Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank description Network Comparison Type Value Type Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 1730 to 1779 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
description
Network Comparison Type
green
red
network_comparison
865 zinc finger protein 174 (aw-1). [swissprot;acc:q15697] Subtracted 278.239 269.963 8.276
866 signal recognition particle 68 kda protein (srp68). [swissprot;acc:q9uhb9] Divided 212.806 221.306 1.03994
zinc finger imprinted 2. [swissprot;acc:q9nzv7] Subtracted 278.232 269.96 8.272
867 40s ribosomal protein s3a. [swissprot;acc:p49241] Divided 234.674 225.689 1.03981
zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022] Subtracted 278.223 269.956 8.267
868 diphosphomevalonate decarboxylase (ec 4.1.1.33) (mevalonate pyrophosphate decarboxylase) (mevalonate (diphospho)decarboxylase). [swissprot;acc:p53602] Divided 242.571 233.298 1.03975
zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58] Subtracted 278.223 269.956 8.267
869 exocyst complex component sec8. [swissprot;acc:q96a65] Divided 209.449 217.762 1.03969
zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028] Subtracted 278.221 269.955 8.266
870 transcription factor btf3 homolog 3. [swissprot;acc:q13892] Divided 203.832 211.908 1.03962
zinc finger protein 305. [swissprot;acc:o43309] Subtracted 278.219 269.954 8.265
871 cleavage and polyadenylation specificity factor, 100 kda subunit (cpsf 100 kda subunit) (fragment). [swissprot;acc:q9p2i0] Divided 114.552 110.2 1.03949
zinc finger protein 232. [swissprot;acc:q9uny5] Subtracted 278.218 269.954 8.264
872 heterogeneous nuclear ribonucleoprotein k (hnrnp k) (dc-stretch binding protein) (csbp) (transformation upregulated nuclear protein) (tunp). [swissprot;acc:q07244] Divided 233.272 224.413 1.03948
zinc finger protein 99. [refseq;acc:nm_032164] Subtracted 278.218 269.954 8.264
873 u4/u6 small nuclear ribonucleoprotein prp4 (u4/u6 snrnp 60 kda protein) (wd splicing factor prp4) (hprp4). [swissprot;acc:o43172] Divided 233.272 224.413 1.03948
zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771] Subtracted 278.217 269.954 8.263
874 5'-amp-activated protein kinase, gamma-1 subunit (ampk gamma-1 chain) (ampkg). [swissprot;acc:p54619] Divided 203.954 212.002 1.03946
zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6] Subtracted 278.215 269.953 8.262
875 5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646] Divided 203.954 212.002 1.03946
junction plakoglobin (desmoplakin iii). [swissprot;acc:p14923] Subtracted 215.653 223.906 8.253
876 5'-amp-activated protein kinase, catalytic alpha-1 chain (ec 2.7.1.-) (ampk alpha-1 chain). [swissprot;acc:q13131] Divided 203.954 212.002 1.03946
tax interaction protein 1. [refseq;acc:nm_014604] Subtracted 215.653 223.906 8.253
877 5'-amp-activated protein kinase, beta-2 subunit (ampk beta-2 chain). [swissprot;acc:o43741] Divided 203.954 212.002 1.03946
zinc finger protein 444; endothelial zinc finger protein 2. [refseq;acc:nm_018337] Subtracted 278.093 269.896 8.197
878 5'-amp-activated protein kinase, gamma-3 subunit (ampk gamma-3 chain) (ampk gamma3). [swissprot;acc:q9ugi9] Divided 203.954 212.002 1.03946
syntaxin 7. [swissprot;acc:o15400] Subtracted 209.012 217.181 8.169
879 5'-amp-activated protein kinase, beta-1 subunit (ampk beta-1 chain) (ampkb). [swissprot;acc:q9y478] Divided 203.954 212.002 1.03946
phenylalanyl-trna synthetase alpha chain (ec 6.1.1.20) (phenylalanine- -trna ligase alpha chain) (phers) (cml33). [swissprot;acc:q9y285] Subtracted 209.323 217.491 8.168
880 5'-amp-activated protein kinase, gamma-2 subunit (ampk gamma-2 chain) (ampk gamma2) (h91620p). [swissprot;acc:q9ugj0] Divided 203.954 212.002 1.03946
phenylalanine-trna synthetase. [refseq;acc:nm_006567] Subtracted 209.323 217.491 8.168
881 l-myc-1 proto-oncogene protein. [swissprot;acc:p12524] Divided 219.001 227.604 1.03928
transcription factor btf3 (rna polymerase b transcription factor 3). [swissprot;acc:p20290] Subtracted 203.814 211.961 8.147
882 mitochondrial import receptor subunit tom20 homolog (mitochondrial 20 kda outer membrane protein) (outer mitochondrial membrane receptor tom20). [swissprot;acc:q15388] 190.66 198.781 8.121
n-myc proto-oncogene protein. [swissprot;acc:p04198] Divided 219.008 227.601 1.03924
883 ga binding protein alpha chain (gabp-alpha subunit) (transcription factor e4tf1-60) (nuclear respiratory factor-2 subunit alpha). [swissprot;acc:q06546] 219.017 227.596 1.03917
peroxisomal farnesylated protein (33 kda housekeeping protein) (peroxin 19). [swissprot;acc:p40855] Subtracted 190.66 198.781 8.121
884 ga binding protein beta-2 chain (gabp-beta-2 subunit) (transcription factor e4tf1-47) (gapbp-2) (nuclear respiratory factor-2 subunit gamma). [swissprot;acc:q06545] Divided 219.017 227.596 1.03917
sirtuin 7; sir2-related protein type 7; sirtuin type 7; sirtuin (silent mating type information regulation 2, s.cerevisiae, homolog) 7; silent mating type information regulation 2, s.cerevisiae, homolog 7; sirtuin silent mating type information regulation 2 homolog 7 (s. cerevisiae). [refseq;acc:nm_016538] Subtracted 224.372 232.473 8.101
885 casein kinase ii beta chain (ck ii) (phosvitin) (g5a). [swissprot;acc:p13862]
nadh-ubiquinone oxidoreductase 23 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-23kd) (ci-23kd) (tyky subunit). [swissprot;acc:o00217] Divided 219.017 227.596 1.03917
886 elongation of very long chain fatty acids protein 1 (cgi-88). [swissprot;acc:q9bw60] 219.018
transcription factor btf3 homolog 3. [swissprot;acc:q13892] Subtracted 203.832 211.908 8.076
887 5'-amp-activated protein kinase, gamma-1 subunit (ampk gamma-1 chain) (ampkg). [swissprot;acc:p54619] 203.954 212.002 8.048
transducin beta-like 3; wd-repeat protein sazd. [refseq;acc:nm_006453] Divided 234.96 244.155 1.03913
888 5'-amp-activated protein kinase, catalytic alpha-2 chain (ec 2.7.1.-) (ampk alpha-2 chain). [swissprot;acc:p54646] Subtracted 203.954 212.002 8.048
nascent-polypeptide-associated complex alpha polypeptide. [refseq;acc:nm_005594] Divided 204.05 212.027 1.03909
889 5'-amp-activated protein kinase, catalytic alpha-1 chain (ec 2.7.1.-) (ampk alpha-1 chain). [swissprot;acc:q13131] Subtracted 203.954 212.002 8.048
alpha-nac protein. [sptrembl;acc:q9h009] Divided 204.053 212.028 1.03908
890 5'-amp-activated protein kinase, beta-2 subunit (ampk beta-2 chain). [swissprot;acc:o43741] Subtracted 203.954 212.002 8.048

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/