Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1132 to 1181 of 3228 in total 
Value Type	Ranked
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	green	network_comparison	
1132	apoptosis inhibitor 5; fibroblast growth factor 2-interacting factor 2; api5-like 1. [source:refseq;acc:nm_006595]	218.484	212.675	1.02731	
1133	sec13-related protein. [source:swissprot;acc:p55735]	218.484	212.675	1.02731	
1134	vacuolar atp synthase subunit g 3 (ec 3.6.3.14) (v-atpase g subunit 3) (vacuolar proton pump g subunit 3) (v-atpase 13 kda subunit 3). [source:swissprot;acc:q96lb4]	218.484	212.675	1.02731	
1135	vacuolar atp synthase subunit b, brain isoform (ec 3.6.3.14) (v-atpase b2 subunit) (vacuolar proton pump b isoform 2) (endomembrane proton pump 58 kda subunit) (ho57). [source:swissprot;acc:p21281]	218.484	212.675	1.02731	
1136	yeast sec31p homolog. [source:refseq;acc:nm_014933]	218.484	212.675	1.02731	
1137	vacuolar atp synthase subunit g 1 (ec 3.6.3.14) (v-atpase g subunit 1) (vacuolar proton pump g subunit 1) (v-atpase 13 kda subunit 1) (vacuolar atp synthase subunit m16). [source:swissprot;acc:o75348]	218.484	212.675	1.02731	
1138	vacuolar atp synthase subunit e (ec 3.6.3.14) (v-atpase e subunit) (vacuolar proton pump e subunit) (v-atpase 31 kda subunit) (p31). [source:swissprot;acc:p36543]	218.484	212.675	1.02731	
1139	ganglioside-induced differentiation-associated protein 1-like 1. [source:refseq;acc:nm_024034]	218.484	212.675	1.02731	
1140	dead (asp-glu-ala-asp) box polypeptide 39 isoform 1; nuclear rna helicase, decd variant of dead box family. [source:refseq;acc:nm_005804]	218.484	212.675	1.02731	
1141	ganglioside-induced differentiation-associated protein 1. [source:refseq;acc:nm_018972]	218.484	212.675	1.02731	
1142	vacuolar atp synthase subunit d (ec 3.6.3.14) (v-atpase d subunit) (vacuolar proton pump d subunit) (v-atpase 28 kda accessory protein). [source:swissprot;acc:q9y5k8]	218.484	212.675	1.02731	
1143	secretory pathway component sec31b-1. [source:refseq;acc:nm_015490]	218.484	212.675	1.02731	
1144	vacuolar atp synthase subunit h (ec 3.6.3.14) (v-atpase h subunit) (vacuolar proton pump h subunit) (v-atpase 50/57 kda subunits) (vacuolar proton pump subunit sfd) (cgi-11). [source:swissprot;acc:q9ui12]	218.484	212.675	1.02731	
1145	vacuolar atp synthase subunit f (ec 3.6.3.14) (v-atpase f subunit) (vacuolar proton pump f subunit) (v-atpase 14 kda subunit). [source:swissprot;acc:q16864]	218.481	212.675	1.0273	
1146	vacuolar atp synthase subunit b, kidney isoform (ec 3.6.3.14) (v- atpase b1 subunit) (vacuolar proton pump b isoform 1) (endomembrane proton pump 58 kda subunit). [source:swissprot;acc:p15313]	218.483	212.676	1.0273	
1147	peroxisomal membrane protein pex14 (peroxin-14) (peroxisomal membrane anchor protein pex14) (pts1 receptor docking protein). [source:swissprot;acc:o75381]	208.651	203.109	1.02729	
1148	ubiquitin. [source:swissprot;acc:p02248]	209.061	203.518	1.02724	
1149	bystin. [source:swissprot;acc:q13895]	239.505	233.185	1.0271	
1150	sorting nexin 1. [source:swissprot;acc:q13596]	209.868	215.522	1.02694	
1151	metaxin 1. [source:swissprot;acc:q13505]	199.552	204.925	1.02693	
1152	epidermal growth factor receptor pathway substrate 8-like protein 1 isoform c; epidermal growth factor receptor pathway substrate 8-related protein 1; eps8-related protein 1. [source:refseq;acc:nm_139204]	221.939	216.143	1.02682	
1153	epidermal growth factor receptor kinase substrate eps8. [source:swissprot;acc:q12929]	221.93	216.146	1.02676	
