Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered Gene Value Type Network Comparison Type Rank description Interaction Map green network_comparison red
Results: HTML CSV LaTeX Showing element 51 to 100 of 77072 in total
Filtered  : 0
Value Type  : Measured
Network Comparison Type  : Divided
Rank
description
Interaction Map
green
network_comparison
red
26 fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402] High confidence 662 4.3268 153
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] Low confidence 47 3.04255 143
27 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] 35.5 2.97183 105.5
phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086] High confidence 139 4.10072 570
28 beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938]
melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] Low confidence 35.5 2.97183 105.5
29 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281] High confidence 434.911 3.90833 111.278
30 dystrophin. [swissprot;acc:p11532] 111.739 3.82335 427.217
melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] Low confidence 35.5 2.97183 105.5
31 dok-like protein. [refseq;acc:nm_024872] High confidence 0.00001 3500000 35
hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] Low confidence 35.5 2.97183 105.5
32 cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336] High confidence 184 3.25 598
melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] Low confidence 35.5 2.97183 105.5
33 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893] High confidence 39.8063 3.15402 12.6208
melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] Low confidence 35.5 2.97183 105.5
34 glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] High confidence 47 3.04255 143
melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] Low confidence 35.5 2.97183 105.5
35 adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236] High confidence 1377 2.99674 459.5
melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] Low confidence 35.5 2.97183 105.5
36 heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174] High confidence 56 2.80357 157
melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] Low confidence 35.5 2.97183 105.5
37 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] High confidence 934.348 2.79409 334.401
melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] Low confidence 35.5 2.97183 105.5
38 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]
zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623] High confidence 120.429 2.65727 320.012
39 melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365] Low confidence 35.5 2.97183 105.5
microtubule-associated protein, rp/eb family, member 2; t-cell activation protein, eb1 family; apc-binding protein eb1. [refseq;acc:nm_014268] High confidence 192.295 2.50878 482.426
40 melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355] Low confidence 35.5 2.97183 105.5
nanos (fragment). [sptrembl;acc:q8wy41] High confidence 151 2.49669 377
41 melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363] Low confidence 35.5 2.97183 105.5
nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] High confidence 645 2.42481 266
42 melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366] Low confidence 35.5 2.97183 105.5
presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341] High confidence 86.9525 2.36266 205.439
43 elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897] 587.988 2.2301 263.66
melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1] Low confidence 35.5 2.97183 105.5
44 acyl-coa dehydrogenase, short/branched chain specific, mitochondrial precursor (ec 1.3.99.-) (sbcad) (2-methyl branched chain acyl-coa dehydrogenase) (2-mebcad) (2-methylbutyryl-coenzyme a dehydrogenase) (2-methylbutyryl-coa dehydrogenase). [swissprot;acc:p45954] High confidence 98.5074 2.16837 45.4292
neurogenic locus notch homolog protein 1 precursor (notch 1) (hn1) (translocation-associated notch protein tan-1). [swissprot;acc:p46531] Low confidence 0.00001 28600000 286
45 neurogenic locus notch homolog protein 2 precursor (notch 2) (hn2). [swissprot;acc:q04721]
tigger transposable element derived 6. [refseq;acc:nm_030953] High confidence 438.605 2.1673 202.374
46 ephrin type-b receptor 4 precursor (ec 2.7.1.112) (tyrosine-protein kinase receptor htk). [swissprot;acc:p54760] Low confidence 67 2.79167 24
tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208] High confidence 438.035 2.16674 202.163
47 tenascin-x precursor (tn-x) (hexabrachion-like). [swissprot;acc:p22105] Low confidence 776.89 2.50526 310.103
tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702] High confidence 438.016 2.16672 202.156
48 deltex homolog 1; hdx-1. [refseq;acc:nm_004416] 403.196 2.15895 870.482
pnas-129. [sptrembl;acc:q9bxv8] Low confidence 151.073 2.42708 366.666
49 nadh-ubiquinone oxidoreductase 13 kda-b subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-13kd-b) (ci-13kd-b) (complex i subunit b13). [swissprot;acc:q16718] 645 2.42481 266
selenide,water dikinase 2 (ec 2.7.9.3) (selenophosphate synthetase 2) (selenium donor protein 2). [swissprot;acc:q99611] High confidence 151 2.09722 72
50 latrophilin 2; lectomedin-1; latrophilin homolog 2 (cow). [refseq;acc:nm_012302] Low confidence 111 2.36036 262
transcription factor 4 (immunoglobulin transcription factor 2) (itf-2) (sl3-3 enhancer factor 2) (sef-2). [swissprot;acc:p15884] High confidence 21 2.09524 44

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/