MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	description	Value Type	Rank	Network Comparison Type	red	Filtered	Interaction Map	network_comparison	green

Results: HTML CSV LaTeX

Showing element 501 to 550 of 14920 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence

description	Value Type	Rank	red	Filtered	network_comparison	green
6-phosphofructokinase, liver type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme b) (pfk-b). [swissprot;acc:p17858]	Measured	764	4250.18	1	1.11269	4729.12
	Ranked	1822	240.32		1.01151	243.085
	Squared	642	16123.9		1.17898	19009.7
	Rooted	1905	52.8713		1.02906	54.4076
6-phosphofructokinase, muscle type (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme a) (pfk-a) (phosphofructokinase-m). [swissprot;acc:p08237]	Measured	763	4250.54		1.11272	4729.67
	Ranked	1830	240.32		1.01144	243.069
	Squared	643	16126.5		1.17897	19012.6
	Rooted	1894	52.8726		1.02913	54.4127
6-phosphofructokinase, type c (ec 2.7.1.11) (phosphofructokinase 1) (phosphohexokinase) (phosphofructo-1-kinase isozyme c) (pfk-c) (6-phosphofructokinase, platelet type). [swissprot;acc:q01813]	Measured	759	4254.62		1.11315	4736.03
	Ranked	1883	240.317		1.01067	242.881
	Squared	644	16156.3		1.17886	19046
	Rooted	1846	52.887		1.02996	54.4715
6-phosphogluconate dehydrogenase, decarboxylating (ec 1.1.1.44). [swissprot;acc:p52209]	Measured	1339	5988.06		1.07964	6464.94
	Ranked	2274	213.642		1.00542	214.801
	Squared	922	27031.3		1.15634	31257.4
	Rooted	2041	63.5421		1.02698	65.2562
6-phosphogluconolactonase (ec 3.1.1.31) (6pgl). [swissprot;acc:o95336]	Measured	1627	6038.46		1.07046	6463.9
	Ranked	1584	216.891		1.01633	220.432
	Squared	899	29345.7		1.15875	34004.2
	Rooted	2366	62.9164		1.01725	64.002
6-pyruvoyl tetrahydrobiopterin synthase (ec 4.2.3.12) (ptps) (ptp synthase). [swissprot;acc:q03393]	Measured	2904	0.00001		1	0.00001
	Ranked
	Squared
	Rooted
60 kda heat shock protein, mitochondrial precursor (hsp60) (60 kda chaperonin) (cpn60) (heat shock protein 60) (hsp-60) (mitochondrial matrix protein p1) (p60 lymphocyte protein) (hucha60). [swissprot;acc:p10809]	Measured	1313	5457.14		1.08112	5899.85
	Ranked	2588	222.305		1.00151	222.64
	Squared	1238	23538.3		1.13485	26712.4
	Rooted	1830	60.2038		1.03036	62.0316
60 kda tat interactive protein (tip60) (hiv-1 tat interactive protein) (cpla(2) interacting protein). [swissprot;acc:q92993]	Measured	1751	6011.57		1.06711	6414.98
	Ranked	826	223.186		1.04335	213.912
	Squared	2621	31749.4		1.03095	30796.3
	Rooted	821	61.3164		1.06394	65.2371
60s acidic ribosomal protein p0 (l10e). [swissprot;acc:p05388]	Measured	2258	5150.31		1.04616	5388.05
	Ranked	1092	226.203		1.02941	232.855
	Squared	2254	22719.3		1.08197	24581.5
	Rooted	2720	58.3416		1.00112	58.4068
60s acidic ribosomal protein p1. [swissprot;acc:p05386]	Measured	313	6131.07	0	1.09921	6739.34
		2418	4857.03	1	1.03763	5039.78
	Ranked	233	9586.97	0	1.1015	10560
		898	229.171	1	1.03874	238.048
	Squared	381	49458.1	0	1.10427	54614.9
		2326	20706.1	1	1.07514	22261.9
	Rooted	377	45.8794	0	1.03908	47.6722
		2564	56.832	1	1.00907	56.3214
60s acidic ribosomal protein p2. [swissprot;acc:p05387]	Measured	2743	4824.49		1.0022	4813.92
	Ranked	720	231.92		1.05396	244.435
	Squared	2745	21770.6		1.00342	21696.3
	Rooted	1708	56.1247		1.03266	54.3497
60s ribosomal protein l10 (qm protein) (tumor suppressor qm) (laminin receptor homolog). [swissprot;acc:p27635]	Measured	269	1217.92	0	1.12309	1367.83
		2233	3614.08	1	1.04754	3450.07

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.