MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	green	red	description	Rank	Interaction Map	Gene	Value Type	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0
green  : 0
red  : 0
network_comparison  : 0
Network Comparison Type  : Subtracted

description	Rank	Interaction Map	Value Type
brca1 associated protein. [refseq;acc:nm_006768]	502	High confidence	Measured
			Ranked
			Squared
			Rooted
cobw-like protein. [refseq;acc:nm_018491]	839	Low confidence	Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	838		Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltransferase. [sptrembl;acc:q14390]	841		Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	842		Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]	837		Measured
			Ranked
			Squared
			Rooted
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	843		Measured
			Ranked
			Squared
			Rooted
h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	501	High confidence	Measured
			Squared
			Rooted
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	495		Measured
			Squared
			Rooted
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	494		Measured
			Squared
			Rooted
histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	497		Measured
			Squared
			Rooted
homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	499		Measured
			Squared
			Rooted
	501		Ranked
mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	496		Measured
			Squared
			Rooted
rwd domain containing 1; ptd013 protein; cgi-24 protein. [refseq;acc:nm_015952]	500		Measured
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.