MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1914 to 1963 of 3228 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	red	green	network_comparison
1914	melanoma antigen recognized by t cells 2. [refseq;acc:nm_018194]	6858.84	7287.27	1.06246
1915	5-aminolevulinic acid synthase, nonspecific, mitochondrial precursor (ec 2.3.1.37) (delta-aminolevulinate synthase) (delta-ala synthetase) (alas-h). [swissprot;acc:p13196]
1916	calcium-binding mitochondrial carrier protein aralar2 (solute carrier family 25, member 13) (citrin). [swissprot;acc:q9ujs0]
1917	acyl carrier protein, mitochondrial precursor (acp) (nadh-ubiquinone oxidoreductase 9.6 kda subunit) (ci-sdap). [swissprot;acc:o14561]
1918	seven in absentia homolog 1. [refseq;acc:nm_003031]	5394.24	5730.73	1.06238
1919	hydroxyindole o-methyltransferase (ec 2.1.1.4) (hiomt) (acetylserotonin o-methyltransferase) (asmt). [swissprot;acc:p46597]	5444.6	5783.95	1.06233
1920	basic proline-rich peptide p-e (ib-9). [swissprot;acc:p02811]	6262.66	6652.85	1.0623
1921	salivary proline-rich protein po (allele k) [contains: peptide p-d] (fragment). [swissprot;acc:p10162]
1922	hsp90 co-chaperone cdc37 (hsp90 chaperone protein kinase-targeting subunit) (p50cdc37). [swissprot;acc:q16543]	5567.41	5914.05	1.06226
1923	brain protein 16. [refseq;acc:nm_016458]	5774.02	6133.01	1.06217
1924	transcriptional adaptor 3-like isoform a. [refseq;acc:nm_006354]	7260.23	7711.3	1.06213
1925	bromodomain containing 7; bromodomain protein; bromodomain-containing 7. [refseq;acc:nm_013263]		7711.29
1926	frg1 protein (fshd region gene 1 protein). [swissprot;acc:q14331]		7711.3
1927	transcriptional adapter 2-like (ada2-like protein) (kl04p). [swissprot;acc:o75478]
1928	son of sevenless protein homolog 1 (sos-1). [swissprot;acc:q07889]	7514.8	7980.22	1.06193
1929	pxr2b protein. [refseq;acc:nm_016559]	6996.51	7429.18	1.06184
1930	p28 ing5. [refseq;acc:nm_032329]	5784.06	6141.48	1.06179
1931	ring finger protein 25 (ec 6.3.2.-). [swissprot;acc:q96bh1]	9946.21	9367.66	1.06176
1932	hepatocyte growth factor-regulated tyrosine kinase substrate; human growth factor-regulated tyrosine kinase substrate. [refseq;acc:nm_004712]	10300	9701.33	1.06171
1933	conserved oligomeric golgi complex component 7. [swissprot;acc:p83436]
1934	transducin beta-like 2 protein (ws beta-transducin repeats protein) (ws-betatrp) (williams-beuren syndrome chromosome region 13 protein). [swissprot;acc:q9y4p3]	5949.31	6313.1	1.06115
1935	serine palmitoyltransferase 1 (ec 2.3.1.50) (long chain base biosynthesis protein 1) (lcb 1) (serine-palmitoyl-coa transferase 1) (spt 1) (spt1). [swissprot;acc:o15269]	6167.29	6544.12	1.0611
1936	williams-beuren syndrome critical region protein 20 copy b. [refseq;acc:nm_145645]	5171.45	5486.96	1.06101
1937	williams beuren syndrome critical region 20a isoform 2; nol1/nop2/sun gene family member; williams-beuren syndrome critical region protein 20 copy a; williams beuren syndrome chromosome region 20. [refseq;acc:nm_018044]
1938	williams beuren syndrome chromosome region 20c isoform 1. [refseq;acc:nm_032158]
