Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1130 to 1179 of 3228 in total 
Value Type	Measured
Network Comparison Type	Divided
Interaction Map	High confidence
Filtered	1

Rank	description	red	green	network_comparison	
1130	similar to putative transmembrane protein; homolog of yeast golgi membrane protein yif1p (yip1p-interacting factor). [source:refseq;acc:nm_033557]	5790.65	6303.92	1.08864	
1131	aflatoxin b1 aldehyde reductase 2 (ec 1.-.-.-) (afb1-ar 2). [source:swissprot;acc:o95154]	5790.65	6303.92	1.08864	
1132	alpha/beta hydrolase domain containing protein 3; lung alpha/beta hydrolase 3. [source:refseq;acc:nm_138340]	5790.65	6303.92	1.08864	
1133	golgi membrane protein sb140; smooth muscle cell associated protein 5. [source:refseq;acc:nm_030799]	5790.65	6303.92	1.08864	
1134	alpha/beta hydrolase domain containing protein 1 isoform 2; lung alpha/beta hydrolase protein 1. [source:refseq;acc:nm_152870]	5790.65	6303.92	1.08864	
1135	methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial precursor (ec 1.2.1.27) (mmsdh). [source:swissprot;acc:q02252]	5790.67	6303.95	1.08864	
1136	10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [source:swissprot;acc:q04984]	5790.65	6303.92	1.08864	
1137	rab acceptor 1 (prenylated); prenylated rab acceptor 1. [source:refseq;acc:nm_006423]	5790.65	6303.92	1.08864	
1138	oligoribonuclease, mitochondrial precursor (ec 3.1.-.-) (small fragment nuclease) (cgi-114). [source:swissprot;acc:q9y3b8]	5790.65	6303.92	1.08864	
1139	choline o-acetyltransferase (ec 2.3.1.6) (choactase) (choline acetylase) (chat). [source:swissprot;acc:p28329]	5790.66	6303.95	1.08864	
1140	voltage-gated potassium channel beta-2 subunit (k+ channel beta-2 subunit) (kv-beta-2) (hkvbeta2). [source:swissprot;acc:q13303]	5790.65	6303.93	1.08864	
1141	aflatoxin b1 aldehyde reductase 1 (ec 1.-.-.-) (afb1-ar 1) (aldoketoreductase 7). [source:swissprot;acc:o43488]	5790.65	6303.93	1.08864	
1142	importin alpha-1 subunit (karyopherin alpha-1 subunit) (srp1-beta) (rag cohort protein 2) (nucleoprotein interactor 1) (npi-1). [source:swissprot;acc:p52294]	5789.07	6302.01	1.0886	
1143	homeobox protein engrailed-2 (hu-en-2). [source:swissprot;acc:p19622]	6281.21	6837.61	1.08858	
1144	cpg binding protein (protein containing phd finger and cxxc domain 1). [source:swissprot;acc:q9p0u4]	6281.21	6837.61	1.08858	
1145	40s ribosomal protein s30. [source:swissprot;acc:q05472]	5893.97	6416.07	1.08858	
1146	activator of basal transcription 1; tata-binding protein-binding protein; basal transcriptional activator. [source:refseq;acc:nm_013375]	6281.21	6837.61	1.08858	
1147	cytokine-like nuclear factor n-pac. [source:refseq;acc:nm_032569]	6281.21	6837.61	1.08858	
1148	hect type e3 ubiquitin ligase. [source:refseq;acc:nm_015052]	6281.21	6837.61	1.08858	
1149	transducin-like enhancer protein 3 (esg3). [source:swissprot;acc:q04726]	6280.74	6837.01	1.08857	
1150	mstp028 protein. [source:refseq;acc:nm_031954]	5838.87	6355.06	1.08841	
1151	alpha-centractin (centractin) (centrosome-associated actin homolog) (actin-rpv) (arp1). [source:swissprot;acc:p42024]	5322.74	5793.15	1.08838	
1152	beta-centractin (actin-related protein 1b) (arp1b). [source:swissprot;acc:p42025]	5322.74	5793.15	1.08838	
