MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Rank	Gene	Hugo	description	Value Type	Interaction Map	Filtered	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1032 to 1081 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
network_comparison  : 0
green  : 0

Rank	Hugo	description	Value Type
3013	CENPB	major centromere autoantigen b (centromere protein b) (cenp-b). [swissprot;acc:p07199]	Rooted
3014	SLC25A19	mitochondrial deoxynucleotide carrier (mitochondrial uncoupling protein 1). [swissprot;acc:q9hc21]	Measured
			Ranked
			Squared
			Rooted
3015	NUP85	pericentrin 1; frount; nucleoporin nup75. [refseq;acc:nm_024844]	Measured
			Ranked
			Squared
			Rooted
3016	MRPS7	mitochondrial ribosomal protein s7; 30s ribosomal protein s7 homolog. [refseq;acc:nm_015971]	Measured
			Ranked
			Squared
			Rooted
3017	LRRFIP1	leucine rich repeat (in flii) interacting protein 1. [refseq;acc:nm_004735]	Measured
			Ranked
			Squared
			Rooted
3018	CRISP1	cysteine-rich secretory protein-1 precursor (crisp-1) (acidic epididymal glycoprotein homolog) (aeg-like protein) (arp). [swissprot;acc:p54107]	Measured
			Ranked
			Squared
			Rooted
3019	KLHDC3	testis intracellular mediator protein. [refseq;acc:nm_057161]	Measured
			Ranked
			Squared
			Rooted
3020	PACSIN1	protein kinase c and casein kinase substrate in neurons protein 1. [swissprot;acc:q9by11]	Measured
			Ranked
			Squared
			Rooted
3021	CRISP2	testis-specific protein tpx-1 precursor (cysteine-rich secretory protein-2) (crisp-2). [swissprot;acc:p16562]	Measured
			Ranked
			Squared
			Rooted
3022	NAGK	n-acetylglucosamine kinase (ec 2.7.1.59) (glcnac kinase). [swissprot;acc:q9uj70]	Measured
			Ranked
			Squared
			Rooted
3023	VAPB	vesicle-associated membrane protein-associated protein b/c (vamp- associated protein b/c) (vamp-b/vamp-c) (vap-b/vap-c). [swissprot;acc:o95292]	Measured
			Ranked
			Squared
			Rooted
3024	PIGT	phosphatidylinositol glycan class t precursor. [refseq;acc:nm_015937]	Measured
			Ranked
			Squared
			Rooted
3025	HMG1L1	dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4]	Measured
			Ranked
			Squared
			Rooted
3026	SLC36A1	solute carrier family 36 member 1; proton / amino acid symporter; lysosomal amino acid transporter 1. [refseq;acc:nm_078483]	Measured

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.