MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Rank	description	Value Type	Network Comparison Type	red	Interaction Map	network_comparison	green	Filtered

Results: HTML CSV LaTeX

Showing element 301 to 350 of 3228 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	red	network_comparison	green
301	cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551]	13768.2	1.20078	11466
302	pallidin; pallid (mouse) homolog, pallidin. [refseq;acc:nm_012388]	5894.75	1.19999	7073.65
303	serine/threonine protein phosphatase pp1-gamma catalytic subunit (ec 3.1.3.16) (pp-1g). [swissprot;acc:p36873]	22268.8	1.1998	18560.4
304	pre-mrna processing factor 31 homolog; pre-mrna processing factor 31 homolog (yeast). [refseq;acc:nm_015629]	4855.46	1.19958	5824.52
305	odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260]	3856.29	1.19912	4624.15
306	pnas-18. [sptrembl;acc:q9bzu3]	13680.5	1.19903	11409.6
307	t-complex protein 1, gamma subunit (tcp-1-gamma) (cct-gamma). [swissprot;acc:p49368]	12365.2	1.19892	14824.9
308	segment polarity protein dishevelled homolog dvl-1 (dishevelled-1) (dsh homolog 1). [swissprot;acc:o14640]	4977.09	1.19878	5966.44
309	segment polarity protein dishevelled homolog dvl-2 (dishevelled-2) (dsh homolog 2). [swissprot;acc:o14641]	4977.8	1.19855	5966.14
310	squamous cell carcinoma antigen recognized by t cells 1; u4/u6.u5 tri-snrnp-associated 110 kda protein; ige autoantigen; sart1(259) protein; sart1(800) protein. [refseq;acc:nm_005146]	4909.79	1.19736	5878.79
311	segment polarity protein dishevelled homolog dvl-3 (dishevelled-3) (dsh homolog 3). [swissprot;acc:q92997]	4981.52	1.19734	5964.58
312	u6 snrna-associated sm-like protein lsm7. [swissprot;acc:q9uk45]	4598.21	1.19622	5500.48
313	protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236]	21644.2	1.1959	18098.7
314	type 1 protein phosphatase inhibitor. [refseq;acc:nm_025210]	21632.5	1.19583	18090
315	ribosome biogenesis regulatory protein homolog. [swissprot;acc:q15050]	21370.8	1.19413	17896.5
316	serine/threonine protein phosphatase pp1-alpha 1 catalytic subunit (ec 3.1.3.16) (pp-1a). [swissprot;acc:p08129]
317	adiponectin receptor 2. [refseq;acc:nm_024551]	3153.1	1.19329	3762.56
318	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	34190.9	1.19318	40795.8
319	ras-related gtp binding a; ras-related gtp-binding protein. [refseq;acc:nm_006570]	20911	1.19117	24908.5
320	ras-related gtp binding c; rag c protein. [refseq;acc:nm_022157]
321	ras-related gtp binding b short isoform; gtp-binding protein ragb. [refseq;acc:nm_006064]
322	anillin, actin binding protein (scraps homolog, drosophila); anillin (drosophila scraps homolog), actin binding protein. [refseq;acc:nm_018685]
323	u6 snrna-associated sm-like protein lsm4 (glycine-rich protein) (grp). [swissprot;acc:q9y4z0]	4620.76	1.1907	5501.94
324	deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]	28136.5	1.18912	33457.6
325	septin-like protein kiaa0202 (fragment). [swissprot;acc:q92599]	16177.9	1.18899	19235.4
326	atp-dependent rna helicase ddx24 (dead-box protein 24). [swissprot;acc:q9gzr7]	3432.96	1.18883	4081.21
327	septin 10 isoform 1. [refseq;acc:nm_144710]	16067.4	1.18839	19094.4
328	brain protein 44. [swissprot;acc:o95563]	15999.1	1.18801	19007.1
329	septin 7 (cdc10 protein homolog). [swissprot;acc:q16181]
330	septin 6. [swissprot;acc:q14141]	15959.9	1.1878	18957.1
331	pre-mrna cleavage complex ii protein pcf11 (fragment). [swissprot;acc:o94913]	20287.2	1.18751	17083.8
332	pleiotropic regulator 1 (prl1homolog, arabidopsis); pleiotropic regulator 1 (prl1, arabidopsis homolog). [refseq;acc:nm_002669]	5051.16	1.183	5975.51
333	nuclear matrix protein nmp200 related to splicing factor prp19. [refseq;acc:nm_014502]	5039.63	1.18299	5961.83
334	septin 4 (peanut-like protein 2) (brain protein h5) (cell division control-related protein 2) (hcdcrel-2) (bradeion beta) (ce5b3 beta) (cerebral protein-7) (hucep-7). [swissprot;acc:o43236]	14924.4	1.18298	17655.2
335	probable atp-dependent 61 kda nucleolar rna helicase (dead-box protein 21). [swissprot;acc:q9ny93]	3494.31	1.18181	4129.6
336	dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33]	3751.3	1.18128	4431.34
337	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	20446.1	1.18049	24136.4
338	homeobox protein hox-b4 (hox-2f) (hox-2.6). [swissprot;acc:p17483]
339	homeobox protein hox-c5 (hox-3d) (cp11). [swissprot;acc:q00444]
340	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
341	homeobox protein hox-d4 (hox-4b) (hox-5.1) (hho.c13). [swissprot;acc:p09016]
342	homeobox protein hox-b5 (hox-2a) (hho.c10) (hu-1). [swissprot;acc:p09067]
343	homeobox protein hox-a5 (hox-1c). [swissprot;acc:p20719]
344	homeobox protein hox-a4 (hox-1d) (hox-1.4). [swissprot;acc:q00056]
345	retinal short-chain dehydrogenase/reductase 3. [refseq;acc:nm_016246]
346	septin 1 (larp) (serologically defined breast cancer antigen ny-br- 24). [swissprot;acc:q8wyj6]	14229.2	1.17931	16780.7
347	enteropeptidase precursor (ec 3.4.21.9) (enterokinase). [swissprot;acc:p98073]	4991.02	1.17914	5885.09
348	splicing factor 3b subunit 2 (spliceosome associated protein 145) (sap 145) (sf3b150) (pre-mrna splicing factor sf3b 145 kda subunit). [swissprot;acc:q13435]
349	putative pre-mrna splicing factor rna helicase (deah box protein 15) (atp-dependent rna helicase #46). [swissprot;acc:o43143]	4714.85	1.17806	5554.38
350	sedlin. [swissprot;acc:o14582]	17396.9	1.17745	20483.9

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.