MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	green	Gene	network_comparison	Value Type	red	Interaction Map	Network Comparison Type	Rank	description

Results: HTML CSV LaTeX

Showing element 1 to 32 of 32 in total

Rank  : 8

Filtered	green	network_comparison	Value Type	red	Interaction Map	Network Comparison Type	description
0	0.00001	159148	Squared	1.59148	High confidence	Divided	ero1-like. [refseq;acc:nm_014584]
		360555	Rooted	3.60555	Low confidence		homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]
		905539		9.05539	High confidence		ero1-like. [refseq;acc:nm_014584]
	43	4300000	Measured	0.00001			synbindin (trs23 homolog) (hematopoietic stem/progenitor cell protein 172) (hspc172) (ptd009) (cgi-104). [swissprot;acc:q9y296]
	56.7758	15.3379	Rooted	72.1137		Subtracted	nif3-like protein 1 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 1) (my018 protein) (mds015). [swissprot;acc:q9gzt8]
	111.067	15.292		126.359	Low confidence		nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]
	6410	75.4118	Measured	85		Divided	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
	7500.75	2393.82		5106.93	High confidence	Subtracted	nucleoporin nup43 (p42). [swissprot;acc:q8nfh3]
	8770.72	1232.83		7537.89	Low confidence		zinc finger protein 277. [swissprot;acc:q9nrm2]
	13216	1.68629	Ranked	22286		Divided	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]
		9070			High confidence	Subtracted	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]
	19295.9	11098	Squared	1.73869	Low confidence	Divided	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]
	19873	8983.6	Ranked	10889.4		Subtracted	ubiquitously transcribed y chromosome tetratricopeptide repeat protein (ubiquitously transcribed tpr protein on the y chromosome). [swissprot;acc:o14607]
	21888	1.89918		11525	High confidence	Divided	nuclear receptor co-repressor/hdac3 complex subunit tblr1 (tbl1- related protein 1). [swissprot;acc:q9bzk7]
	61843.5	16419.5	Squared	45424	Low confidence	Subtracted	similar to zinc finger protein 277. [sptrembl;acc:q8wwa6]
	386144	28560		414704	High confidence		transcription initiation factor tfiid 135 kda subunit (tafii-135) (tafii135) (tafii-130) (tafii130). [swissprot;acc:o00268]
1	18.4255	1.84327	Rooted	33.9632		Divided	db83 protein. [swissprot;acc:p57088]
	27.2805	11.544	Squared	314.926
	45.9728	18.8343	Rooted	27.1385	Low confidence	Subtracted	oxysterol binding protein-related protein 6 (osbp-related protein 6) (orp-6). [swissprot;acc:q9bzf3]
	47.6922	1.49674		31.8641		Divided	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
	168.796	23.245		145.551	High confidence	Subtracted	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [swissprot;acc:q9h999]
	240	1.325	Ranked	318	Low confidence	Divided	oxysterol binding protein-related protein 7 (osbp-related protein 7) (orp-7). [swissprot;acc:q9bzf2]
	247.246	58.226		305.472		Subtracted	thyroid receptor interacting protein 8 (trip-8) (fragment). [swissprot;acc:q15652]
	322	1.49767		215	High confidence	Divided	hbs1-like. [refseq;acc:nm_006620]
	339.5	3.39764	Measured	1153.5			db83 protein. [swissprot;acc:p57088]
	362	74	Ranked	288		Subtracted	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]
	5058.5	1.54317	Measured	3278	Low confidence	Divided	phosphatidylinositol-glycan biosynthesis, class f protein (pig-f). [swissprot;acc:q07326]
	6056.43	2.38136	Squared	2543.26
	28492	7307	Measured	21185	High confidence	Subtracted	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]
	39358.1	6246.7		33111.4	Low confidence		deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]
	192141	85915	Squared	106226			mitochondrial solute carrier protein. [refseq;acc:nm_145305]
	354894	104591		250303	High confidence		deoxyribonuclease ii beta isoform 1 precursor; deoxyribonuclease ii beta; endonuclease dlad. [refseq;acc:nm_021233]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.