1939	brca1-associated ring domain protein 1 (bard-1). [swissprot;acc:q99728]	5669.9	6015.75	1.061
1940	m-phase inducer phosphatase 3 (ec 3.1.3.48) (dual specificity phosphatase cdc25c). [swissprot;acc:p30307]	4450.17	4721.37	1.06094
1941	rac gtpase activating protein 1; gtpase activating protein. [refseq;acc:nm_013277]	5521.07	5856.93	1.06083
1942	pre-mrna cleavage factor i, 59 kda subunit. [refseq;acc:nm_024811]	5805.06	6158.16
1943	p300/cbp-associated factor (ec 2.3.1.-) (p/caf) (histone acetylase pcaf). [swissprot;acc:q92831]	7210.87	7649.23	1.06079
1944	general control of amino acid synthesis protein 5-like 2 (ec 2.3.1.-) (histone acetyltransferase gcn5) (hsgcn5). [swissprot;acc:q92830]	7210.64	7648.94
1945	cofilin, non-muscle isoform (18 kda phosphoprotein) (p18). [swissprot;acc:p23528]	6230.21	6608.64	1.06074
1946	cofilin, muscle isoform (cofilin 2). [swissprot;acc:q9y281]
1947	transcription initiation factor tfiid 100 kda subunit (tafii-100) (tafii100). [swissprot;acc:q15542]	7195.76	7632.83
1948	destrin (actin-depolymerizing factor) (adf). [swissprot;acc:p18282]	6230.21	6608.64
1949	ubiquitin fusion degradation protein 1 homolog (ub fusion protein 1). [swissprot;acc:q92890]
1950	glutaminyl-trna synthase (glutamine-hydrolyzing)-like 1. [refseq;acc:nm_018292]	5888.32	6245.89	1.06073
1951	fatty-acid amide hydrolase (ec 3.1.-.-) (oleamide hydrolase) (anandamide amidohydrolase). [swissprot;acc:o00519]
1952	coactosin-like protein. [swissprot;acc:q14019]
1953	uracil-dna glycosylase, mitochondrial precursor (ec 3.2.2.-) (udg). [swissprot;acc:p13051]
1954	probable glutamyl-trna(gln) amidotransferase subunit b, mitochondrial precursor (ec 6.3.5.-) (glu-adt subunit b) (cytochrome oxidase assembly factor pet112 homolog). [swissprot;acc:o75879]
1955	28s ribosomal protein s16, mitochondrial precursor (mrp-s16) (cgi- 132). [swissprot;acc:q9y3d3]	5195.3	5510.67	1.0607
1956	nin one binding protein; adenocarcinoma antigen recognized by t lymphocytes 4. [refseq;acc:nm_014062]	4689.78	4973.44	1.06048
1957	transcription initiation factor tfiid 20/15 kda subunits (tafii- 20/tafii-15) (tafii20/tafii15). [swissprot;acc:q16514]	7019.78	7444.06	1.06044
1958	splicing coactivator subunit srm300; rna binding protein; at-rich element binding factor. [refseq;acc:nm_016333]	5448.35	5777.35	1.06039
1959	splicing factor u2af 35 kda subunit (u2 auxiliary factor 35 kda subunit) (u2 snrnp auxiliary factor small subunit). [swissprot;acc:q01081]
1960	rna helicase-related protein; rna helicase-like protein; sf3b125 dead-box protein. [refseq;acc:nm_007372]
1961	splicing factor u2af 65 kda subunit (u2 auxiliary factor 65 kda subunit) (u2 snrnp auxiliary factor large subunit) (hu2af(65)). [swissprot;acc:p26368]
1962	c-jun-amino-terminal kinase interacting protein 3 (jnk-interacting protein 3) (jip-3) (jnk map kinase scaffold protein 3) (mitogen- activated protein kinase 8-interacting protein 3). [swissprot;acc:q9upt6]	5941.24	6297.78	1.06001
1963	phenylalanine-4-hydroxylase (ec 1.14.16.1) (pah) (phe-4- monooxygenase). [swissprot;acc:p00439]	4374.32	4126.96	1.05994

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.