1153	swi/snf related, matrix associated, actin dependent regulator of chromatin subfamily b member 1 (integrase interactor 1 protein) (hsnf5) (baf47). [source:swissprot;acc:q12824]	5840.01	6355.56	1.08828	
1154	tumor necrosis factor, alpha-induced protein 1, endothelial (b12 protein). [source:swissprot;acc:q13829]	5840.65	6355.84	1.08821	
1155	transducin-like enhancer protein 4. [source:swissprot;acc:q04727]	6270.67	6823.73	1.0882	
1156	polymerase delta-interacting protein 1; tnfaip1-like. [source:refseq;acc:nm_178863]	5840.77	6355.89	1.08819	
1157	serine hydroxymethyltransferase, cytosolic (ec 2.1.2.1) (serine methylase) (glycine hydroxymethyltransferase) (shmt). [source:swissprot;acc:p34896]	5418.33	5895.2	1.08801	
1158	delta-aminolevulinic acid dehydratase (ec 4.2.1.24) (porphobilinogen synthase) (aladh). [source:swissprot;acc:p13716]	5489.18	5972.09	1.08797	
1159	kccr13l. [source:refseq;acc:nm_139179]	5538.8	6025.51	1.08787	
1160	dna repair protein rad51 homolog 1 (hrad51) (hsrad51). [source:swissprot;acc:q06609]	5538.8	6025.51	1.08787	
1161	n-acetyltransferase 5 (ec 2.3.1.-). [source:swissprot;acc:q9y6d2]	5315.76	5782.63	1.08783	
1162	nemo-like kinase; likely ortholog of mouse nemo like kinase. [source:refseq;acc:nm_016231]	5832.13	6343.59	1.0877	
1163	elks protein. [source:refseq;acc:nm_015064]	5832.13	6343.59	1.0877	
1164	sodium/iodide cotransporter (na(+)/i(-) cotransporter) (sodium-iodide symporter) (na+/i-symporter). [source:swissprot;acc:q92911]	6600.36	7178.84	1.08764	
1165	kidney and liver proline oxidase 1. [source:refseq;acc:nm_021232]	6604.44	7183.07	1.08761	
1166	solute carrier family 5 (iodide transporter), member 8; apical iodide transporter. [source:refseq;acc:nm_145913]	6606.3	7185.01	1.0876	
1167	sodium-dependent multivitamin transporter (na(+)-dependent multivitamin transporter). [source:swissprot;acc:q9y289]	6607.68	7186.45	1.08759	
1168	mitotic checkpoint protein bub3. [source:swissprot;acc:o43684]	5470.44	5949.49	1.08757	
1169	zinc finger protein 207. [source:swissprot;acc:o43670]	5470.44	5949.49	1.08757	
1170	ubiquitin-like protein smt3a. [source:swissprot;acc:p55854]	5826.34	6335.98	1.08747	
1171	ubiquitin-like protein smt3b (sentrin 2) (hsmt3). [source:swissprot;acc:p55855]	5826.29	6335.93	1.08747	
1172	acrc protein; putative nuclear protein. [source:refseq;acc:nm_052957]	5826.32	6335.95	1.08747	
1173	chaperone-activity of bc1 complex-like, mitochondrial precursor (chaperone-abc1-like). [source:swissprot;acc:q8ni60]	5799.35	6305.95	1.08735	
1174	cda11 protein. [source:refseq;acc:nm_032026]	5874.11	6387.23	1.08735	
1175	aarf domain containing kinase 2; putative ubiquinone biosynthesis protein aarf. [source:refseq;acc:nm_052853]	5799.35	6305.95	1.08735	
1176	aarf domain containing kinase 4. [source:refseq;acc:nm_024876]	5799.35	6305.95	1.08735	
1177	aarf domain containing kinase 1. [source:refseq;acc:nm_020421]	5799.35	6305.95	1.08735	
1178	pepsin a precursor (ec 3.4.23.1). [source:swissprot;acc:p00790]	4392.63	4776.19	1.08732	
1179	solute carrier family 20 (phosphate transporter), member 2; glvr-2; pit-2; gibbon ape leukemia virus receptor 2; murine leukemia virus, amphotropic; receptor. [source:refseq;acc:nm_006749]	4392.63	4776.19	1.08732	

Legend:
- Rank is the rank after comparing the two networks
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/