MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	description	Network Comparison Type	red	network_comparison	Value Type	Interaction Map	Filtered	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 25824 in total

Interaction Map  : High confidence
Filtered  : 1

Rank	description	Network Comparison Type	red	network_comparison	Value Type	green
1	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Subtracted	215	107	Ranked	322
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]		41482.5	8126	Measured	33356.5
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Divided	10	2.4	Ranked	24
		Subtracted	468498	145743	Squared	322755
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Divided	21.225	2.30547	Rooted	48.9336
			48.0356	28.2513	Squared	1357.07
			450.5	5.31521	Measured	2394.5
		Subtracted	21.225	27.7086	Rooted	48.9336
2	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]		41482.5	8126	Measured	33356.5
	hbs1-like. [refseq;acc:nm_006620]		215	107	Ranked	322
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Divided	15	1.86667		28
		Subtracted	407289	143938	Squared	263351
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Divided	21.225	2.30547	Rooted	48.9336
			48.0356	28.2513	Squared	1357.07
			450.5	5.31521	Measured	2394.5
		Subtracted	21.225	27.7086	Rooted	48.9336
3	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Divided	15	1.86667	Ranked	28
		Subtracted	407289	143938	Squared	263351
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]		41482.5	8126	Measured	33356.5
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Divided	50.9657	1.92839	Rooted	26.4292
			1596.92	13.8285	Squared	115.48
			2597.5	3.71868	Measured	698.5
		Subtracted	50.9657	24.5365	Rooted	26.4292
	rad50-interacting protein 1. [refseq;acc:nm_021930]		337	105	Ranked	232
4	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Divided	15	1.86667		28
		Subtracted	407289	143938	Squared	263351
	cytohesin 4. [swissprot;acc:q9uia0]		41482.5	8126	Measured	33356.5
	hbs1-like. [refseq;acc:nm_006620]	Divided	50.9657	1.92839	Rooted	26.4292
			1596.92	13.8285	Squared	115.48
			2597.5	3.71868	Measured	698.5
		Subtracted	50.9657	24.5365	Rooted	26.4292
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]		337	105	Ranked	232
5	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]		145.551	23.245	Rooted	168.796
	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]		41482.5	8126	Measured	33356.5
	cytohesin 4. [swissprot;acc:q9uia0]	Divided	15	1.86667	Ranked	28
		Subtracted	407289	143938	Squared	263351
	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Divided	33.9632	1.84327	Rooted	18.4255
			314.926	11.544	Squared	27.2805
			1153.5	3.39764	Measured	339.5
	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Subtracted	212	97	Ranked	309
6	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Divided	15	1.86667		28
		Subtracted	407289	143938	Squared	263351
	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Divided	33.9632	1.84327	Rooted	18.4255
			314.926	11.544	Squared	27.2805
			1153.5	3.39764	Measured	339.5
	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]	Subtracted	145.551	23.245	Rooted	168.796
	protein x 0004. [refseq;acc:nm_016301]		212	97	Ranked	309
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]		44490.5	7563	Measured	36927.5
7	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]		21185	7307		28492
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Divided	215	1.49767	Ranked	322

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.