MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1630 to 1679 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	Hugo	description	Value Type
3163	CNOT3	ccr4-not transcription complex, subunit 3; not3 (negative regulator of transcription 3, yeast) homolog. [refseq;acc:nm_014516]	Ranked
			Squared
			Rooted
3164	TFAP2C	transcription factor ap-2 gamma (ap2-gamma) (activating enhancer- binding protein 2 gamma) (transcription factor erf-1). [swissprot;acc:q92754]	Measured
			Ranked
			Squared
			Rooted
3165	PIGS	gpi transamidase component pig-s (phosphatidylinositol-glycan biosynthesis, class s protein). [swissprot;acc:q96s52]	Measured
			Ranked
			Squared
			Rooted
3166	MTMR2	myotubularin-related protein 2 (ec 3.1.3.-). [swissprot;acc:q13614]	Measured
			Ranked
			Squared
			Rooted
3167	ZW10	centromere/kinetochore protein zw10 homolog. [swissprot;acc:o43264]	Measured
			Ranked
			Squared
			Rooted
3168	TMED2	cop-coated vesicle membrane protein p24 precursor (p24a). [swissprot;acc:q15363]	Measured
			Ranked
			Squared
			Rooted
3169	NFX1	transcriptional repressor nf-x1 (ec 6.3.2.-) (nuclear transcription factor, x box-binding, 1). [swissprot;acc:q12986]	Measured
			Ranked
			Squared
			Rooted
3170	EVI1	ecotropic virus integration 1 site protein. [swissprot;acc:q03112]	Measured
			Ranked
			Squared
			Rooted
3171	CCNT2	cyclin t2. [swissprot;acc:o60583]	Measured
			Ranked
			Squared
			Rooted
3172	LIPE	hormone sensitive lipase (ec 3.1.1.-) (hsl). [swissprot;acc:q05469]	Measured
			Ranked
			Squared
			Rooted
3173	PIK3C3	phosphoinositide-3-kinase, class 3; vps34; phosphatidylinositol 3-kinase, class 3. [refseq;acc:nm_002647]	Measured
			Ranked
			Squared
			Rooted
3174	TM9SF3	transmembrane 9 superfamily protein member 3 precursor (sm-11044 binding protein) (ep70-p-iso). [swissprot;acc:q9hd45]	Measured
			Ranked
			Squared
			Rooted
3175	TUBA3D	tubulin alpha-3/alpha-7 chain (alpha-tubulin 3/7). [swissprot;acc:p05214]	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.