MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Hugo	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1530 to 1579 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	Hugo	description	red	green	network_comparison
1530	MLLT4	af-6 protein. [swissprot;acc:p55196]	218.733	214.98	1.01746
1531	CRIM1	cysteine-rich motor neuron 1; cysteine-rich repeat-containing protein s52 precursor. [refseq;acc:nm_016441]	217.025	213.304	1.01744
1532	RBM10	rna-binding protein 10 (rna binding motif protein 10) (dxs8237e). [swissprot;acc:p98175]	228.419	232.376	1.01732
1533	CYCS	cytochrome c. [swissprot;acc:p00001]
1534	HS6ST2	heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174]
1535	HS6ST1	heparan sulfate 6-o-sulfotransferase; heparan-sulfate 6-sulfotransferase. [refseq;acc:nm_004807]
1536	FA2H	fatty acid hydroxylase domain containing 1. [refseq;acc:nm_024306]
1537	WBP11	ww domain binding protein 11; npw38-binding protein npwbp; sh3 domain-binding protein snp70. [refseq;acc:nm_016312]
1538	ELAC2	elac homolog 2; putative prostate cancer susceptibility protein; elac (e. coli) homolog 2. [refseq;acc:nm_018127]
1539	RBM5	rna-binding protein 5 (rna binding motif protein 5) (putative tumor suppressor luca15) (g15 protein). [swissprot;acc:p52756]
1540	ATG5	autophagy protein 5-like (apg5-like) (apoptosis-specific protein). [swissprot;acc:q9h1y0]	240.077	236.015	1.01721
1541	MYB	myb proto-oncogene protein (c-myb). [swissprot;acc:p10242]	222.672	218.92	1.01714
1542	TMLHE	trimethyllysine dioxygenase, mitochondrial precursor (ec 1.14.11.8) (epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (tml-alpha- ketoglutarate dioxygenase) (tml hydroxylase) (tml dioxygenase) (tmld). [swissprot;acc:q9nvh6]	213.546	209.965	1.01706
1543	ERAL1	gtp-binding protein era homolog (hera) (fragment). [swissprot;acc:o75616]
1544	NR2E1	orphan nuclear receptor nr2e1 (nuclear receptor tlx) (tailless homolog) (tll) (htll). [swissprot;acc:q9y466]	219.762	216.081	1.01704
1545	NR2C1	orphan nuclear receptor tr2. [swissprot;acc:p13056]	219.76	216.083	1.01702
1546	ASS1	argininosuccinate synthase (ec 6.3.4.5) (citrulline--aspartate ligase). [swissprot;acc:p00966]	217.769	221.474	1.01701
1547	MYBL2	myb-related protein b (b-myb). [swissprot;acc:p10244]	222.541	218.823	1.01699
1548	MYBL1	myb-related protein a (a-myb). [swissprot;acc:p10243]	222.512	218.802	1.01696
1549	DCTN2	dynactin complex 50 kda subunit (50 kda dynein-associated polypeptide) (dynamitin) (dctn-50) (dynactin 2). [swissprot;acc:q13561]	225.159	221.424	1.01687
1550	SLC25A6	adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236]
1551	SLC25A4	adp,atp carrier protein, heart/skeletal muscle isoform t1 (adp/atp translocase 1) (adenine nucleotide translocator 1) (ant 1). [swissprot;acc:p12235]
1552	SLC25A5	adp,atp carrier protein, fibroblast isoform (adp/atp translocase 2) (adenine nucleotide translocator 2) (ant 2). [swissprot;acc:p05141]
1553	AHCY	adenosylhomocysteinase (ec 3.3.1.1) (s-adenosyl-l-homocysteine hydrolase) (adohcyase). [swissprot;acc:p23526]	215.389	211.833	1.01679
1554	CTBP1	c-terminal binding protein 1 (ctbp1). [swissprot;acc:q13363]	196.215	193.018	1.01656
1555	PASK	pas domain containing serine/threonine kinase; pas-serine/threonine kinase. [refseq;acc:nm_015148]	196.192	192.996
1556	BCL6	b-cell lymphoma 6 protein (bcl-6) (zinc finger protein 51) (laz-3 protein) (bcl-5). [swissprot;acc:p41182]
1557	SNAI2	zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623]
1558	CTBP2	c-terminal binding protein 2 (ctbp2). [swissprot;acc:p56545]	196.171	192.977	1.01655
1559	BCL6B	b-cell cll/lymphoma 6, member b (zinc finger protein); zinc finger protein 62. [refseq;acc:nm_181844]	196.191	192.996
1560	GATAD2A	p66 alpha. [refseq;acc:nm_017660]	167.687	170.455	1.01651
1561	GATAD2B	transcription repressor p66 beta component of the mecp1 complex. [refseq;acc:nm_020699]
1562	no value	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]
1563	ATP5C1	atp synthase gamma chain, mitochondrial precursor (ec 3.6.3.14). [swissprot;acc:p36542]	218.277	214.739	1.01648
1564	ATP5O	atp synthase oligomycin sensitivity conferral protein, mitochondrial precursor (ec 3.6.3.14) (oscp). [swissprot;acc:p48047]
1565	EIF3K	eukaryotic translation initiation factor 3 subunit 11 (eif-3 p25) (eif3k) (muscle specific gene m9 protein) (ptd001) (hspc029) (arg134). [swissprot;acc:q9ubq5]	221.128	224.767	1.01646
1566	SLMO1	erythroid differentiation and denucleation factor 1. [swissprot;acc:o60584]
1567	BBS7	bardet-biedl syndrome 7 protein isoform a; bbs2-like 1. [refseq;acc:nm_176824]
1568	no value	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
1569		lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]
1570	SLMO2	protein c20orf45 (cgi-107). [swissprot;acc:q9y3b1]
1571	EIF3EIP	eukaryotic translation initiation factor 3 subunit 6 interacting protein (hspc021/hspc025). [swissprot;acc:q9y262]
1572	RBM7	putative rna-binding protein 7 (rna binding motif protein 7). [swissprot;acc:q9y580]
1573	R3HDM1	r3h domain protein 1. [swissprot;acc:q15032]	218.105	214.573
1574	TMF1	tata element modulatory factor (tmf). [swissprot;acc:p82094]	222.585	218.982	1.01645
1575	SCYL1	scy1-like 1; telomerase regulation-associated protein; ht019 protein; telomerase regulation-associated protein; n-terminal kinase-like protein; teratoma-associated tyrosine kinase; n-terminal kinase-like. [refseq;acc:nm_020680]
1576	NUP98	nuclear pore complex protein nup98 (nucleoporin nup98) (98 kda nucleoporin). [swissprot;acc:p52948]
1577	AMMECR1	ammecr1 protein. [refseq;acc:nm_015365]
1578	RAE1	mrna-associated protein mrnp 41 (rae1 protein homolog). [swissprot;acc:p78406]
1579	TATDN1	cda11 protein. [refseq;acc:nm_032026]	213.181	209.732	1.01644

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.