MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Network Comparison Type	Value Type	Interaction Map	Filtered	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 301 to 350 of 6456 in total

Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Network Comparison Type	green	red	network_comparison
151	myosin vc (myosin 5c). [swissprot;acc:q9nqx4]	Divided	46	55	1.19565
	protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22]	Subtracted	198.444	226.582	28.138
152	myosin va (myosin 5a) (dilute myosin heavy chain, non-muscle) (myosin heavy chain 12) (myoxin). [swissprot;acc:q9y4i1]	Divided	46	55	1.19565
	u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621]	Subtracted	198.444	226.582	28.138
153	chromosome 3p21.1 gene sequence. [refseq;acc:nm_013286]	Divided	298.263	249.663	1.19466
	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]	Subtracted	198.444	226.582	28.138
154	musashi 2 isoform a. [refseq;acc:nm_138962]		199.458	227.491	28.033
	regulator of g-protein signaling 19 (rgs19) (g-alpha interacting protein) (gaip protein). [swissprot;acc:p49795]	Divided	298.263	249.663	1.19466
155	musashi 1. [refseq;acc:nm_002442]	Subtracted	199.458	227.491	28.033
	putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37]	Divided	298.263	249.663	1.19466
156	nuclear protein ukp68. [refseq;acc:nm_024824]	Subtracted	199.458	227.491	28.033
	regulator of g-protein signaling 20 (rgs20) (regulator of gz- selective protein signaling 1) (gz-selective gtpase-activating protein) (g(z)gap). [swissprot;acc:o76081]	Divided	298.263	249.663	1.19466
157	neurogenic differentiation factor 2 (neurod2). [swissprot;acc:q15784]	Subtracted	284	312	28
	transcription factor lbx1. [swissprot;acc:p52954]	Divided	298.263	249.663	1.19466
158	chromodomain helicase-dna-binding protein 3 (chd-3) (mi-2 autoantigen 240 kda protein) (mi2-alpha). [swissprot;acc:q12873]	Subtracted	284	312	28
	mosaic protein lgn. [swissprot;acc:p81274]	Divided	298.263	249.663	1.19466
159	doc-1 related protein (doc-1r). [swissprot;acc:o75956]	Subtracted	284	312	28
	regulator of g-protein signaling 17 (rgs17). [swissprot;acc:q9ugc6]	Divided	298.263	249.663	1.19466
160	guanine nucleotide-binding protein g(o), alpha subunit 1. [swissprot;acc:p09471]
	neurogenic differentiation factor 6 (neurod6) (my051 protein). [swissprot;acc:q96nk8]	Subtracted	284	312	28
161	neurogenic differentiation factor 1 (neurod1) (neurod). [swissprot;acc:q13562]
	rap1 gtpase-activating protein 1 (rap1gap). [swissprot;acc:p47736]	Divided	298.263	249.663	1.19466
162	atlastin; guanylate-binding protein 3. [refseq;acc:nm_015915]	Subtracted	170	142	28
	nostrin. [refseq;acc:nm_052946]	Divided	249.187	209.299	1.19058
163	beta-arrestin 2 (arrestin, beta 2). [swissprot;acc:p32121]	Subtracted	105	133	28
	eap30 subunit of ell complex. [refseq;acc:nm_007241]	Divided	249.187	209.299	1.19058
164	beta-arrestin 1 (arrestin, beta 1). [swissprot;acc:p49407]	Subtracted	105	133	28
	liv-1 protein, estrogen regulated. [refseq;acc:nm_012319]	Divided	249.187	209.299	1.19058
165	glutamate decarboxylase, 65 kda isoform (ec 4.1.1.15) (gad-65) (65 kda glutamic acid decarboxylase). [swissprot;acc:q05329]
	spermatogenesis associated 6. [refseq;acc:nm_019073]	Subtracted	105	133	28
166	gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747]	Divided	249.187	209.299	1.19058
	neurogenic differentiation factor 4 (neurod4). [swissprot;acc:q9hd90]	Subtracted	284	312	28
167	amp deaminase 2 (ec 3.5.4.6) (amp deaminase isoform l). [swissprot;acc:q01433]		105	133
	glutamate decarboxylase, 67 kda isoform (ec 4.1.1.15) (gad-67) (67 kda glutamic acid decarboxylase). [swissprot;acc:q99259]	Divided	249.187	209.299	1.19058
168	chromodomain helicase dna binding protein 5. [refseq;acc:nm_015557]	Subtracted	284	312	28
	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	Divided	98.0548	82.5916	1.18722
169	apg3p; pc3-96 protein. [refseq;acc:nm_022488]
	cyclin-dependent kinase 2-associated protein 1 (cdk2-associated protein 1) (putative oral cancer suppressor) (deleted in oral cancer- 1) (doc-1). [swissprot;acc:o14519]	Subtracted	284	312	28
170	huntingtin interacting protein c. [refseq;acc:nm_012272]		200.417	227.971	27.554
	nucleolysin tia-1 (rna-binding protein tia-1) (p40-tia-1) [contains: p15-tia-1]. [swissprot;acc:p31483]	Divided	192.715	227.199	1.17894
171	nucleolysin tiar (tia-1 related protein). [swissprot;acc:q01085]		192.823	227.202	1.17829
	short transient receptor potential channel 4 (trpc4) (trp-related protein 4) (htrp-4) (htrp4). [swissprot;acc:q9ubn4]	Subtracted	228.784	201.478	27.306
172	cg9578-like; yeast ypr037w and worm c02c2.6 predicted proteins-like. [refseq;acc:nm_152902]	Divided	205.556	174.667	1.17685
	ebp50-pdz interactor of 64 kda (epi64 protein). [swissprot;acc:q9bxi6]	Subtracted	228.752	201.515	27.237
173	short transient receptor potential channel 5 (trpc5) (htrp-5) (htrp5). [swissprot;acc:q9ul62]
	small nuclear ribonucleoprotein sm d1 (snrnp core protein d1) (sm-d1) (sm-d autoantigen). [swissprot;acc:p13641]	Divided	193.056	227.032	1.17599
174	dgcr14 protein (digeorge syndrome critical region 14) (es2 protein). [swissprot;acc:q96df8]		286	335	1.17133
	luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	Subtracted	200.968	228.1	27.132
175	cop9 constitutive photomorphogenic homolog subunit 3; cop9 complex subunit 3; jab1-containing signalosome subunit 3. [refseq;acc:nm_003653]	Divided	234.187	199.949	1.17123
	luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	Subtracted	201.006	228.085	27.079

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.