MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	Value Type	description	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1332 to 1381 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	Value Type	description
3088	YWHAE	Rooted	14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]
3089	PRKAR1A	Measured	camp-dependent protein kinase type i-alpha regulatory chain (tissue- specific extinguisher-1) (tse1). [swissprot;acc:p10644]
		Ranked
		Squared
		Rooted
3090	EZH1	Measured	enhancer of zeste homolog 1 (enx-2). [swissprot;acc:q92800]
		Ranked
		Squared
		Rooted
3091	MLX	Measured	transcription factor-like protein 4 (max-like bhlhzip protein) (bigmax protein) (mlx). [swissprot;acc:q9uh92]
		Ranked
		Squared
		Rooted
3092	DRG2	Measured	developmentally regulated gtp-binding protein 2 (drg 2). [swissprot;acc:p55039]
		Ranked
		Squared
		Rooted
3093	no value	Measured	ptd016 protein. [refseq;acc:nm_016125]
		Ranked
		Squared
		Rooted
3094	UBE2S	Measured	ubiquitin-conjugating enzyme e2-24 kda (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2-epf5). [swissprot;acc:q16763]
		Ranked
		Squared
		Rooted
3095	C10orf137	Measured	erythroid differentiation-related factor 1. [refseq;acc:nm_015608]
		Ranked
		Squared
		Rooted
3096	NPM3	Measured	nucleoplasmin 3. [swissprot;acc:o75607]
		Ranked
		Squared
		Rooted
3097	SEC23IP	Measured	sec23-interacting protein p125; phospholipase. [refseq;acc:nm_007190]
		Ranked
		Squared
		Rooted
3098	EZH2	Measured	enhancer of zeste homolog 2 (enx-1). [swissprot;acc:q15910]
		Ranked
		Squared
		Rooted
3099	CAV1	Measured	caveolin-1. [swissprot;acc:q03135]
		Ranked
		Squared
		Rooted
3100	no value	Measured	presenilin enhancer 2; hematopoietic stem/progenitor cells protein mds033. [refseq;acc:nm_172341]
		Ranked
		Squared
		Rooted
3101		Measured	gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.