Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Rank Gene description Value Type Network Comparison Type Interaction Map Filtered green red network_comparison
Results: HTML CSV LaTeX Showing element 551 to 600 of 7460 in total
Value Type  : Measured
Interaction Map  : High confidence
Rank
description
Network Comparison Type
Filtered
green
red
network_comparison
138 tumor suppressor p53-binding protein 2 (p53-binding protein 2) (53bp2) (bcl2-binding protein) (bbp). [swissprot;acc:q13625] Subtracted 1 13277.9 15182.5 1904.6
ubiquitin-conjugating enzyme e2-17 kda 3 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2(17)kb 3). [swissprot;acc:p47986] Divided 0 154.804 204.382 1.32026
139 associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799] 561.038 736.737 1.31317
cell division control protein 2 homolog (ec 2.7.1.-) (p34 protein kinase) (cyclin-dependent kinase 1) (cdk1). [swissprot;acc:p06493] Subtracted 1 10876.4 12780.7 1904.3
peroxisomal 3,2-trans-enoyl-coa isomerase (ec 5.3.3.8) (dodecenoyl-coa delta-isomerase) (d3,d2-enoyl-coa isomerase) (dbi-related protein 1) (drs-1) (hepatocellular carcinoma-associated antigen 88). [swissprot;acc:o75521] 0 2924.8 3161.12 236.32
potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183] Divided 1 2099.49 2759.61 1.31442
140 homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774] Subtracted 698.5 2597.5 1899
kv channel interacting protein 2 isoform 4; a-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit. [refseq;acc:nm_173193] Divided 2100.27 2760.28 1.31425
tigger transposable element derived 6. [refseq;acc:nm_030953] Subtracted 0 438.605 202.374 236.231
vacuolar atp synthase subunit g 2 (ec 3.6.3.14) (v-atpase g subunit 2) (vacuolar proton pump g subunit 2) (v-atpase 13 kda subunit 2). [swissprot;acc:o95670] Divided 1222.89 934.726 1.30829
141 ccr4-not transcription complex, subunit 7 (ccr4-associated factor 1) (caf1) (btg1 binding factor 1). [swissprot;acc:q9uiv1] 891.114 1161.88 1.30385
hbs1-like. [refseq;acc:nm_006620] Subtracted 1 698.5 2597.5 1899
small nuclear ribonucleoprotein sm d2 (snrnp core protein d2) (sm-d2). [swissprot;acc:p43330] Divided 5782.08 4405.4 1.3125
tigger transposable element derived 7; jerky (mouse) homolog-like. [refseq;acc:nm_033208] Subtracted 0 438.035 202.163 235.872
142 metalloprotease 1; metalloprotease 1 (pitrilysin family). [refseq;acc:nm_014889] Divided 1 7090.37 9276.47 1.30832
presenilin-like protein 1 (ec 3.4.99.-) (sppl2b protein). [swissprot;acc:q8tct7] 0 1139 874 1.3032
tigger transposable element derived 1; jerky (mouse) homolog-like. [refseq;acc:nm_145702] Subtracted 438.016 202.156 235.86
transcription factor jun-d. [swissprot;acc:p17535] 1 7523.39 5638.2 1885.19
143 40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880] 0 1735.23 1499.4 235.83
beta-1,4 mannosyltransferase. [refseq;acc:nm_019109] Divided 1 7089.65 9275.1 1.30826
cleavage stimulation factor, 64 kda subunit (cstf 64 kda subunit) (cf-1 64 kda subunit). [swissprot;acc:p33240] Subtracted 13572.8 15427.2 1854.4
putative rna-binding protein 15 (rna binding motif protein 15) (one-twenty two protein). [swissprot;acc:q96t37] Divided 0 144 187 1.29861
144 integrin beta-3 precursor (platelet membrane glycoprotein iiia) (gpiiia) (cd61 antigen). [swissprot;acc:p05106] Subtracted 1843.92 1612.86 231.06
nucleolysin tia-1 (rna-binding protein tia-1) (p40-tia-1) [contains: p15-tia-1]. [swissprot;acc:p31483] 1 5945.32 4133.47 1811.85
sad1/unc-84 protein-like 1. [swissprot;acc:o94901] Divided 4362.61 3349.9 1.30231
uridine kinase-like 1. [swissprot;acc:q9nwz5] 0 821.711 633.433 1.29723
145 likely ortholog of rat cytochrome p450 4x1. [refseq;acc:nm_178033] 372.961 287.903 1.29544
nucleolysin tiar (tia-1 related protein). [swissprot;acc:q01085] Subtracted 1 5943.56 4136.36 1807.2
rna-binding protein nova-1 (neuro-oncological ventral antigen 1) (onconeural ventral antigen-1) (paraneoplastic ri antigen) (ventral neuron-specific protein 1). [swissprot;acc:p51513] 0 1932 2162.33 230.33
ubiquitin activating enzyme e1-like protein. [refseq;acc:nm_006395] Divided 1 12889.1 16771.5 1.30122
146 associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799] 8508.5 11068 1.30082
cop9 signalosome complex subunit 1 (g protein pathway suppressor 1) (gps1 protein) (mfh protein). [swissprot;acc:q13098] Subtracted 0 17126 17356 230
cytochrome p450 4f12 (ec 1.14.14.1) (cypivf12). [swissprot;acc:q9hcs2] Divided 377.574 291.639 1.29466
xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266] Subtracted 1 871 2671 1800
147 cytochrome p450 4f11 (ec 1.14.14.1) (cypivf11). [swissprot;acc:q9hbi6] Divided 0 378.206 292.152 1.29455
nanos (fragment). [sptrembl;acc:q8wy41] Subtracted 151 377 226
protein x 0004. [refseq;acc:nm_016301] 1 871 2671 1800
putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453] Divided 8508.5 11068 1.30082
148 associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]
cytochrome p450 4f8 (ec 1.14.14.1) (cypivf8). [swissprot;acc:p98187] 0 379.474 293.178 1.29435
pyrroline-5-carboxylate reductase (ec 1.5.1.2) (p5cr) (p5c reductase). [swissprot;acc:p32322] Subtracted 1023.76 1249.24 225.48
symplekin. [swissprot;acc:q92797] 1 13418.1 15213.4 1795.3
149 cytochrome p450 4f2 (ec 1.14.13.30) (cypivf2) (leukotriene-b4 omega- hydroxylase) (leukotriene-b4 20-monooxygenase) (cytochrome p450- ltb-omega). [swissprot;acc:p78329] Divided 0 379.474 293.178 1.29435
neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079] 1 8508.5 11068 1.30082
polyposis locus protein 1-like 1; likely ortholog of mouse polyposis locus protein 1-like 1. [refseq;acc:nm_138393] Subtracted 0 544.991 323.79 221.201
trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase (ec 2.1.1.61). [swissprot;acc:o75648] 1 13531.9 11736.6 1795.3
150 metaxin 1. [swissprot;acc:q13505] Divided 0 723.368 933.395 1.29035
pnas-18. [sptrembl;acc:q9bzu3] Subtracted 2035.28 2256.05 220.77
protein hspc134 (protein cda04). [swissprot;acc:q9by43] Divided 1 8508.5 11068 1.30082
small nuclear ribonucleoprotein sm d1 (snrnp core protein d1) (sm-d1) (sm-d autoantigen). [swissprot;acc:p13641] Subtracted 5954.48 4172.91 1781.57

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/