MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	Interaction Map	Filtered	green	red	network_comparison

Results: HTML CSV LaTeX

Showing element 1051 to 1100 of 3228 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	green	red	network_comparison
1051	17 beta-hydroxysteroid dehydrogenase. [sptrembl;acc:q13034]	217.998	211.449	1.03097
1052	retinol dehydrogenase 8 (all-trans); photoreceptor outer segment all-trans retinol dehydrogenase. [refseq;acc:nm_015725]
1053	proteasome subunit alpha type 5 (ec 3.4.25.1) (proteasome zeta chain) (macropain zeta chain) (multicatalytic endopeptidase complex zeta chain). [swissprot;acc:p28066]	200.84	207.04	1.03087
1054	60s ribosomal protein l21. [swissprot;acc:p46778]	217.263	223.958	1.03082
1055	hcv ns3-transactivated protein 1. [refseq;acc:nm_019048]	212.468	219.01	1.03079
1056	vacuolar atp synthase catalytic subunit a, ubiquitous isoform (ec 3.6.3.14) (v-atpase a subunit 1) (vacuolar proton pump alpha subunit 1) (v-atpase 69 kda subunit 1) (isoform va68). [swissprot;acc:p38606]
1057	asparagine synthetase [glutamine-hydrolyzing] (ec 6.3.5.4) (glutamine- dependent asparagine synthetase) (ts11 cell cycle control protein). [swissprot;acc:p08243]
1058	ataxin 2 related protein isoform a; ataxin-2 domain protein. [refseq;acc:nm_007245]	221.293	228.105	1.03078
1059	ataxin 2; olivopontocerebellar ataxia 2, autosomal dominant. [refseq;acc:nm_002973]
1060	nemo-like kinase; likely ortholog of mouse nemo like kinase. [refseq;acc:nm_016231]	211.648	218.162
1061	elks protein. [refseq;acc:nm_015064]
1062	zinc finger protein 174 (aw-1). [swissprot;acc:q15697]	278.239	269.963	1.03066
1063	zinc finger imprinted 2. [swissprot;acc:q9nzv7]	278.232	269.96	1.03064
1064	zinc finger protein 24 (zinc finger protein 191) (zinc finger protein kox17) (retinoic acid suppression protein a) (rsg-a). [swissprot;acc:p17028]	278.221	269.955	1.03062
1065	zinc finger protein 305. [swissprot;acc:o43309]	278.219	269.954
1066	zinc finger protein 18 (zinc finger protein kox11) (fragment). [swissprot;acc:p17022]	278.223	269.956
1067	zinc finger protein 215 (bwscr2 associated zinc-finger protein 2) (baz 2). [swissprot;acc:q9ul58]
1068	zinc finger protein 274 (zinc finger protein sp2114) (zinc finger protein hfb101) (zinc finger protein zfp2) (zf2). [swissprot;acc:q96gc6]	278.215	269.953	1.03061
1069	zinc finger protein 232. [swissprot;acc:q9uny5]	278.218	269.954
1070	zinc finger protein 99. [refseq;acc:nm_032164]
1071	dna-directed rna polymerase i 16 kda polypeptide (ec 2.7.7.6) (rpa16). [swissprot;acc:q9y2s0]	238.356	231.277
1072	zinc finger protein 213 (putative transcription factor cr53). [swissprot;acc:o14771]	278.217	269.954
1073	ww domain binding protein 2 (wbp-2). [swissprot;acc:q969t9]	210.485	216.901	1.03048
1074	coatomer beta' subunit (beta'-coat protein) (beta'-cop) (p102). [swissprot;acc:p35606]	179.697	174.387	1.03045
1075	coatomer gamma subunit (gamma-coat protein) (gamma-cop). [swissprot;acc:q9y678]
1076	coatomer zeta-1 subunit (zeta-1 coat protein) (zeta-1 cop) (cgi-120) (hspc181). [swissprot;acc:q9y3c3]
