MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	Network Comparison Type	Hugo	description	Value Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 1425 to 1474 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Hugo	description	Value Type
3112	RAB11A	ras-related protein rab-11a (rab-11) (24kg) (yl8). [swissprot;acc:p24410]	Measured
			Ranked
			Squared
			Rooted
3113	NUTF2	nuclear transport factor 2 (ntf-2) (placental protein 15) (pp15). [swissprot;acc:p13662]	Measured
			Ranked
			Squared
			Rooted
3114	TSC22D1	regulatory protein tsc-22 (tgfb stimulated clone 22 homolog). [swissprot;acc:q15714]	Measured
			Ranked
			Squared
			Rooted
3115	STK24	serine/threonine protein kinase 24 (ec 2.7.1.37) (ste20-like kinase mst3) (mst-3) (mammalian ste20-like protein kinase 3). [swissprot;acc:q9y6e0]	Measured
			Ranked
			Squared
			Rooted
3116	CAB39L	mo25-like protein. [swissprot;acc:q9h9s4]	Measured
			Ranked
			Squared
			Rooted
3117	FNDC3A	ba203i16.1 (hypothetical protein kiaa0970). [sptrembl;acc:q9h1w1]	Measured
			Ranked
			Squared
			Rooted
3118	SMS	spermine synthase (ec 2.5.1.22) (spermidine aminopropyltransferase) (spmsy). [swissprot;acc:p52788]	Measured
			Ranked
			Squared
			Rooted
3119	no value	rab gdp dissociation inhibitor alpha (rab gdi alpha) (gdi-1) (xap-4) (oligophrenin 2). [swissprot;acc:p31150]	Measured
			Ranked
			Squared
			Rooted
3120	SCML2	sex comb on midleg-like 2; sex comb on midleg like 2. [refseq;acc:nm_006089]	Measured
			Ranked
			Squared
			Rooted
3121	GLRA2	glycine receptor alpha-2 chain precursor. [swissprot;acc:p23416]	Measured
			Ranked
			Squared
			Rooted
3122	PRPS2	ribose-phosphate pyrophosphokinase ii (ec 2.7.6.1) (phosphoribosyl pyrophosphate synthetase ii) (ppribp) (prs-ii). [swissprot;acc:p11908]	Measured
			Ranked
			Squared
			Rooted
3123	VAPA	vesicle-associated membrane protein-associated protein a (vamp- associated protein a) (vamp-a) (vap-a) (33 kda vamp-associated protein) (vap-33). [swissprot;acc:q9p0l0]	Measured
			Ranked
			Squared
			Rooted
3124	SAMHD1	sam domain and hd domain-containing protein 1 (dendritic cell-derived ifng-induced protein) (dcip) (monocyte protein 5) (mop-5). [swissprot;acc:q9y3z3]	Measured
			Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.