MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 11214 to 11263 of 12912 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1
red  : 0.00001
green  : 0.00001
network_comparison  : 1

Rank	description	Value Type
2804	barrier-to-autointegration factor (breakpoint cluster region protein 1). [swissprot;acc:o75531]	Ranked
		Squared
		Rooted
2805	phosphofurin acidic cluster sorting protein 1 isoform 1; cytosolic sorting protein pacs-1. [refseq;acc:nm_018026]	Measured
		Ranked
		Squared
		Rooted
2806	spry domain-containing socs box protein ssb-4. [refseq;acc:nm_080862]	Measured
		Ranked
		Squared
		Rooted
2807	ras-related protein rab-1b. [swissprot;acc:q9h0u4]	Measured
		Ranked
		Squared
		Rooted
2808	dna ligase iv (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p49917]	Measured
		Ranked
		Squared
		Rooted
2809	polyhomeotic like 3; early development regulator 3; polyhomeotic 3. [refseq;acc:nm_024947]	Measured
		Ranked
		Squared
		Rooted
2810	udp glycosyltransferase 2 family, polypeptide a1; udp glucuronosyltransferase 2 family, polypeptide a1. [refseq;acc:nm_006798]	Measured
		Ranked
		Squared
		Rooted
2811	vascular endothelial growth factor b precursor (vegf-b) (vegf related factor) (vrf). [swissprot;acc:p49765]	Measured
		Ranked
		Squared
		Rooted
2812	mob-lak. [refseq;acc:nm_130807]	Measured
		Ranked
		Squared
		Rooted
2813	histone deacetylase 3 (hd3) (rpd3-2). [swissprot;acc:o15379]	Measured
		Ranked
		Squared
		Rooted
2814	spry domain-containing socs box protein ssb-1. [refseq;acc:nm_025106]	Measured
		Ranked
		Squared
		Rooted
2815	g protein-coupled receptor 66. [refseq;acc:nm_006056]	Measured
		Ranked
		Squared
		Rooted
2816	tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702]	Measured
		Ranked
		Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.