MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Gene	description	Value Type	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red

Results: HTML CSV LaTeX

Showing element 101 to 150 of 77072 in total

Filtered  : 0

description	Value Type	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	Rooted	347	Subtracted	1.2218	High confidence	31.1453	32.3671
		376	Divided	1.03923
		396	Subtracted	1.7724	Low confidence	25.4539	27.2263
		442	Divided	1.06963
3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]	Measured	264	Subtracted	115.5	High confidence	1721.76	1837.26
		346	Divided	1.06708
		406	Subtracted	116.24	Low confidence	1500.63	1616.87
		459	Divided	1.07746
	Ranked	473	Subtracted	86.7	High confidence	10243.1	10156.4
		478	Divided	1.00854
		614		1.03221	Low confidence	10984.2	10641.4
			Subtracted	342.8
	Squared	239		175.74	High confidence	6794.39	6970.13
		397		266.01	Low confidence	5250.39	5516.4
		455	Divided	1.02587	High confidence	6794.39	6970.13
		655		1.05066	Low confidence	5250.39	5516.4
	Rooted	339	Subtracted	1.257	High confidence	26.8141	28.0711
		357	Divided	1.04688
		446	Subtracted	1.5871	Low confidence	24.5318	26.1189
		461	Divided	1.0647
4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	Measured	121		1.3721	High confidence	14.3333	19.6667
		460	Subtracted	5.3334
		789		9.81	Low confidence	3822.12	3831.93
		815	Divided	1.00257
	Ranked	277	Subtracted	855	High confidence	19704.7	18849.7
		369	Divided	1.04536
		384	Subtracted	665.7	Low confidence	10788.6	11454.3
		481	Divided	1.0617
	Squared	232		1.34278	High confidence	0.145878	0.108639
		268	Subtracted	680.6	Low confidence	32991.9	33672.5
		492		0.037239	High confidence	0.145878	0.108639
		740	Divided	1.02063	Low confidence	32991.9	33672.5
	Rooted	36		1.96964	High confidence	2.18581	4.30525
		267	Subtracted	2.11944
		643		0.7323	Low confidence	33.079	32.3467
		680	Divided	1.02264
40s ribosomal protein s10. [swissprot;acc:p46783]	Measured	513		1.05788		1135.73	1201.47
		537	Subtracted	65.74
	Ranked	357		750.5		13169.5	12419
		488	Divided	1.06043
	Squared	157	Subtracted	1480.93		5302.97	6783.9
		219	Divided	1.27926
	Rooted	436		1.07201		17.5674	18.8324
		508	Subtracted	1.265
40s ribosomal protein s12. [swissprot;acc:p25398]	Measured	575		53.51		2194.28	2140.77
		661	Divided	1.025
	Ranked	556	Subtracted	527.3		11494.2	12021.5
		560	Divided	1.04588
	Squared	323	Subtracted	472.5		20717.3	21189.8
		730	Divided	1.02281

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.