MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	green	Rank	Gene	Value Type	Interaction Map	Network Comparison Type	Filtered	red	network_comparison

Results: HTML CSV LaTeX

Showing element 501 to 550 of 12912 in total

Interaction Map  : High confidence
Network Comparison Type  : Divided
Filtered  : 1

description	green	Rank	Value Type	red	network_comparison
60s ribosomal protein l14 (cag-isl 7). [swissprot;acc:p50914]	45.6718	387	Rooted	50.3345	1.10209
	266.673	306	Ranked	242.153	1.10126
	3423.89	2074	Measured	3614.91	1.05579
	13562.6	2003	Squared	12429.9	1.09113
60s ribosomal protein l15. [swissprot;acc:p39030]	57.9477	2238	Rooted	59.1718	1.02112
	230.978	604	Ranked	217.862	1.0602
	5006.1	2532	Measured	4888.72	1.02401
	20351.7	1089	Squared	17766.4	1.14552
60s ribosomal protein l17 (l23). [swissprot;acc:p18621]	45.4333	343	Rooted	50.3169	1.10749
	267.335	281	Ranked	241.808	1.10557
	3384.59	1894	Measured	3598.08	1.06308
	13390.2	2212	Squared	12360.4	1.08331
60s ribosomal protein l18. [swissprot;acc:q07020]	50.0947	969	Rooted	52.9804	1.0576
	254.667	485	Ranked	237.109	1.07405
	4095.53	2694	Measured	4113.79	1.00446
	17067.9	1618	Squared	15399.5	1.10834
60s ribosomal protein l18a. [swissprot;acc:q02543]	59.3786	770	Rooted	55.6817	1.06639
	224.958	860	Ranked	234.025	1.04031
	5226.71	806	Measured	4708.61	1.11003
	21540.4	1128	Squared	18854.4	1.14246
60s ribosomal protein l19. [swissprot;acc:p14118]	46.3081	435	Rooted	50.832	1.09769
	264.729	319	Ranked	240.73	1.09969
	3499.2	2136	Measured	3687.49	1.05381
	13918.3	2054	Squared	12769	1.09001
60s ribosomal protein l21. [swissprot;acc:p46778]	63.2237	1051	Rooted	60.1366	1.05133
	217.263	1054	Ranked	223.958	1.03082
	5957.99	1510	Measured	5546.11	1.07426
	26738.9	2453	Squared	25226.2	1.05997
60s ribosomal protein l22 (epstein-barr virus small rna associated protein) (eber associated protein) (eap) (heparin binding protein hbp15). [swissprot;acc:p35268]	72.5201	2667	Rooted	72.1844	1.00465
	200.413	2205	Ranked	199.129	1.00645
	7741.14	2673	Measured	7780.98	1.00515
	36568.4	2530	Squared	38544.3	1.05403
60s ribosomal protein l23 (l17). [swissprot;acc:p23131]	46.0607	384	Rooted	50.7723	1.10229
	265.717	293	Ranked	240.782	1.10356
	3482.34	2115	Measured	3672.49	1.0546
	13887.8	1838	Squared	12666.8	1.09639
60s ribosomal protein l23a. [swissprot;acc:p29316]	45.9373	424	Rooted	50.4703	1.09868
	265.945	323	Ranked	241.884	1.09947
	3463.88	2175	Measured	3642.13	1.05146
	13806.3	1950	Squared	12632.4	1.09293
60s ribosomal protein l24 (l30). [swissprot;acc:p38663]	73.3177	1128	Rooted	69.8977	1.04893
	198.86	1767	Ranked	201.288	1.01221
	7911.25	727	Measured	7087.23	1.11627
	37652.3	420	Squared	30924.3	1.21756
60s ribosomal protein l26. [swissprot;acc:q02877]	45.5599	374	Rooted	50.2549	1.10305
	267.008	302	Ranked	242.326	1.10185
	3409.48	2051	Measured	3601.97	1.05646
	13513	1997	Squared	12380.1	1.09151
60s ribosomal protein l28. [swissprot;acc:p46779]	65.4287	1506	Rooted	63.0816	1.03721
	213.61	1882	Ranked	215.896	1.0107

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.