Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 12264 to 12313 of 12912 in total
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red  : 0.00001
green  : 0.00001
network_comparison  : 1
Rank
description
Value Type
3066 vascular endothelial growth factor a precursor (vegf-a) (vascular permeability factor) (vpf). [swissprot;acc:p15692] Rooted
3067 retinoic acid receptor rxr-beta. [swissprot;acc:p28702] Measured
Ranked
Squared
Rooted
3068 headcase homolog; hhdc for homolog of drosophila headcase. [refseq;acc:nm_016217] Measured
Ranked
Squared
Rooted
3069 bone morphogenetic protein 5 precursor (bmp-5). [swissprot;acc:p22003] Measured
Ranked
Squared
Rooted
3070 mam domain containing glycosylphosphatidylinositol anchor 1; glycosyl-phosphatidyl-inositol-mam. [refseq;acc:nm_153487] Measured
Ranked
Squared
Rooted
3071 serine/threonine kinase 38; serine threonine protein kinase. [refseq;acc:nm_007271] Measured
Ranked
Squared
Rooted
3072 pak1 interacting protein 1; pak1-interacting protein; pak/plc-interacting protein 1. [refseq;acc:nm_017906] Measured
Ranked
Squared
Rooted
3073 rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952] Measured
Ranked
Squared
Rooted
3074 tu12b1-ty protein. [refseq;acc:nm_016575] Measured
Ranked
Squared
Rooted
3075 ubiquitin carboxyl-terminal hydrolase 5 (ec 3.1.2.15) (ubiquitin thiolesterase 5) (ubiquitin-specific processing protease 5) (deubiquitinating enzyme 5) (isopeptidase t). [swissprot;acc:p45974] Measured
Ranked
Squared
Rooted
3076 placental protein 11 precursor (ec 3.4.21.-) (pp11). [swissprot;acc:p21128] Measured
Ranked
Squared
Rooted
3077 h2a histone family, member j isoform 1. [refseq;acc:nm_018267] Measured
Ranked
Squared
Rooted
3078 camp responsive element binding protein-like 2. [refseq;acc:nm_001310] Measured
Ranked
Squared
Rooted
3079 25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/