1154	inorganic pyrophosphatase (ec 3.6.1.1) (pyrophosphate phospho- hydrolase) (ppase). [source:swissprot;acc:q15181]	224.307	230.242	1.02646	
1155	inorganic pyrophosphatase 2 isoform 1. [source:refseq;acc:nm_176869]	224.307	230.242	1.02646	
1156	aryl-hydrocarbon interacting protein-like 1. [source:swissprot;acc:q9nzn9]	224.307	230.242	1.02646	
1157	ah receptor-interacting protein (aip) (immunophilin homolog ara9) (hbv-x associated protein 2). [source:swissprot;acc:o00170]	224.307	230.242	1.02646	
1158	epidermal growth factor receptor pathway substrate 8-like protein 2; eps8-related protein 2; epidermal growth factor receptor pathway substrate 8-related protein 2. [source:refseq;acc:nm_022772]	221.877	216.167	1.02641	
1159	proline synthetase co-transcribed bacterial homolog protein. [source:swissprot;acc:o94903]	170.28	165.898	1.02641	
1160	2-oxoglutarate dehydrogenase e1 component, mitochondrial precursor (ec 1.2.4.2) (alpha-ketoglutarate dehydrogenase). [source:swissprot;acc:q02218]	208.55	214.041	1.02633	
1161	kappa b-ras 1. [source:refseq;acc:nm_020345]	220.758	215.097	1.02632	
1162	i-kappa-b-interacting ras-like protein 2. [source:refseq;acc:nm_017595]	220.758	215.097	1.02632	
1163	snare associated protein snapin. [source:refseq;acc:nm_012437]	220.758	215.097	1.02632	
1164	transducin-like enhancer protein 4. [source:swissprot;acc:q04727]	219.438	213.818	1.02628	
1165	transducin-like enhancer protein 3 (esg3). [source:swissprot;acc:q04726]	219.401	213.785	1.02627	
1166	transducin-like enhancer protein 2 (esg2). [source:swissprot;acc:q04725]	219.374	213.759	1.02627	
1167	homeobox protein engrailed-2 (hu-en-2). [source:swissprot;acc:p19622]	219.399	213.784	1.02626	
1168	cpg binding protein (protein containing phd finger and cxxc domain 1). [source:swissprot;acc:q9p0u4]	219.399	213.784	1.02626	
1169	activator of basal transcription 1; tata-binding protein-binding protein; basal transcriptional activator. [source:refseq;acc:nm_013375]	219.399	213.784	1.02626	
1170	cytokine-like nuclear factor n-pac. [source:refseq;acc:nm_032569]	219.399	213.784	1.02626	
1171	hect type e3 ubiquitin ligase. [source:refseq;acc:nm_015052]	219.399	213.784	1.02626	
1172	transducin-like enhancer protein 1 (esg1). [source:swissprot;acc:q04724]	219.375	213.767	1.02623	
1173	candidate tumor suppressor in ovarian cancer 2. [source:refseq;acc:nm_080822]	229.243	235.246	1.02619	
1174	coatomer epsilon subunit (epsilon-coat protein) (epsilon-cop). [source:swissprot;acc:o14579]	187.964	192.849	1.02599	
1175	vacuolar atp synthase 16 kda proteolipid subunit (ec 3.6.3.14). [source:swissprot;acc:p27449]	218.186	212.672	1.02593	
1176	sarcoglycan zeta; zeta-sarcoglycan. [source:refseq;acc:nm_139167]	218.186	212.672	1.02593	
1177	golgi complex associated protein 1; golgi resident protein gcp60; peripherial benzodiazepine receptor associated protein; golgi phosphoprotein 1; pbr associated protein; pka (rialpha)-associated protein. [source:refseq;acc:nm_022735]	218.186	212.672	1.02593	
1178	delta-sarcoglycan (sg-delta) (35 kda dystrophin-associated glycoprotein) (35dag). [source:swissprot;acc:q92629]	218.186	212.672	1.02593	
1179	cellular modulator of immune recognition. [source:refseq;acc:nm_145021]	218.186	212.672	1.02593	
1180	vacuolar atp synthase 21 kda proteolipid subunit (ec 3.6.3.14) (hatpl). [source:swissprot;acc:q99437]	218.186	212.672	1.02593	
1181	gamma-sarcoglycan (gamma-sg) (35 kda dystrophin-associated glycoprotein) (35dag). [source:swissprot;acc:q13326]	218.186	212.672	1.02593	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/