Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank Filtered description Value Type Network Comparison Type green Interaction Map red network_comparison
Results: HTML CSV LaTeX Showing element 101 to 150 of 9634 in total
Value Type  : Measured
Network Comparison Type  : Divided
Rank
Filtered
description
green
Interaction Map
red
network_comparison
26 0 fatty acid desaturase 1; linoleoyl-coa desaturase (delta-6-desaturase)-like 1; delta-5 desaturase; delta-5 fatty acid desaturase. [refseq;acc:nm_013402] 662 High confidence 153 4.3268
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] 47 Low confidence 143 3.04255
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-12 subunit. [swissprot;acc:q9ubi6] 892.67 High confidence 1833.01 2.0534
sperm associated antigen 7. [refseq;acc:nm_004890] 19280.8 Low confidence 23318 1.20939
27 0 melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801] 35.5 105.5 2.97183
phenylethanolamine n-methyltransferase (ec 2.1.1.28) (pnmtase) (noradrenaline n-methyltransferase). [swissprot;acc:p11086] 139 High confidence 570 4.10072
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-4 subunit. [swissprot;acc:p50150] 895.134 1834.33 2.04922
protein kinase, interferon-inducible double stranded rna dependent activator; protein activator of the interferon-induced protein kinase. [refseq;acc:nm_003690] 4614.87 Low confidence 3840.85 1.20152
28 0 beta-carotene dioxygenase 2; putative b,b-carotene-9',10'-dioxygenase. [refseq;acc:nm_031938] 139 High confidence 570 4.10072
melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-3 subunit. [swissprot;acc:p29798] 895.194 High confidence 1834.36 2.04912
tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106] 3719.66 Low confidence 3098.94 1.2003
29 0 melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364] 35.5 105.5 2.97183
potassium voltage-gated channel, shal-related subfamily, member 2; voltage-sensitive potassium channel; voltage-gated potassium channel kv4.2. [refseq;acc:nm_012281] 434.911 High confidence 111.278 3.90833
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-8 subunit (gamma-9). [swissprot;acc:q9uk08] 895.507 1834.52 2.04858
tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616] 3739.84 Low confidence 3121.28 1.19818
30 0 dystrophin. [swissprot;acc:p11532] 111.739 High confidence 427.217 3.82335
melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356] 35.5 Low confidence 105.5 2.97183
1 bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090] 43509.4 36474.3 1.19288
guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 subunit. [swissprot;acc:p30670] 895.633 High confidence 1834.59 2.04837
31 0 dok-like protein. [refseq;acc:nm_024872] 0.00001 35 3500000
hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-10 subunit. [swissprot;acc:p50151] 895.697 High confidence 1834.63 2.04827
vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274] 43503.3 Low confidence 36469.3 1.19287
32 0 cell division protein kinase 8 (ec 2.7.1.-) (protein kinase k35). [swissprot;acc:p49336] 184 High confidence 598 3.25
melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-5 like subunit. [swissprot;acc:q9y3k8] 895.893 High confidence 1834.73 2.04793
nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333] 43368.8 Low confidence 36360.3 1.19275
33 0 lim domain binding 1; carboxy terminal lim domain protein 2; lim domain-binding factor-1. [refseq;acc:nm_003893] 39.8063 High confidence 12.6208 3.15402
melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(i)/g(s)/g(o) gamma-11 subunit. [swissprot;acc:p50152] 896.972 High confidence 1835.3 2.04611
vitelliform macular dystrophy 2-like protein 1. [refseq;acc:nm_017682] 43368.8 Low confidence 36360.3 1.19275
34 0 glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926] 47 High confidence 143 3.04255
melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(y), alpha subunit (alpha-11). [swissprot;acc:p29992] 907.546 High confidence 1836.71 2.02382
protein cgi-126 (protein hspc155). [swissprot;acc:q9y3c8] 6352.4 Low confidence 5339.5 1.1897
35 0 adp,atp carrier protein, liver isoform t2 (adp/atp translocase 3) (adenine nucleotide translocator 3) (ant 3). [swissprot;acc:p12236] 1377 High confidence 459.5 2.99674
melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358] 35.5 Low confidence 105.5 2.97183
1 deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233] 39358.1 33111.4 1.18866
guanine nucleotide-binding protein g(q), alpha subunit. [swissprot;acc:p50148] 907.564 High confidence 1836.71 2.02378
36 0 heparan sulfate 6-o-sulfotransferase 2. [refseq;acc:nm_147174] 56 157 2.80357
melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(z), alpha subunit (g(x) alpha chain) (gz-alpha). [swissprot;acc:p19086] 907.741 High confidence 1836.76 2.02344
proto-oncogene protein c-fos (cellular oncogene fos) (g0/g1 switch regulatory protein 7). [swissprot;acc:p01100] 7593.77 Low confidence 6462.09 1.17513
37 0 1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 934.348 High confidence 334.401 2.79409
melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361] 35.5 Low confidence 105.5 2.97183
1 guanine nucleotide-binding protein g(t), alpha-1 subunit (transducin alpha-1 chain). [swissprot;acc:p11488] 907.763 High confidence 1836.76 2.02339
jun dimerization protein. [refseq;acc:nm_130469] 7593.77 Low confidence 6462.09 1.17513
38 0 melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732] 35.5 105.5 2.97183
zinc finger protein slug (neural crest transcription factor slug) (snail homolog 2). [swissprot;acc:o43623] 120.429 High confidence 320.012 2.65727

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/