Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1844 to 1893 of 3228 in total 
Value Type	Measured
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	green	network_comparison	
1844	bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 1 (paps synthethase 1) (papss 1) (sulfurylase kinase 1) (sk1) (sk 1) [includes: sulfate adenylyltransferase (ec 2.7.7.4) (sulfate adenylate transferase) (sat) (atp-sulfurylase); adenylylsulfate kinase (ec 2.7.1.25) (adenylylsulfate 3'-phosphotransferase) (aps kinase) (adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)]. [source:swissprot;acc:o43252]	3591.95	3375.34	1.06417	
1845	nadph-cytochrome p450 reductase (ec 1.6.2.4) (cpr) (p450r). [source:swissprot;acc:p16435]	3591.95	3375.34	1.06417	
1846	cholinephosphate cytidylyltransferase b (ec 2.7.7.15) (phosphorylcholine transferase b) (ctp:phosphocholine cytidylyltransferase b) (ct b) (cct b) (cct-beta). [source:swissprot;acc:q9y5k3]	3591.95	3375.34	1.06417	
1847	glutamine synthetase (ec 6.3.1.2) (glutamate--ammonia ligase). [source:swissprot;acc:p15104]	6215.55	6613.46	1.06402	
1848	heat shock protein hsp 90-alpha (hsp 86). [source:swissprot;acc:p07900]	5746.06	6113.79	1.064	
1849	arginase ii, mitochondrial precursor (ec 3.5.3.1) (non-hepatic arginase) (kidney-type arginase). [source:swissprot;acc:p78540]	6267.93	6668.72	1.06394	
1850	protein kinase c binding protein 1 (rack7) (cutaneous t-cell lymphoma associated antigen se14-3) (ctcl tumor antigen se14-3) (zinc finger mynd domain containing protein 8). [source:swissprot;acc:q9ulu4]	6158.6	6551.94	1.06387	
1851	adenovirus 5 e1a-binding protein (bs69 protein). [source:swissprot;acc:q15326]	6156.28	6549.03	1.0638	
1852	arginase 1 (ec 3.5.3.1) (liver-type arginase). [source:swissprot;acc:p05089]	6271.17	6670.97	1.06375	
1853	keratin associated protein 9.2. [source:refseq;acc:nm_031961]	6076.65	6463.64	1.06368	
1854	keratin associated protein 4-10; keratin associated protein 4.10. [source:refseq;acc:nm_033060]	6076.66	6463.14	1.0636	
1855	keratin associated protein 4-2; keratin associated protein 4.2. [source:refseq;acc:nm_033062]	6076.66	6463.14	1.0636	
1856	keratin associated protein 4.3 (fragment). [source:sptrembl;acc:q9byr4]	6076.66	6463.14	1.0636	
1857	keratin associated protein 2-4; keratin associated protein 2.4. [source:refseq;acc:nm_033184]	6076.66	6463.15	1.0636	
1858	keratin associated protein 4-14; keratin associated protein 4.14. [source:refseq;acc:nm_033059]	6076.66	6463.13	1.0636	
1859	keratin associated protein 4.9 (fragment). [source:sptrembl;acc:q9byq8]	6076.66	6463.13	1.0636	
1860	keratin associated protein 4-12; keratin associated protein 4.12. [source:refseq;acc:nm_031854]	6076.66	6463.13	1.0636	
1861	keratin associated protein 1.5. [source:refseq;acc:nm_031957]	6076.66	6463.14	1.0636	
1862	star-related lipid transfer protein 6 (stard6) (start domain- containing protein 6). [source:swissprot;acc:p59095]	6076.66	6463.13	1.0636	
1863	keratin, ultra high-sulfur matrix protein b (uhs keratin b) (uhs kerb). [source:swissprot;acc:o75690]	6076.66	6463.14	1.0636	
1864	keratin, ultra high-sulfur matrix protein a (uhs keratin a) (uhs kera). [source:swissprot;acc:p26371]	6076.66	6463.14	1.0636	
1865	star-related lipid transfer protein 5 (stard5) (start domain- containing protein 5). [source:swissprot;acc:q9nsy2]	6076.66	6463.12	1.0636	
1866	keratin associated protein 4.4. [source:refseq;acc:nm_032524]	6076.66	6463.14	1.0636	
1867	alpha-parvin (calponin-like integrin-linked kinase binding protein) (ch-ilkbp). [source:swissprot;acc:q9nvd7]	6076.66	6463.12	1.0636	
