 1. [refseq;acc:nm_006372] Ranked High confidence 237.302 212.41 1.11719
ral guanine nucleotide dissociation stimulator-like 1 (ralgds-like 1). [swissprot;acc:q9nzl6] Squared Low confidence 49409.1 45229.3 1.09241
transcription factor iiib 90 kda subunit (tfiiib90) (htfiiib90) (b- related factor 1) (hbrf) (tata box-binding protein-associated factor, rna polymerase iii, subunit 2) (taf3b2). [swissprot;acc:q92994] Rooted High confidence 55.5965 62.9349 1.13199
tyrosine-protein kinase abl2 (ec 2.7.1.112) (tyrosine kinase arg). [swissprot;acc:p42684] Measured 6417.18 7859.59 1.22477
250 c-terminal binding protein 2 (ctbp2). [swissprot;acc:p56545] Squared 69201.8 53013.4 1.30536
diacylglycerol o-acyltransferase 1 (ec 2.3.1.20) (diglyceride acyltransferase) (acat related gene product 1). [swissprot;acc:o75907] Ranked Low confidence 210.443 201.051 1.04671
heterogeneous nuclear ribonucleoprotein r (hnrnp r). [swissprot;acc:o43390] High confidence 237.302 212.41 1.11719
large neutral amino acids transporter small subunit 2 (l-type amino acid transporter 2) (hlat2). [swissprot;acc:q9uhi5] Measured Low confidence 6975.98 7412.76 1.06261
myocyte-specific enhancer factor 2a (serum response factor-like protein 1). [swissprot;acc:q02078] Rooted 66.0188 69.7871 1.05708
nucleolar protein family a, member 1; gar1 protein. [refseq;acc:nm_018983] High confidence 55.5965 62.9349 1.13199
proto-oncogene tyrosine-protein kinase src (ec 2.7.1.112) (p60-src) (c-src). [swissprot;acc:p12931] Measured 6417.18 7859.6 1.22477
rab11-family interacting protein 4. [refseq;acc:nm_032932] Squared Low confidence 34469.6 37645.4 1.09213
251 b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844] High confidence 69165.6 52992.1 1.30521
eferin. [swissprot;acc:o75154] Low confidence 34469.6 37645.4 1.09213
kynureninase (ec 3.7.1.3) (l-kynurenine hydrolase). [swissprot;acc:q16719] Measured 8527.55 9058.09 1.06221
max protein. [swissprot;acc:p25912] Rooted High confidence 56.3054 63.7148 1.13159
nadph oxidase, ef hand calcium-binding domain 5. [refseq;acc:nm_024505] Ranked Low confidence 210.415 201.035 1.04666
oligopeptide transporter, small intestine isoform (peptide transporter 1) (intestinal h+/peptide cotransporter) (solute carrier family 15, member 1). [swissprot;acc:p46059] High confidence 186.172 166.661 1.11707
septin 7 (cdc10 protein homolog). [swissprot;acc:q16181] Rooted Low confidence 90.452 95.6145 1.05707
tyrosine-protein kinase hck (ec 2.7.1.112) (p59-hck/p60-hck) (hemopoietic cell kinase). [swissprot;acc:p08631] Measured High confidence 6417.18 7859.6 1.22477
252 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7] Low confidence 8492.92 9018.94 1.06194
crk-like protein. [swissprot;acc:p46109] High confidence 6417.18 7859.6 1.22477
cytochrome b-245 heavy chain (p22 phagocyte b-cytochrome) (neutrophil cytochrome b, 91 kda polypeptide) (cgd91-phox) (gp91-phox) (heme binding membrane glycoprotein gp91phox) (cytochrome b(558) beta chain) (superoxide-generating nadph oxidase heavy chain subunit). [swissprot;acc:p04839] Ranked Low confidence 210.414 201.035 1.04665
eukaryotic translation initiation factor 4 gamma (eif-4-gamma) (eif- 4g) (eif4g) (p220). [swissprot;acc:q04637] High confidence 237.292 212.457 1.11689
nuclear transcription factor y subunit beta (nf-y protein chain b) (nf-yb) (ccaat-binding transcription factor subunit a) (cbf-a) (caat- box dna binding protein subunit b). [swissprot;acc:p25208] Rooted 51.6736 58.4422 1.13099
pas domain containing serine/threonine kinase; pas-serine/threonine kinase. [refseq;acc:nm_015148] Squared 69165 52991.7 1.3052
ras-related gtp binding a; ras-related gtp-binding protein. [refseq;acc:nm_006570] Rooted Low confidence 86.7994 91.752 1.05706
ras-related protein r-ras (p23). [swissprot;acc:p10301] Squared 50409.8 46187.4 1.09142
253 b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [swissprot;acc:p41182] High confidence 69165 52991.7 1.3052
calcium-transporting atpase type 2c, member 1 (ec 3.6.3.8) (atpase 2c1) (atp-dependent ca(2+) pump pmr1) (hussy-28). [swissprot;acc:p98194] Rooted Low confidence 66.0401 69.8058 1.05702
fructose-1,6-bisphosphatase isozyme 2 (ec 3.1.3.11) (d-fructose-1,6- bisphosphate 1-phosphohydrolase) (fbpase). [swissprot;acc:o00757] Measured 8223.39 8732.25 1.06188
mad protein (max dimerizer). [swissprot;acc:q05195] Ranked High confidence 228 204.333 1.11583
nadph oxidase 4. [refseq;acc:nm_016931] Low confidence 210.413 201.035 1.04665
proto-oncogene tyrosine-protein kinase abl1 (ec 2.7.1.112) (p150) (c-abl). [swissprot;acc:p00519] Measured High confidence 6417.18 7859.59 1.22477
ras-related protein r-ras2 (ras-like protein tc21) (teratocarcinoma oncogene). [swissprot;acc:p17082] Squared Low confidence 50402.7 46184.6 1.09133
signal recognition particle 9 kda protein (srp9). [swissprot;acc:p49458] Rooted High confidence 53.5956 60.465 1.12817

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/