1077	coatomer delta subunit (delta-coat protein) (delta-cop) (archain). [swissprot;acc:p48444]
1078	peptidyl-prolyl cis-trans isomerase e (ec 5.2.1.8) (ppiase e) (rotamase e) (cyclophilin e) (cyclophilin 33). [swissprot;acc:q9unp9]
1079	coatomer zeta-2 subunit (zeta-2 coat protein) (zeta-2 cop). [swissprot;acc:q9p299]
1080	zinc finger protein 444; endothelial zinc finger protein 2. [refseq;acc:nm_018337]	278.093	269.896	1.03037
1081	40s ribosomal protein s30. [swissprot;acc:q05472]	216.875	223.44	1.03027
1082	phafin 2; ph and fyve domain-containing protein 2. [refseq;acc:nm_024613]	213.685	220.118	1.03011
1083	3-oxo-5-alpha-steroid 4-dehydrogenase 1 (ec 1.3.99.5) (steroid 5-alpha-reductase 1) (sr type 1) (s5ar). [swissprot;acc:p18405]
1084	3-oxo-5-alpha-steroid 4-dehydrogenase 2 (ec 1.3.99.5) (steroid 5-alpha-reductase 2) (sr type 2) (5 alpha-sr2). [swissprot;acc:p31213]
1085	dyskerin (nucleolar protein nap57) (cbf5 homolog). [swissprot;acc:o60832]	237.864	231.007	1.02968
1086	similar to zinc finger protein 277. [sptrembl;acc:q8wwa6]	243.679	236.679	1.02958
1087	zinc finger protein 277. [swissprot;acc:q9nrm2]
1088	annexin a11 (annexin xi) (calcyclin-associated annexin 50) (cap-50) (56 kda autoantigen). [swissprot;acc:p50995]	213.378	219.673	1.0295
1089	cleavage stimulation factor subunit 3; cleavage stimulation factor, 3' pre-rna, subunit 3, 77kd. [refseq;acc:nm_001326]	125.004	121.428	1.02945
1090	similar to ribosomal protein, large, p0. [sptrembl;acc:q96fq9]	232.88	226.218
1091	block 23. [sptrembl;acc:q8nhw5]	232.858	226.205	1.02941
1092	60s acidic ribosomal protein p0 (l10e). [swissprot;acc:p05388]	232.855	226.203
1093	coatomer alpha subunit (alpha-coat protein) (alpha-cop) (hepcop) (hep-cop) [contains: xenin (xenopsin-related peptide); proxenin]. [swissprot;acc:p53621]	182.647	177.432	1.02939
1094	annexin a7 (annexin vii) (synexin). [swissprot;acc:p20073]	213.385	219.655	1.02938
1095	mitochondrial gtp binding protein isoform v. [refseq;acc:nm_032620]	207.463	213.552	1.02935
1096	nadh-ubiquinone oxidoreductase b22 subunit (ec 1.6.5.3) (ec 1.6.99.3) (complex i-b22) (ci-b22). [swissprot;acc:q9y6m9]	206.339	212.345	1.02911
1097	probable calcium-transporting atpase kiaa0703 (ec 3.6.3.8). [swissprot;acc:o75185]	203.208	209.123
1098	adapter-related protein complex 3 mu 1 subunit (mu-adaptin 3a) (ap-3 adapter complex mu3a subunit). [swissprot;acc:q9y2t2]	211.185	217.323	1.02906
1099	adapter-related protein complex 3 mu 2 subunit (clathrin coat assembly protein ap47 homolog 2) (clathrin coat associated protein ap47 homolog 2) (golgi adaptor ap-1 47 kda protein homolog 2) (ha1 47 kda subunit homolog 2) (clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (p47b). [swissprot;acc:p53677]	211.183	217.315	1.02904
1100	calcium-transporting atpase type 2c, member 1 (ec 3.6.3.8) (atpase 2c1) (atp-dependent ca(2+) pump pmr1) (hussy-28). [swissprot;acc:p98194]	203.183	209.052	1.02889

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.