1868	pinch protein (particularly interesting new cys-his protein) (lim and senescent cell antigen-like domains 1). [source:swissprot;acc:p48059]	6076.66	6463.12	1.0636	
1869	integrin-linked protein kinase 1 (ec 2.7.1.-) (ilk-1) (59 kda serine/threonine protein kinase) (p59ilk). [source:swissprot;acc:q13418]	6076.66	6463.12	1.0636	
1870	star-related lipid transfer protein 4 (stard4) (start domain- containing protein 4). [source:swissprot;acc:q96dr4]	6076.66	6463.13	1.0636	
1871	ras suppressor protein 1 (rsu-1) (rsp-1). [source:swissprot;acc:q15404]	6076.66	6463.12	1.0636	
1872	ras-gtpase-activating protein binding protein 1 (gap sh3-domain binding protein 1) (g3bp-1). [source:swissprot;acc:q13283]	6076.66	6463.12	1.0636	
1873	40s ribosomal protein s11. [source:swissprot;acc:p04643]	3618.46	3402.09	1.0636	
1874	ras-gtpase-activating protein binding protein 2 (gap sh3-domain binding protein 2) (g3bp-2). [source:swissprot;acc:q9un86]	6076.66	6463.12	1.0636	
1875	keratin associated protein 1-3; keratin associated protein 1.3. [source:refseq;acc:nm_030966]	6076.66	6463.14	1.0636	
1876	espin. [source:refseq;acc:nm_031475]	6076.66	6463.12	1.0636	
1877	cytochrome p450 2d6 (ec 1.14.14.1) (cypiid6) (p450-db1) (debrisoquine 4-hydroxylase). [source:swissprot;acc:p10635]	6076.66	6463.12	1.0636	
1878	pleckstrin homology domain containing, family c (with ferm domain) member 1; mitogen inducible 2; kindlin 2. [source:refseq;acc:nm_006832]	6076.66	6463.12	1.0636	
1879	lim and senescent cell antigen-like domains 2; ilk-binding protein. [source:refseq;acc:nm_017980]	6076.66	6463.12	1.0636	
1880	d(4) dopamine receptor (d(2c) dopamine receptor). [source:swissprot;acc:p21917]	6076.66	6463.12	1.0636	
1881	keratin associated protein 9-4; keratin associated protein 9.4. [source:refseq;acc:nm_033191]	6076.68	6462.56	1.0635	
1882	eukaryotic translation initiation factor 2 subunit 3 (eukaryotic translation initiation factor 2 gamma subunit) (eif-2-gamma). [source:swissprot;acc:p41091]	5490.24	5838.67	1.06346	
1883	26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [source:swissprot;acc:q99460]	5826	6195.48	1.06342	
1884	adhesion regulating molecule 1 precursor (110 kda cell membrane glycoprotein) (gp110). [source:swissprot;acc:q16186]	5826	6195.48	1.06342	
1885	ubiquitin carboxyl-terminal hydrolase isozyme l5 (ec 3.4.19.12) (uch- l5) (ubiquitin thiolesterase l5) (ubiquitin c-terminal hydrolase uch37) (cgi-70) (ad-019). [source:swissprot;acc:q9y5k5]	5826	6195.48	1.06342	
1886	rna polymerase ii subunit 5-mediating protein (rpb5-mediating protein). [source:swissprot;acc:o94763]	5826	6195.48	1.06342	
1887	protein regulator of cytokinesis 1; protein regulating cytokinesis 1. [source:refseq;acc:nm_003981]	5438.6	5783.11	1.06335	
1888	bromodomain-containing protein 4 (hunk1 protein). [source:swissprot;acc:o60885]	5438.6	5783.11	1.06335	
1889	testis-specific bromodomain protein. [source:refseq;acc:nm_001726]	5438.68	5783.2	1.06335	
1890	nag14 protein. [source:refseq;acc:nm_022143]	5438.6	5783.11	1.06335	
1891	bromodomain-containing protein 3 (ring3-like protein). [source:swissprot;acc:q15059]	5438.18	5782.62	1.06334	
1892	bromodomain-containing protein 2 (ring3 protein) (o27.1.1). [source:swissprot;acc:p25440]	5438.52	5783.01	1.06334	
1893	acid ceramidase precursor (ec 3.5.1.23) (acylsphingosine deacylase) (n-acylsphingosine amidohydrolase) (ac) (putative 32 kda heart protein) (php32). [source:swissprot;acc:q13510]	6830.4	7261.98	1.06319	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/