MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	network_comparison	red	green

Results: HTML CSV LaTeX

Showing element 1382 to 1431 of 1892 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
network_comparison  : 0
red  : 0
green  : 0

Rank	Hugo	description	Value Type
3101	no value	gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	Ranked
			Squared
			Rooted
3102	C19orf56	protein cgi-140 (protein ptd008) (my006 protein). [swissprot;acc:q9y284]	Measured
			Ranked
			Squared
			Rooted
3103	LIG1	dna ligase i (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p18858]	Measured
			Ranked
			Squared
			Rooted
3104	SNORD23	glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5]	Measured
			Ranked
			Squared
			Rooted
3105	TGFB1	transforming growth factor beta 1 precursor (tgf-beta 1). [swissprot;acc:p01137]	Measured
			Ranked
			Squared
			Rooted
3106	PTOV1	prostate tumor overexpressed gene 1; prostate tumor over expressed gene 1. [refseq;acc:nm_017432]	Measured
			Ranked
			Squared
			Rooted
3107	LYL1	lyl-1 protein (lymphoblastic leukemia derived sequence 1). [swissprot;acc:p12980]	Measured
			Ranked
			Squared
			Rooted
3108	SNX16	sorting nexin 16. [swissprot;acc:p57768]	Measured
			Ranked
			Squared
			Rooted
3109	WISP1	wnt1 inducible signaling pathway protein 1 isoform 1 precursor; wnt-1 signaling pathway protein 1; wnt1 signaling pathway protein 1; wnt-1 inducible signaling pathway protein 1. [refseq;acc:nm_003882]	Measured
			Ranked
			Squared
			Rooted
3110	RAB2A	ras-related protein rab-2a. [swissprot;acc:p08886]	Measured
			Ranked
			Squared
			Rooted
3111	STK3	serine/threonine protein kinase 3 (ec 2.7.1.37) (ste20-like kinase mst2) (mst-2) (mammalian ste20-like protein kinase 2) (serine/threonine protein kinase krs-1). [swissprot;acc:q13188]	Measured
			Ranked
			Squared
			Rooted
3112	RAB11A	ras-related protein rab-11a (rab-11) (24kg) (yl8). [swissprot;acc:p24410]	Measured
			Ranked
			Squared
			Rooted
3113	NUTF2	nuclear transport factor 2 (ntf-2) (placental protein 15) (pp15). [swissprot;acc:p13662]	Measured
			Ranked
			Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.